Clinical trials: Diabetes Treatment (Pilot Study)
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Impact of ACT-based Interventions on Diabetes-related Outcomes
Individuals with insulin-treated diabetes can experience psychological difficulties associated with living with and managing the condition.
- Trial name
- NCT04028427
- Testing
- Values-plus-goals intervention, Mindfulness-based intervention
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Sophini Logeswaran
Orthostatic Hypotension, Diabetes
Insulin Therapy and Falls Due to Orthostatic Hypotension
In the proposed study, the investigators examine in older adults with Type 2 diabetes the impact of beginning insulin therapy on the orthostatic drop in blood pressure as well as the response of arterial blood pressure and…
- Conditions
- Orthostatic Hypotension, Diabetes, Syncope
- Trial name
- NCT01914146
- Testing
- Insulin, No Insulin
- Where
- Canada
- Sponsor
- University of British Columbia
Diabetic Retinopathy, Vitreous Hemorrhage
Use of Intravitreal Ranibizumab in the Treatment of Vitreous Hemorrhage
Primary Objective: To investigate the effectiveness of intravitreal applications of 0.5 mg Lucentis (ranibizumab) in patients with vitreous hemorrhage due to proliferative diabetic retinopathy.
- Trial name
- NCT01824043
- Testing
- intravitreal ranibizumab injections
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Regional de São José - Dr. Homero de Miranda Gomes
Diabetic Macular Edema
Pilot Study for the Evaluation of Intravitreal Infliximab in the Treatment of Diabetic Macular Edema
The purpose of this study is to determine if intravitreal infliximab is a safe and effective treatment for macular edema secondary to diabetes.
- Trial name
- NCT00959725
- Testing
- Infliximab (intravitreal, 2.0mg/0.05ml)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy)
OCT-based DAPT Cessation in HBR Patients
This study investigates whether patients with diabetes mellitus (DM) and a high risk of bleeding can safely stop dual antiplatelet therapy (DAPT) earlier than usual after receiving a special type of stent called a polymer-free…
- Conditions
- High Bleeding Risk Patients, DAPT(Dual Antiplatelet Therapy), Coronary Artery Disease, Diabetes Mellitus
- Trial name
- NCT07238764
- Testing
- Optical Coherence Tomography-based early DAPT discontinuation
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Depression, Diabetes Mellitus Type 2
Pilot Study of a Self-help Intervention for Depression in Patients With a Chronic Disease
A feasibility pilot trial of the self-help, "Cognitive behavioural therapy" based "Living Life to the Full" Materials for use by patients with diabetes type 2 and / or coronary heart disease.
- Conditions
- Depression, Diabetes Mellitus Type 2, Coronary Heart Disease
- Trial name
- NCT00854984
- Testing
- Living Life to the Full
- Where
- 2 sites in United Kingdom
- Volunteers
- 49 people
- Sponsor
- University of Edinburgh
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
Effects of Olfactory Training on the Brain Function in T2DM Patients With Mild Cognitive Impairment
This is a prospective, randomized, open label, parallel, 4-month study to explore and evaluate the therapeutic effects of olfactory training on the cognitive function, olfactory function, and odor-induced brain activation in T2DM…
- Trial name
- NCT06327633
- Testing
- Olfactory Training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Neuropathies
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
The "Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot study (CBD-DPN1)" is a double-blinded, placebo-controlled, crossover pilot study evaluating the efficacy of Cannabidiol (CBD) and full-spectrum CBD…
- Trial name
- CBD-DPN1 (NCT07298408)
- Testing
- Cannabidiol (CBD) oral solution, Full-Spectrum CBD hemp extract oral solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida A&M University
Hypogonadism, Peripheral Vascular Disease
Testosterone for Peripheral Vascular Disease
There is increasing evidence of the linkage of type 2 diabetes with low testosterone levels in men.
- Conditions
- Hypogonadism, Peripheral Vascular Disease, Type 2 Diabetes
- Trial name
- NCT00504712
- Testing
- Testosterone, saline
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Barnsley Hospital
Diabetes Mellitus, Type II, Periodontitis
Impact of Periodontal Therapy on Patients With Diabetes
With poorly controlled diabetes, periodontal status often worsens, and with severe periodontal conditions there is often poorer glycemic control.
- Trial name
- DMRCT (NCT04830969)
- Testing
- Chlorhexidine gluconate oral rinse, Scaling & Root Planing, Soft Picks
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- State University of New York at Buffalo
Diabetes Mellitus, Type 2
MBCT for DM Distress: a Pilot Qusai-experimental Study
Background: Diabetes-related distress (DRD) is very common among people with type II diabetes mellitus (DM). DRD led to poorer DM control and may led to adverse prognosis.
- Trial name
- NCT03484689
- Testing
- Mindfulness-based cognitive therapy MBCT
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Type 2, Obesity
I-care: Stimulating Self-management in Patients With Type 2-diabetes
The overall objective of this pilot study is to develop a cost-effective treatment methodology delivered outside of traditional clinical setting, and based on modern technology for patients with diabetes type 2 also suffering…
- Trial name
- I-care (NCT01297049)
- Testing
- Cognitive behavior therapy (CBT)
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo Metropolitan University
Type 2 Diabetes Mellitus, Fear of Hypoglycemia
Effects of a Health Intervention on Fear of Hypoglycemia : a Pilot Study
The purpose of this study was to construct a Fear of Hypoglycemia(FoH) intervention program for type 2 diabetic patients based on the Behaviour Change Wheel (BCW) theory and to investigate the feasibility, acceptability, and…
- Conditions
- Type 2 Diabetes Mellitus, Fear of Hypoglycemia, Health Education, Impaired Awareness of Hypoglycemia
- Trial name
- NCT06197360
- Testing
- Based on BCW Theory of Health Education, General diabetes health education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Type 1 Diabetes
A Learning Algorithm for MDI Individuals With Type 1 Diabetes to Adjust Recommendations for High Fat Meals and Exercise Management
McGill artificial pancreas lab has developed a learning algorithm using a reinforcement learning approach to adjust basal and bolus recommendations for high-fat meals and exercise management for individuals with type 1 diabetes…
- Trial name
- NCT05041621
- Testing
- Sensor augmented MDI therapy plus mobile application
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University
Osteoarthritis, Knee, Hypertension
The Clinical Impact of Diet on Medical Conditions Treated Within Bundled Payment Models: a Pilot Study
Diet interventions (e.g., low-energy diets) are recommended as a treatment for obesity, obese patients with osteoarthritis, hypertension (HTN), and type 2 diabetes (T2D).
- Conditions
- Osteoarthritis, Knee, Hypertension, Type 2 Diabetes, Obesity
- Trial name
- NCT05735873
- Testing
- Low-energy diet
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Diabetes Mellitus, Type 2
A Research Study to Understand How People With Type 2 Diabetes Take Ozempic® and if the Ozempic®App Helps Them Stay on This Treatment
This study looks at how participants with type 2 diabetes take Ozempic® and if the Ozempic® app helps participants to stay on this treatment. Participants will already be prescribed with Ozempic® by the study doctor.
- Trial name
- NCT06478550
- Testing
- Semaglutide
- Where
- 6 sites in Greece
- Volunteers
- 304 people
- Sponsor
- Novo Nordisk A/S
Diabetes
Infrared Wraps Effect on Oxygenation of Diabetics Arm, Feet and Lower Leg
This study seeks to prove that wraps manufactured with infrared textile are capable of augmenting peripheral circulation in the lower legs, arm and feet of participants with Diabetes Mellitus.
- Trial name
- NCT04460612
- Testing
- Active IR sock
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Yale University
Hypertension, Diabete Mellitus
Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts
The goal of this clinical trial is to learn whether AI-enabled, nurse-led treatment planning can improve the quality of clinical reasoning and management compared with standard physician-led care in adult primary care patients…
- Conditions
- Hypertension, Diabete Mellitus, Breathlessness, Fever
- Trial name
- NCT07432893
- Testing
- AI-enabled clinical decision support tool (software) used by nurses, Physician consultation
- Where
- 2 sites in India
- Volunteers
- 736 people
- Sponsor
- Sarah Nabia
Diabetes Mellitus Type 2, Hyperglycemia
Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia
Saxagliptin + Metformin XR (S+M) will be effective in stabilizing blood glucose (BG) levels in patients with newly diagnosed type 2 diabetes (T2DM) with severe hyperglycemia (BG levels 300 to 450 mg/dl) and glucose toxicity and…
- Trial name
- NCT01267448
- Testing
- Glipizide XL, Saxagliptin + Metformin XR, Metformin XR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cook County Health