Clinical trials: Development Disorders
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Genetic Diseases
Decoding Developmental Disorders in Humams
The DEVO-DECODE project aims to align our currently limited knowledge currently limited knowledge of the genetic architecture of developmental with our more advanced knowledge of their "phenome".
- Trial name
- devodecode (NCT06260319)
- Testing
- Whole genome sequencing and Genome-Epigenome-Phenome Associations
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Leukemia
Combination Chemotherapy, Interleukin-2, and Peripheral Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia
RATIONALE: Giving combination chemotherapy before a peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them.
- Trial name
- NCT00004128
- Testing
- aldesleukin, filgrastim, busulfan
- Volunteers
- 2,000 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pulp Necrosis, Regeneration
Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
This multi-center exploratory clinical trial is a randomized trial designed to test whether a regenerative endodontic procedure using tissue engineering principles (REGENDO), or a revascularization (REVASC) endodontic procedure…
- Trial name
- NCT01976065
- Testing
- Triple Antibiotic Paste, Standard Treatment
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Kenneth Hargreaves
Autism Spectrum Disorder
Cognoa Autism Spectrum Disorder (ASD) Digital Therapeutic Engagement and Usability Study
Cognoa will measure usability, engagement with the device, and changes in parent-reported socialization during a 4-week period of intervention at home with the Cognoa ASD therapeutic device.
- Trial name
- NCT04326231
- Testing
- Usability assessment of Cognoa ASD Therapeutic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognoa, Inc.
Malnutrition
The Impact on School Feeding on Children's Growth and Development
In order to improve child nutrition, the Poverty Reduction Strategy adopted by the Government of Bangladesh (GoB) has called for the initiation of a school feeding programme for primary school children living in poor and…
- Trial name
- schoolfeed (NCT03263377)
- Testing
- The school feeding intervention
- Volunteers
- 3,006 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hydrocephalus
Improving Infant Hydrocephalus Outcomes in Uganda
Neonatal postinfectious hydrocephalus (PIH) is a major public health problem in East Africa.The standard treatment has long been placement of a ventriculoperitoneal shunt (VPS) but these devices require life-long maintenance and…
- Trial name
- NCT03650101
- Testing
- ETV/CPC
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
PEACE for ImPACT Study
Investigators will test the impact of the PEACE implementation toolkit and determine the level of implementation support needed to improve early intervention providers use of caregiver coaching with families of young children…
- Trial name
- NCT06374381
- Testing
- PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Prematurity, Neurodevelopmental Disorder
Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Preterm infants are vulnerable to brain injury, nutritional deficiencies and poor early growth which places them at increased risk for developmental problems later in life.
- Conditions
- Prematurity, Neurodevelopmental Disorder, Carnitine Deficiency
- Trial name
- NCT01783041
- Testing
- L-carnitine, 5% Dextrose
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- Montefiore Medical Center
Growth Hormone Deficiency
A Long-Term Safety Study of Somavaratan in Japanese Children With Growth Hormone Deficiency
This study is a multi-center, open-label safety study assessing long-term somavaratan administration.
- Trial name
- NCT03145831
- Testing
- Somavaratan
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Versartis Inc.
Autism, Emotion Regulation Difficulties
Enhancing Emotion Regulation in Children With Autism Through Extended Reality
Pilot study on the development of an Extended Reality (XR) application to support emotion regulation in children with Autism Spectrum Disorder (ASD) (random assignment to an experimental group, N = 10, and a control group, N =…
- Trial name
- ERAC-XR (NCT07838272)
- Testing
- Extended Reality, Emotion regulation coaching
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Johannes Kepler University of Linz
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Autism Spectrum Disorder
Care Pathway for Children With Autism Spectrum Disorder Included in the ELENA Cohort
Autism Spectrum Disorder (ASD) is lifelong neurodevelopmental disorder that affect social communication and interaction and includes limited and repetitive patterns of behavior (DSM 5).
- Trial name
- ELENA-SNDS (NCT04292522)
- Where
- France
- Volunteers
- 903 people
- Sponsor
- University Hospital, Montpellier
Attention Deficit Hyperactivity Disorder Symptoms
Development of a Mobile App for an Executive Functioning Intervention for Adolescents
This study develops an initial prototype of a mobile tool that will support clinician-directed behavioral/organizational skills treatment for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) with input guided from…
- Trial name
- NCT04018794
- Testing
- Behavioral/organizational skills intervention augmented with digital health application
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Asthma
Pediatric ASTHMA-Educator
This project seeks to develop and pilot test the pediatric ASTHMA-Educator mobile application.
- Trial name
- NCT03520881
- Testing
- Pediatric ASTHMA-Educator mobile application
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder
Sensory and Behavioral Aspects With Particular Attention to Food Selectivity in Children With Autism
Brief Summary: Eating problems and in particular food selectivity is a condition that worsens a long-life disorder such as Autism Spectrum Disorder (ASD) , both on an individual level, both on family and social ones .
- Trial name
- NCT06335030
- Where
- 3 sites in Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Fondazione Stella Maris
Polyostotic Fibrous Dysplasia
Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome
This study will evaluate the effectiveness of a new bone injection technique for treating bone disease in patients with polyostotic fibrous dysplasia or McCune-Albright syndrome.
- Trial name
- NCT00001851
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Autism Spectrum Disorder, Anxiety
A Pilot Study of Buspirone for the Treatment of Anxiety in Youth with Autism Spectrum Disorders
The main objective of this exploratory 8-week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT03432065
- Testing
- Buspirone
- Sponsor
- Massachusetts General Hospital
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