Clinical trials: Diabetes Treatment (Pilot Study)
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Diabetes Mellitus, Type I, Program Evaluation
Evaluation of the Impact of a Therapeutic Education Program for Children With Type 1 Diabetes
The needs of children and teens with type 1 diabetes are very specific and different from the adults with type 1 diabetes. Many organizations such as the World Health Organization or the International Society for Pediatric and…
- Conditions
- Diabetes Mellitus, Type I, Program Evaluation, Therapeutic Education, Children
- Trial name
- PROGETE (NCT02970357)
- Testing
- DIAPASON Questionnaire, WHO-5
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Diabetic Retinopathy
Triamcinolone Acetonide Injections to Treat Diabetic Macular Edema
This study will evaluate which of the three following treatment options is better for diabetic macular edema: laser alone, steroid injection alone, or steroid injection followed by laser.
- Trial name
- NCT00231023
- Testing
- Peribulbar Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Cystic Fibrosis Related Diabetes, Pancreatic Insufficiency
Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis
The purpose of this study is to provide the necessary data and experience to design a larger, full scale clinical trial to determine if a certain medicine (repaglinide), which increases the amount of insulin secreted by the…
- Trial name
- NCT00763412
- Testing
- repaglinide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Arbelaez, Ana Maria
Type 1 Diabetes, Monogenic Diabetes
Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study
The purpose of this study is to evaluate the efficacy of adding oral hypoglycemic agents (OHA) to existing insulin treatment in monogenic variant carriers of the Joslin 50-Year Medalist Study ("Medalists"), who are characterized…
- Trial name
- NCT04409795
- Testing
- Metformin Extended Release Oral Tablet, Sitagliptin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Joslin Diabetes Center
Hyperinsulinism, Diabetes
Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes
This is a pilot study designed to determine if the bihormonal bionic pancreas provides improved blood glucose control, compared to the current standard of care, in individuals with hyperinsulinism who developed diabetes after…
- Conditions
- Hyperinsulinism, Diabetes, Pancreatic Diseases, Pancreatectomy; Hyperglycemia
- Trial name
- NCT03303196
- Testing
- Bihormonal Bionic Pancreas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus, Insulin-Dependent
Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)
Within 4 weeks after diagnosis of type 1 diabetes, 10 subjects (pubertal males, 12-17 years old) will be randomized to either receive multiple daily injection (MDI) using Lantus insulin, or continuous subcutaneous insulin…
- Trial name
- NCT00357890
- Testing
- Insulin pump therapy, Multiple daily injections using insulin glargine + rapid acting analog
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nemours Children's Clinic
Childhood Cancer Survivors Treated With Abdominal Radiation
Assessing Insulin Sensitivity and Diabetes Risk in Childhood Cancer Survivors Treated With Abdominal Irradiation
The purpose of this study is to better understand the risk factors and causes of diabetes in people who received radiation to the abdomen as children.
- Trial name
- NCT02248779
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Type 1 Diabetes Mellitus
Pramlintide and Fiasp Closed-Loop With a Simple Meal Announcement
The aim of this pilot study is to generate preliminary data of (i) Fiasp-plus-Pramlintide closed-loop system with a simple meal announcement, compared to (ii) Fiasp-alone closed-loop system with full carbohydrate counting, in…
- Trial name
- NCT03993366
- Testing
- Fiasp+Pramlintide Closed-Loop System, Fiasp Closed-Loop System
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McGill University
Syndrome
Leptin to Treat Severe Insulin Resistance - Pilot Study
This pilot study will evaluate the safety and effectiveness of leptin therapy in two children with severe insulin resistance syndrome.
- Trial name
- NCT00027456
- Testing
- Leptin A-100
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1
Evaluation of a Booster Administration of GAD-alum (Diamyd®) in Individuals With Type 1 Diabetes
The objective of the study is to evaluate the feasibility and safety of administering a 4th or 5th intralymphatic booster dose of GAD-alum (Diamyd®) to T1D patients carrying HLA DR3-DQ2, who have earlier been treated with three…
- Trial name
- NCT05351879
- Testing
- GAD-alum (Diamyd) 40 μg/mL
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Linkoeping University
Type 1 Diabetes, Diabetes Mellitus
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
The primary aim of this pilot randomized controlled trial is to determine if the integration of a Community Health Worker (CHW) into the healthcare team of children with newly diagnosed type 1 diabetes is associated with an…
- Conditions
- Type 1 Diabetes, Diabetes Mellitus, Psychosocial Problem, Compliance, Patient
- Trial name
- NCT04238949
- Testing
- Community Health Worker added to diabetes team
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital of Philadelphia
Hypotension
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants
Low blood pressure or hypotension is a very important problem that is often seen in premature babies, especially those with low birth weight.
- Trial name
- NCT01318278
- Testing
- Dopamine, Arginine Vasopressin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor College of Medicine
Diabetes
Evaluation of Neurodevelopmental Trajectories in Children According to the Glycemic Profile Associated With Early Treatment Using an Automated Delivery System in Children With Type 1 Diabetes
ore than half of all new cases of type 1 diabetes (T1D) are diagnosed within the first decade of life. It has been reported that early onset of this disease may be associated with a decline in cognitive performance in adulthood…
- Trial name
- PROCEDE (NCT06461065)
- Testing
- AIDS, Brain MRI
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cystic Fibrosis, Diabetes Related Cystic Fibrosis
Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis
Patients with end-stage cystic fibrosis (CF) and severe CF-related diabetes (CFRD) may benefit from combined lung-pancreatic islet transplantation.
- Conditions
- Cystic Fibrosis, Diabetes Related Cystic Fibrosis, Insulin-dependent Diabetes
- Trial name
- PIM (NCT01548729)
- Testing
- Combined pancreatic islet and lung transplantation
- Where
- 28 sites in France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Type 1 Diabetes Mellitus
Umbilical Cord Blood Infusion to Treat Type 1 Diabetes
While this study is now completely enrolled, we do hope to develop a "next generation" cord blood based study sometime in early 2009.
- Trial name
- NCT00305344
- Testing
- Autologous Umbilical Cord Blood Transfusion, Cord blood
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Diet, Healthy, Health Behavior
A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina
Increasing fruit and vegetable (FV) intake, and reducing saturated fat, salt, and added sugar are central lifestyle recommendations in the Dietary Guidelines for Americans to prevent chronic disease.
- Conditions
- Diet, Healthy, Health Behavior, Blood Pressure, Diabetes Mellitus Risk
- Trial name
- NCT07221045
- Testing
- PhytoRx Families: A Pilot Test to Address Food Security in Rural North Carolina
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University