Clinical trials: Developmental Disorder
Osteoarthritis, Arthritis
A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup
This is a multi-centre, prospective post marketing surveillance study to assess mid-term performance of the Mpact cup in subjects requiring primary total hip arthroplasty.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT02196818
- Testing
- Mpact Acetabular Shell
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Autism Spectrum Disorder
Effect of a Casein and Gluten Free Diet in Mexican Children With Autism Spectrum Disorder
Assess the effect of a casein-free and gluten-free diet on gastrointestinal symptoms, clinical variables, and the composition of the intestinal microbiota in Mexican children with autism spectrum disorder.
- Trial name
- NCT06556290
- Testing
- Gluten free and casein free diet
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- University of Guadalajara
Chromosome Disorders
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and…
- Trial name
- NCT00064597
- Where
- 5 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dyslexia, Developmental
Developmental Dyslexia and Remediation Methods
At least, three theoretical frameworks are currently involved in therapeutic research in developmental dyslexia. Each theoretical framework relies on the type of underlying cognitive processes that is viewed as impaired: 1°)…
- Trial name
- DDMR (NCT04028310)
- Testing
- Phonological, Visual-attention
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Fondation Lenval
Cystic Fibrosis, Inflammation
Connexin Genotypes in Cystic Fibrosis
Background: There is wide variety in lung disease phenotype for the delta F508 (homozygous) genotype. A leukocyte driven inflammation is most important for the pathogenesis of pulmonary disease in CF.
- Trial name
- NCT04242420
- Testing
- Genotyping, Lung function, Microbiology
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 300 people
- Sponsor
- University Childrens' Hospital (Zentrum für Kinderheilkunde des Universitätsklinikum Bonn)
Autism Spectrum Disorder
Building Better Bridges Randomized Control Trial
In this study, the investigators will randomize 20 families per site (across 4 sites) to be in the BBB Transition Passport Only Group or BBB Intervention Group.
- Trial name
- (AIR-B3) (NCT03445520)
- Testing
- Intervention Coaching Group
- Where
- 3 sites in United States
- Volunteers
- 375 people
- Sponsor
- Health Resources and Services Administration (HRSA)
Infant and Young Child Feeding
Standardized Application of Feeding Evaluations Using SMART Tool
Premature and medically complex infants have delayed development of oral feeding skills, leading to prolonged hospitalization, costs, and family stress.
- Trial name
- SAFEST (NCT07136610)
- Testing
- SMART Tool
- Where
- 14 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Wake Forest University Health Sciences
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Autism Spectrum Disorder
SOCIAL: Adaptation and Validation of the In-person PEERS® Program for Adolescents With Autism.
Autism Spectrum Disorder (ASD) falls under the category of high complexity disorders which, in most cases, accompany individuals throughout their entire life with significant impacts and costs for individuals, their families, and…
- Trial name
- NCT07207213
- Testing
- PEERS, Control
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Fondazione Stella Maris
Acquired Immunodeficiency Syndrome
Intervention for HIV-Positive Black Young Men Who Have Sex With Men (YMSM)
This study involves conducting formative research to develop a culturally appropriate secondary prevention intervention for HIV-positive Black young men who have sex with men (B-YMSM).
- Trial name
- NCT01502618
- Testing
- Focus Group
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Molar Incisor Hypomineralization, Asthma in Children
Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives
The aim of this study is to assess the prevalence of molar incisor hypo mineralization among children who have been treated with asthmatic drugs during the first three years of life.
- Trial name
- NCT04103710
- Where
- Egypt
- Volunteers
- 167 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
The Effect of CrossFit Kids on Social Skills in Children With Autism Spectrum Disorder (CrossFit KAMP)
The Centers for Disease Control and Prevention estimates that 1 in 59 U.S. children have been diagnosed with an autism spectrum disorder (ASD).
- Trial name
- CrossFit KAMP (NCT03693313)
- Testing
- CrossFit Kids exercise program
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Davis
Mental Disorders, Healthy Control
Psychiatric Multi-omics and Neuroimaging Project
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three.
- Trial name
- PMNP (NCT06580860)
- Testing
- Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
- Where
- China
- Volunteers
- 1,899 people, healthy volunteers welcome
- Sponsor
- mingjun Zhong
Autism Spectrum Disorder
Smartphone-Based Neurobehavioral Assessments as a Diagnostic Aid in Autism
Retrospective case-control study to assess the diagnostic accuracy in autism spectrum disorder (ASD) of a new smartphone-based platform designed to conduct neurometric evaluations by measuring facial and behavioural reflexes.
- Trial name
- NCT06497218
- Testing
- Blinklab diagnostic device
- Where
- Morocco
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Developmental Disabilities
Recombinant Human Erythropoietin Improve Neurodevelopmental Outcomes in Extremely Preterm Infants
In the ELGAN (Extremely Low Gestational Age Newborn) study, abnormal brain structure and function were associated with intermittent or sustained systemic inflammation (ISSI).
- Trial name
- EPO (NCT02745990)
- Testing
- Recombinant human erythropoietin, Normal saline
- Volunteers
- 440 people
- Sponsor
- Huiqing Sun
Autism Disorder, ASD
GENES AND AUTISM - Induced Pluripotent Stem Cells
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction and verbal and non-verbal communication (DSM-5, 2013), affecting approximately 2% of the general population.
- Trial name
- IPSC (NCT07311213)
- Testing
- Blood Sample : isolation of peripheral blood mononuclear cells (PBMCs)
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism
Prebiotic Intervention for Autism Spectrum Disorders
The purpose of this study is to determine the effect of a prebiotic (BGOS) on gut microbiota and metabolites in children with autism spectrum disorders.
- Trial name
- NCT02720900
- Testing
- B-GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Clasado Limited
Immune System Disorder, Preterm
Preterm Immune System Development and Response to Immunization
In this study the response to vaccination and development of the immune system in very preterm infants upon the current vaccination schedule will be compared to healthy term infants.
- Conditions
- Immune System Disorder, Preterm, Vaccination Failure
- Trial name
- PRIMI (NCT05266664)
- Where
- 7 sites in Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Autism Spectrum Disorder
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorders
This study is a prospective, multicenter, randomized, single-blind controlled trial to enroll 200 children with autism spectrum disorders (ASD).
- Trial name
- NCT05927792
- Testing
- repeated transcranial magnetic stimulation (continuous theta-burst stimulation)
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Executive Function Deficits (EFD)
Unstuck-Early Childhood Effectiveness & Implementation Trial
The goal of this clinical trial is to learn if a new school-based, Tier 2 (selective) cognitive-behavioral intervention called Unstuck and On Target for Early Childhood (Unstuck-EC) can treat executive function deficits in young…
- Trial name
- NCT07832344
- Testing
- Unstuck and On Target for Early Childhood
- Volunteers
- 90 people
- Sponsor
- Children's National Research Institute
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