Clinical trials: Diabetes type1
Type 1 Diabetes
Diabetes Transition Coordinator Study
The goal of this interventional study is to assess the effects and evaluate the implementation of a pediatric to adult care transition intervention in youth with T1D on clinical, patient-reported, and implementation outcomes…
- Trial name
- NCT06300047
- Testing
- Non-Medical Transition Coordinator
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 1
Evaluation of Novel Trend Arrow Adjustment Tool for Diabetes Patients Using Continuous Glucose Monitoring to Guide Insulin Bolus Adjustment (TAAT Study)
Continuous glucose monitoring (CGM) provides up to 288 blood glucose levels per day, updated every 5 minutes and displayed in real-time on the insulin pump, which can be used to enhance delivery of insulin through pump therapy.
- Trial name
- TAAT (NCT02064647)
- Testing
- Trend Arrow Adjustment Tool, 10/20% bolus adjustment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Diabetes Mellitus, Type 1, Self-Management
Promoting Self-management Behaviors in Adolescents With Type 1 Diabetes, Using Digital Storytelling
The aim of this study was to evaluate the effects of digital storytelling on the Self-Management behavior of adolescents with type 1 diabetes (TID).
- Trial name
- NCT04608058
- Testing
- Digital storytelling training, Routine training
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Nahid Zarifsanaiey
Diabetes Mellitus, Type 1
Omega-3 Fatty Acids Supplementation Improves Early-stage Diabetic Nephropathy and Subclinical Atherosclerosis in Pediatric Patients With Type 1 Diabetes
The investigators conducted this randomized-controlled trial to assess the effect of oral omega-3 supplementation on glycemic control, lipid profile, albuminuria level, kidney injury molecule-1 (KIM-1) and carotid intima media…
- Trial name
- NCT05980026
- Testing
- oral omega-3 fatty acids supplementation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Type 1 Diabetes Mellitus
Basic Hematological Parameters and Coagulation Profile in Type 1 Diabetic Children
Diabetes mellitus is a group of chronic metabolic diseases characterized by hyperglycemia .Type 1 diabetes is a heterogeneous disease related to the destruction of pancreatic beta cells and is a result of absolute lack of insulin…
- Trial name
- NCT06897904
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes Mellitus
Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus
This is a multicenter, randomized, partial-blinded, five-arm, placebo-controlled study of human plasma-derived alpha1-proteinase inhibitor (alpha1-PI) in children (ages 6-11 years old) and teens/adults (ages 12-35 years old) with…
- Trial name
- NCT02093221
- Testing
- 180 mg/kg Alpha1-PI, 90 mg/kg Alpha1-PI
- Where
- 36 sites in United States
- Volunteers
- 76 people
- Sponsor
- Grifols Therapeutics LLC
Type 1 Diabetes, HbA1c
Steno Diabetes Dialogue Cards Teaching on Group Education on Blood Sugar Control in Adolescents With Type 1 Diabetes
The Type 1 diabetes is the autoimmunity system produces the antibody which starts to attack the B lymphocytes while the autoimmunity is also been attacked.
- Conditions
- Type 1 Diabetes, HbA1c, Self-management
- Trial name
- NCT05394532
- Testing
- Education
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Type 1
Effects of Structured Group Education on Quality of Life and Glycemic Control in Type 1 Diabetes
Patients with type 1 diabetes aged 15-65 years without major complications will be randomized either to usual care or to a structured group education program, with 6 four-hour weekly interactive sessions devoted to diabetes…
- Trial name
- NCT02443532
- Testing
- Structured group education, Individual education
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Type 1 Diabetes
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question[s] it aims to answer are: Does it reduce stress on the cells that make insulin? Does it preserve what is left…
- Trial name
- TADPOL (NCT05594563)
- Testing
- DFMO
- Where
- 7 sites in United States
- Volunteers
- 74 people
- Sponsor
- Emily K. Sims
Diabetes
Acceptance and Value Based Methods in Increasing Wellbeing of Adolescents With Type 1 Diabetes
The aim of the study is to study how using acceptance and value based group intervention helps the wellbeing of teenagers with type in diabetes.
- Trial name
- NCT03825562
- Testing
- acceptance and commitment therapy, ACT
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Central Finland Hospital District
Type I Diabetes
Anti-IL-1 Treatment in Children Diabetic Keto-Acidosis (DKA) at Diagnosis of Type 1 Diabetes
This is a randomized, double-blind, placebo-controlled phase 2 study. Specific aim is to evaluate feasibility and safety of anti-IL-1 (interleukin 1) treatment in the course of standard therapy for diabetic ketoacidosis in…
- Trial name
- NCT01477476
- Testing
- Anakinra
- Where
- 2 sites in United States
- Sponsor
- University of Colorado, Denver
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Type 1 Diabetes Mellitus, Diabetic Ketoacidosis
Biomarkers of Acute Organ Injury in Pediatric Newly Diagnosed Type 1 Diabetes
Diabetic ketoacidosis (DKA) is a severe metabolic complication in children with newly diagnosed type 1 diabetes mellitus (T1DM) and may be associated with early injury of vital organs such as the kidneys and the heart.
- Trial name
- NCT07483879
- Testing
- Biomarker and Echocardiographic Assessment
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Type 1 Diabetes
Multi-center Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control at Home
The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting.
- Trial name
- NCT02748018
- Testing
- 670G and 770G Insulin Pump, Subject's Current Diabetes Therapy
- Where
- 36 sites in United States, Canada and 7 more
- Volunteers
- 959 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes Mellitus
Constructed Intervention by Home and School Diabetes Nurse Visits on Diabetic Control of Children With Type I Diabetes
The investigators assume that an intervention program that includes home visits and trainings of diabetes' nurse and dietitian will lead to an improvement of the patients' metabolic balance, a decrease in complications' rate, a…
- Trial name
- NCT01382459
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
Diabetes Mellitus, Healthy
Genetic Influence on Susceptibility to Type 1 Diabetes Mellitus
Type 1 diabetes mellitus is an autoimmune disease in which the body's immune cells attack the insulin-producing cells of the pancreas.
- Trial name
- NCT00001985
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes
A Longitudinal, Observational Study Comparing Real-World Experiences of Teplizumab-Treated and Untreated Participants With Stage 2 Type 1 Diabetes in the United States
This study is an observational, longitudinal, non-interventional real-world study in the United States. The study is meant to describe the experience of participants with a history of stage 2 type 1 diabetes who have been infused…
- Trial name
- TEPLI-QUEST (NCT07260110)
- Testing
- Teplizumab
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Sanofi
Diabetes, Diabetes Mellitus, Type 1
Within-subject Variability of Insulin Detemir in Children and Adolescents With Type 1 Diabetes
This trial is conducted in Europe. The aim of this trial is to compare the within-subject variability of the pharmacokinetic profiles of insulin detemir and insulin glargine in children and adolescents with type 1 diabetes.
- Trial name
- NCT01497574
- Testing
- insulin detemir, insulin glargine
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1
AbATE Follow-Up Study
This study proposes to conduct a non-interventional, multi-center trial that will look at C-peptide results from one or two Mixed Meal Tolerance Tests (MMTT) in participants who received anti-CD3 treatment or placebo on the Abate…
- Trial name
- NCT02067923
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
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