Clinical trials: Development Disorders
Autism Spectrum Disorder
Culturally Adapted Play-Based Behavioural Intervention for Autism
This study compared Culturally Adapted Play-Based Behavioural Intervention (PPBI) and Applied Behaviour Analysis (ABA) for children with Autism Spectrum Disorder (ASD) in semi-rural Tamil Nadu through a double-blinded randomized…
- Trial name
- NCT06859541
- Testing
- Culturally Adapted Play-Based Behavioural Intervention, Applied Behaviour Analysis
- Where
- India
- Volunteers
- 56 people
- Sponsor
- Saveetha University
Autism Spectrum Disorder
Therapeutic Issues for Autism
This study aimed to show the effects of hyperbaric oxygen therapy and/or Risperidone in improving symptoms of autism
- Trial name
- NCT03887754
- Testing
- Risperidone, hyperbaric oxygen therapy, Non specific Multivitamin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Minia University
Learning Disorders
Risk and Resilience Factors in Learning Disabilities Population
The purpose of this study is to report preliminary outcomes of executive function and psychopathology symptoms of a manual-based psychological intervention for adolescents diagnosed with learning disorders- I can succeed (ICS).
- Trial name
- NCT01652651
- Testing
- I Can Succeed ICS
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Emotional Disturbance
Students, Parents, and Teachers On Track: Intervention Development for Youth With Emotional Disturbance
The purpose of the On Track intervention is to address a need raised by a day-treatment school in Lane County: Support for students transitioning from the day-treatment school (Lane School) to their district middle schools.
- Trial name
- OnTrack (NCT01705431)
- Testing
- On Track
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Social Learning Center
Fibrous Dysplasia Of Bone
Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia
Background: Fibrous dysplasia (FD) is a disorder that affects bone growth. Affected bone tissue is weakened, and people with FD are prone to deformities, fractures, and other problems.
- Trial name
- NCT05509595
- Testing
- Burosumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Autism Spectrum Disorder, Neurodevelopmental Disorders
A Smart Toy for Motor Function and Early Assessment of Children With Possible Autism
Autism diagnostic referrals across the UK have doubled within the last five years. Covid-19 has further delayed diagnostic pathways, while innovation has not kept pace in assisting clinical teams with low cost, fast, and…
- Trial name
- Tangiball (NCT04980677)
- Testing
- Tangiball
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sussex Community NHS Foundation Trust
Molar Incisor Hypomineralisation
Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®
Objectives: to compare aesthetic effectiveness of resin infiltration with/without using sodium hypochlorite in managing opacities of MIH on incisors, and to compare parent's satisfaction with results of both application…
- Trial name
- NCT07162077
- Testing
- Sodium hypochlorite 5.25%, ICON resin infiltration Material group in vivo
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Latakia University
Sedentary Behavior, Health Promotion
SWITCH Implementation Effectiveness Trial
The SWITCH (School Wellness Integration Targeting Child Health) project is a multi-component intervention designed to support school wellness programming and contribute to youth obesity prevention.
- Conditions
- Sedentary Behavior, Health Promotion, Overweight and Obesity, Healthy Lifestyle
- Trial name
- NCT04045288
- Testing
- Standard Implementation, Enhanced Implementation
- Where
- United States
- Volunteers
- 1,984 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Cutaneous Lymphoproliferative Diseases, Mycosis Fungoides of Skin (Diagnosis)
Development of an AI-Assisted Diagnostic Tool for Mycosis Fungoides and Other Cutaneous Lymphoproliferative Diseases Using Microscopic Image Analysis: A Training and Validation Study
Cutaneous lymphoproliferative diseases (CLPDs) are a group of skin disorders that range from benign conditions, such as pseudolymphomas, to malignant forms like cutaneous T-cell and B-cell lymphomas.
- Conditions
- Cutaneous Lymphoproliferative Diseases, Mycosis Fungoides of Skin (Diagnosis), T Cell Dyscrasia, PLEVA-PLC Spectrum
- Trial name
- NCT07705386
- Testing
- AI-assisted histopathology image analysis
- Where
- Egypt
- Volunteers
- 463 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)
This single-center, prospective, observational, cross-sectional mechanistic pilot study will evaluate whether polycystic ovary syndrome (PCOS) contributes to hepatic steatosis in adolescent girls independently of adiposity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Hyperandrogenism
- Trial name
- COMPASSpedPCOS (NCT07731373)
- Testing
- Extended Serum Biomarker and Hormonal Panel, Liver Elastography with Controlled Attenuation Parameter, Targeted Genotyping of PNPLA3 rs738409 and HSD17B13 rs72613567
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Iron Deficiency Anemia
Iron Deficiency Anemia and Psychosocial Stimulation
In developing countries, poor nutrition, high morbidity, poverty, poor parental education and stimulation in the home, all detrimentally affect children's development.
- Trial name
- IDA (NCT00668694)
- Testing
- Stimulation
- Where
- Bangladesh
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
PCOS (Polycystic Ovary Syndrome)
Development and Clinical Application of ApoC3 Protein as a Predictive Biomarker for Insulin Resistance in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder causing infertility and miscarriage in women.
- Trial name
- NCT07739953
- Testing
- observational study
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Child, Osteotomy
Iliac Crest Bone Graft Harvesting for Pediatric Pelvic Osteotomy
The iliac crest is one of the most commonly used bone graft sources, especially in pediatric pelvic osteotomy operations for developmental dysplasia of the hip (DDH) and Legg-Calve-Perthes disease.
- Trial name
- NCT04425369
- Testing
- two-sided approaches for iliac crest bone graft
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Yuxi Su
Autism Spectrum Disorder
Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder
This study will consist of a randomized, double-blind, sham-controlled clinical trial at SUNY Upstate Medical University and Mt.
- Trial name
- IPMR ASD (NCT06006637)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder, Intellectual Disability
Vagus Nerve Stimulator for Autism and Other Developmental Disorders
The goal of this flexible single-subject design vagus nerve stimulation (VNS) study is to examine the behavioral, cognitive, and biorhythmic effects of VNS in children and adults with autism and developmental disabilities.
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Autonomic Nervous System, Developmental Disability
- Trial name
- VNS (NCT06259201)
- Testing
- Vagus Nerve Stimulation
- Where
- 2 sites in United States
- Sponsor
- New York State Institute for Basic Research
Intraventricular Hemorrhage Neonatal, Post-hemorrhagic Hydrocephalus
Advanced MRI in IVH
55,000 babies are born prematurely in the UK annually. Bleeding in the fluid spaces of the brain (ventricles) is common after prematurity; in England around 450 babies suffer from severe bleeds every year.
- Trial name
- NCT07412886
- Testing
- Advanced MRI
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Infant Growth, Mothers' Parental Competence
Nursing and Nurturing Premature Infants
The purpose of this study is to determine whether systematic use of the Newborn Individualized Developmental Care Assessment Program (NIDCAP®) improves the neurologic development of children and the parental competence of mothers.
- Trial name
- NCT00388141
- Testing
- NIDCAP
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Dentinogenesis Imperfecta, Amelogenesis Imperfecta
Psycho-social Impact of Amelogenesis and Dentinogenesis Imperfecta
The purpose of this research is to study the impact of dentinogenesis (DI) and amelogenesis (AI) imperfecta on oral quality of life, exposure to bullying and dental anxiety in a population of adolescents.
- Trial name
- AiDiBull (NCT04927962)
- Testing
- Questionnaires
- Where
- 7 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Toulouse
Autism Spectrum Disorders
Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors
The purpose of this research study is to learn about the effects of supplemental intranasal oxytocin as a treatment for improving social difficulties in children and adolescents with autism.
- Trial name
- SOARS-B (NCT01944046)
- Testing
- double Blind Oxytocin Nasal Spray, Open Label intranasal oxytocin
- Where
- 7 sites in United States
- Volunteers
- 290 people
- Sponsor
- Linmarie Sikich
Childhood Mental Disorder
Trial of PCIT-ED in School for Preschoolers in Poverty
A shorted form of the previously tested, Parent Child Interaction Therapy Emotion Development (PCIT-ED) will be conducted with a sample of preschoolers who exhibit symptoms of behavioral problems as rated by teacher.
- Trial name
- PCIT-ED-ACES (NCT04399629)
- Testing
- PCIT-ED, Parenting Wisely
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Washington University School of Medicine
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