Clinical trials: Development and Health
Obesity, Childhood, Child Development
El Sendero: Pathways to Health Study
This project will continue to follow two birth cohorts of mother-infant Latino dyads through a series of new assessments at age 6y, with an emphasis on examining the the role early nutritional exposures, exposures to…
- Trial name
- NCT05551650
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism Spectrum Disorder, Down Syndrome
A Bicycle Training Intervention
The objectives of this study are to 1) demonstrate the effectiveness of the innovative bicycle training program in teaching youth with DS and ASD how to ride a standard two wheel bike, and 2) determine the effects of the…
- Trial name
- NCT02046889
- Testing
- Bicycle Training Intervention
- Where
- 3 sites in United States
- Volunteers
- 155 people
- Sponsor
- University of Michigan
Marfan Syndrome
Marfan Syndrome Moderate Exercise Trial II
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection.
- Trial name
- NCT05809323
- Testing
- Exercise Intervention Group, Control Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Child Development
Zambia Infant Cohort Study - Brains Optimized for Surviving and Thriving
Children exposed to HIV in-utero but uninfected (CHEUs) number 14.8 million globally. In Zambia, an estimated 56,000 CHEUs are born annually, a staggering fraction of the national birth cohort.
- Trial name
- ZICS-BOOST (NCT05119959)
- Testing
- ECD intervention for CHEUs, Usual care for CHEUs
- Where
- 2 sites in United States, Zambia
- Volunteers
- 469 people
- Sponsor
- Boston University
5 Year Old Children Born Prematurely
Early Detection of Developmental Abnormalities of Preterm Infants at 5 Years of Age
The project is a national, prospective, multicenter, interventional pilot project focused on the follow up of 5 year old children that were born prematurely.
- Trial name
- NCT07391527
- Testing
- Pediatric check-up
- Where
- 4 sites in Czechia
- Volunteers
- 210 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Contraceptive Behavior, Self Administration
Impact of Self-Care Family Planning Services on Health and Development in South Sudan (Family Planning Impact Lab)
Since 2019, the International Rescue Committee (IRC) has led family planning programming under the Women's Integrated Sexual Health (WISH) program, funded by the United Kingdom's Foreign, Commonwealth, and Development Office.
- Trial name
- FPIL (NCT07888296)
- Testing
- Self-Managed Contraceptive Care, Standard Family Planning Services (WISH-2)
- Where
- South Sudan
- Volunteers
- 2,736 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Metabolic Disease, Neurological and Mental Health Conditions
Singapore PREconception Study of Long-Term Maternal and Child Outcomes
We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes…
- Conditions
- Metabolic Disease, Neurological and Mental Health Conditions, Genetics Predisposition, Skin Condition
- Trial name
- S-PRESTO (NCT03531658)
- Where
- Singapore
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Infant Malnutrition, Malnutrition in Pregnancy
Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS)
The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi.
- Trial name
- iLiNS-DYAD-M (NCT01239693)
- Testing
- IFA, MMN, LNS
- Where
- Malawi
- Volunteers
- 1,391 people, healthy volunteers welcome
- Sponsor
- Tampere University
Cystic Fibrosis, Siblings
The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis
The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for healthy children and adolescents with siblings with cystic fibrosis (CF).
- Conditions
- Cystic Fibrosis, Siblings, Mental Health, Internet-based Intervention
- Trial name
- NCT06012084
- Testing
- Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Regina
Childhood Obesity, Pediatric Obesity
Multidimensional Intervention in Mexican Schoolchildren
The aims is to evaluate the effects of an multidimensional intervention on the physical-built and social environment around schools and the nutritional status of the school population, through a randomized community trial, in…
- Conditions
- Childhood Obesity, Pediatric Obesity, Childhood Overweight
- Trial name
- NCT07185789
- Testing
- Healthy and Sustainable Eating, Movement behaviors, Psychosocial determinants
- Where
- Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mexican National Institute of Public Health
Rare Disorders
Implementing Dynamic Consent for Rare Disease Patients
The study aims to test on a cohort of rare patients a digital innovative tool to support patients/parents in the informed consent and assent process and to keep up-to-date a lawful informed and dynamic consent and to use samples…
- Trial name
- ConsDinamico (NCT06656247)
- Testing
- Online consenting
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Parent Child Relationships, Parent Child Interactions
Social-emotional Under 4's Screening & Intervention S.U.S.I.
Following an exploratory project, funded by Guys and St Thomas' Charity between September 2010- November 2011, of the first combined mental health screening and intervention project for <5 Children in Care (CiC) in the UK, the…
- Conditions
- Parent Child Relationships, Parent Child Interactions, Child Development
- Trial name
- SUSI (NCT02151955)
- Testing
- Individual
- Where
- United Kingdom
- Volunteers
- 139 people
- Sponsor
- South London and Maudsley NHS Foundation Trust
Early Childhood Development (ECD)
Combined Nutrition and Parenting Study
This study aims to evaluate whether early childhood development is improved by a bundled set of interventions that promote responsive stimulation and improved nutrition by the provision of eggs and dried fish (nutrient-dense…
- Trial name
- BUNDLE (NCT07490899)
- Testing
- Responsive stimulation, female and male caregivers, Food provision and nutrition education
- Where
- 4 sites in Liberia
- Volunteers
- 2,240 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Baby Formula, Growth Equivalence, Neurocognitive Development, Healthy Infants
Growth and Health Outcomes of a New Infant- and follow-on Formula for Healthy Term Infants.
To demonstrate growth equivalence of a Baby formula Test Product when compared to the Control product after 16 weeks. And to demonstrate better neurocognitive development at 52 weeks post-baseline in subjects receiving the Test…
- Trial name
- GAIA (NCT06475521)
- Testing
- Infant Formula
- Where
- 2 sites in Bulgaria, Poland
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Pregnancy, Postpartum Care
Mother and Infant Home Visiting Program Evaluation-Strong Start
Adverse birth outcomes result in significant emotional and economic costs for families and communities. Research suggests that poor birth outcomes are influenced by a variety of social, psychological, behavioral, environmental…
- Conditions
- Pregnancy, Postpartum Care, Infant Development
- Trial name
- NCT02076204
- Testing
- Home visiting
- Where
- United States
- Volunteers
- 1,059 people
- Sponsor
- MDRC
Preterm Infants, Term Infants
The Intestinal Innate Immune System in Newborns. Development and Inflammation in Health and Disease
The goal of this observational study is to determine the normal development of the human intestinal immune system in premature and mature neonatal life and to determine the pathophysiology behind life-threatening gastrointestinal…
- Conditions
- Preterm Infants, Term Infants, Necrotising Enterocolitis, Atresia; Bowel
- Trial name
- INTINE (NCT06092463)
- Where
- 2 sites in Denmark
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Internet-Based Intervention
Evaluation of the First Pathways Game on Parent-child Interactions and Development for Vulnerable Children
Children's brains develop quickly in the first three years of life and are particularly sensitive to their environment. Adverse experiences, such as exposure to abuse and neglect, can increase children's risk for behavioral…
- Trial name
- NCT04902404
- Testing
- First Pathways Game
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Vestibular Migraine
Health Belief Model Scale Development for Disability and Abilities in Vestibular Migraine Patients
Vestibular migraine (VM) is a neurological condition characterized by recurrent episodes of dizziness, imbalance, and migraine-related symptoms. Individuals' responses to health problems are influenced by their health beliefs.
- Trial name
- NCT07469748
- Testing
- Vestibular Migraine Education / Awareness Session
- Where
- Turkey (Türkiye)
- Volunteers
- 213 people
- Sponsor
- Istanbul Aydın University
Prodromal Schizophrenia, Psychosis
Feasibility Trial of a Lifestyle Intervention for CHR-P
The present study will assess the feasibility and social validity of an adjunctive health promotion group for youth and clinical high risk for psychosis (CHR-P).
- Conditions
- Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
- Trial name
- NCT05532683
- Testing
- Health Behaviors Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Los Angeles
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong