Clinical trials: Development Disorders
Autism Spectrum Disorder (ASD), Joint Attention
Joint Attention Processing in Social Threat Scenarios
This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye…
- Trial name
- NCT07582757
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Molar Incisor Hypomineralization
Computer-aided Design/Computer-aided Manufacturing for Mild to Moderate Molar Incisor Hypomineralization Treatment
Molar Incisor Hypomineralization (MIH) is a disease causing a structural defect in the enamel of permanent teeth. The treatment of these teeth consists of the removal of the affected part of the tooth and its reconstitution.
- Trial name
- MIhCFAO (NCT04922177)
- Testing
- Indirect ceramic restoration, Direct restoration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Toulouse
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Transcranial Direct Current Stimulation in Children With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06880159
- Testing
- tDCS with computerized cognitive training
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Preterm Birth, Parent-Child Relations
Epigenetics and Protective Factors in the Preterm Infant
Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in…
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- EPIC (NCT04804280)
- Testing
- DNA methylation of target genes, Functional Magnetic Resonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Pectus Excavatum
Hemodynamic Repercussions of the Correction (Surgical and Non Surgical) of Pectus Excavatum-type Thoracic Deformities
this non-randomized prospective study of 2 longitudinal cohorts (surgical treatment group or orthopedic treatment group), will evaluate the hemodynamic repercussions of the correction (surgical and non surgical) of pectus…
- Trial name
- PECTUS (NCT02174796)
- Testing
- surgical treatment, orthopedic treatment
- Where
- 5 sites in France
- Volunteers
- 41 people
- Sponsor
- Centre Jean Perrin
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Mucopolysaccharidosis IV A, Mucopolysaccharidosis VI
Diagnosis of Mucopolysaccharidosis Disorders in Patients Presenting With Bilateral Hip Disease
BACKGROUND/OBJECTIVE: Quantitative urine screening for mucopolysaccharides (MPS) has been the primary method for detecting mucopolysaccharidoses in children.
- Trial name
- NCT01707433
- Testing
- Enzyme testing
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Language Development Disorders
EMT en Español for Spanish-speaking Toddlers With Language Delays
The goal of the study is to conduct an initial efficacy study of a promising therapist and caregiver-implemented communication intervention to improve language and school readiness skills in low-income Spanish-speaking children…
- Trial name
- NCT04066049
- Testing
- EMT en Español
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Pediatric Growth Hormone Deficiency
A Study to Compare the Experiences of Taking Daily Growth Hormone Injections to Weekly Ngenla in Children With Low Levels of Growth Hormone
The purpose of this study is to learn about: how children stick to taking their injections their experience with the study medicines (Ngenla and daily growth hormone) prescribed to children with low levels of growth hormone.
- Trial name
- NCT06113952
- Testing
- Sharps bin to collect used needles/injections
- Sponsor
- Pfizer
Physical Exercise, Sleep Disturbance
Treatment of Sleep Disturbance in Children With ASD
This RCT study aims to compare effectiveness physical exercise and melatonin supplement on treating sleep disturbance in children with ASD.
- Conditions
- Physical Exercise, Sleep Disturbance, Autism Spectrum Disorder, Melatonin Deficiency
- Trial name
- NCT04878198
- Testing
- Jogging program, Melatonin supplement intervention
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Education University of Hong Kong
Developmental Dysplasia of the Hip (DDH), Congenital Hip Dysplasia
Manual Intervention and Congenital Hip Dysplasia in Infants
Developmental dysplasia of the hip (DDH) is a developmental abnormality of the infant hip in which the acetabulum does not adequately cover the femoral head. Standard conservative treatment commonly includes a Pavlik harness.
- Trial name
- NCT07756814
- Testing
- Manual therapy
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Autism Spectrum Disorders
A Pilot Study of Riluzole Versus Placebo in the Treatment of Children and Adolescents With ASD
This study will examine the potential efficacy and safety of riluzole for core and associated symptom domains of autism and will explore biological markers of safety and treatment response.
- Trial name
- RILISE (NCT01661855)
- Testing
- Riluzole
- Where
- 3 sites in Canada
- Volunteers
- 58 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Child Development Disorder
Craniosacral Therapy Improves Infant Neurodevelopment
Craniosacral exploration and therapy is one of the innovative palpation and treatment techniques in specialized physiotherapy, which can contribute in an efficient, subtle and sudden way to the detection of dysfunctions in the…
- Trial name
- NCT05340049
- Testing
- Academic behavioral intervention of teachers, Therapy sessions
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Clinica Gema Leon
Allergic Disorder
Impact of Microbial Exposure of the Habitat at the Time of Birth on the Development of Allergic Diseases.
In 2001-2002, a longitudinal study on the risk of atopic sensitization in children was conducted by the Pneumo-Allergology and Pediatrics departments of the CHU Saint-Pierre Hospital and at the Neonatology Department of the Queen…
- Trial name
- NCT04189978
- Testing
- Clinical evaluation
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Brugmann University Hospital
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Osteogenesis Imperfecta, Brittle Bone Disorders
Osteogenesis Imperfecta (OI) Quality of Life Survey Pilot Project 2
The purpose of this study is to explore the patient perspective of disease burden in Osteogenesis Imperfecta (OI). Participants will complete a web-based survey of questions which are usually administered within the…
- Trial name
- NCT02793063
- Testing
- Web-based Survey
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of South Florida
Growth, Development
Assisted Exercise in Prematurity; Effects and Mechanisms
Briefly our study is looking at the effects of 4 weeks of assisted exercise on the body composition and neurological/behavioral development of healthy growing premature infants enrolled between the ages of 30-33 weeks.
- Trial name
- NCT00580099
- Testing
- assisted exercise, cuddle
- Where
- United States
- Sponsor
- University of California, Irvine
Autism
A Trial of CM-AT in Children With Autism
The purpose of this study is to determine whether CM-AT is safe and effective in treating the core symptoms of autism.
- Trial name
- CM-AT (NCT00881452)
- Testing
- CM-AT
- Where
- 19 sites in United States
- Volunteers
- 182 people
- Sponsor
- Curemark
Type 2 Diabetes
Taking Action Together- A Diabetes Prevention Program
The purpose of this study was to determine whether once-weekly exposure to a program that fostered self-esteem building, and improvements in nutrition and physical activity behaviors would reduce risk of type 2 diabetes in…
- Trial name
- TAT (NCT01039116)
- Testing
- High Intensity, Low Intensity
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, Berkeley
Molar Incisor Hypomineralization
Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH
This trial will compare the application of Glass Ionomer Cement (GIC) sealant with no-intervention for the most clinically- and cost-effective strategy for managing MIH molars without post-eruptive breakdown, in a school setting…
- Trial name
- MIHMex (NCT03870958)
- Testing
- GIC sealant (GC Fuji TRIAGE®), Control
- Where
- Mexico
- Volunteers
- 195 people
- Sponsor
- Isabel Cristina Olegário da Costa
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