Clinical trials: Diagnostic Imaging Utilization
Stage I Breast Cancer, Stage II Breast Cancer
Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
This clinical trial will enroll up to 130 adult women with a confirmed diagnosis of clinical stage 1 or 2 breast cancer who are undergoing breast cancer surgery with lumpectomy or mastectomy and planned axillary sentinel node…
- Trial name
- NCT02419807
- Testing
- Indocyanine Green Solution, Technetium Tc-99m Sulfur Colloid, Lymphoscintigraphy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Case Comprehensive Cancer Center
Healthy
Use of [18F]FECNT in Positron Emission Tomography
This study will examine the use of a new radioactive tracer called [18F]FECNT in positron emission tomography (PET) scanning for measuring dopamine transporter (DAT) in the brain.
- Trial name
- NCT00083629
- Testing
- PET
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Craniopharyngioma
1.5T Intraoperative MR Imaging in Craniopharyngiomas
Purpose of this study is to investigate whether intraoperative imaging using a 1.5T MRI in craniopharyngioma surgery is useful in order to increase the rate of complete tumor removal.
- Trial name
- NCT01206543
- Testing
- Intraoperative imaging using 1.5T MRI
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Hofmann, Bernd, M.D.
Utilization, Laboratory, Hospital
Effect of Norms on Laboratory and Imaging Testing (ENLITen)
Studies suggest that some laboratory tests ordered for hospitalized patients are duplicative or have limited value. This study will evaluate a normative feedback intervention to reduce overuse of laboratory tests for hospitalized…
- Trial name
- ENLITen (NCT02330289)
- Testing
- Normative report card
- Volunteers
- 154 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Use of Compressed Sensing in Breast MRI
Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different…
- Trial name
- COMPRIM (NCT02826369)
- Testing
- 3.0 Tesla in Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Institut de Cancérologie de Lorraine
Supraventricular Tachycardia
Using Non-Fluoroscopic Imaging Devices to Decrease Radiation Exposure During Ablation of Supraventricular Tachycardia
The purpose of this study is to determine whether the additional use of non-fluoroscopic imaging modalities can decrease the use of radiation exposure during standard ablation procedures for supraventricular tachycardia (SVT) in…
- Trial name
- NCT00979303
- Testing
- Intracardiac echocardiography and 3D navigational system
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Celiac Disease
Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults
The goal of this research is to conduct a pilot clinical study to image Celiac disease characteristic mucosal lesions and compare Optical Frequency Domain Imaging (OFDI) images to histologic evaluation in children, adolescents…
- Trial name
- NCT01439035
- Testing
- MGH OFDI Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Orthodontics, Malocclusion
The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics
Research questions: 1. Will the panoramic images derived from cone beam CT data give better diagnostic ability than conventional panoramic radiographs? 2.
- Conditions
- Orthodontics, Malocclusion, Impacted Tooth, Cephalometry
- Trial name
- NCT01246830
- Testing
- Panoramic radiograph, Cephalometric radiograph, Cone-beam computed tomography (CBCT)
- Where
- 2 sites in Belgium
- Volunteers
- 32 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cannabis Use, Depression
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
- Trial name
- Cann-Teen (NCT06941298)
- Testing
- Neuroimaging Investigation
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Miami
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Diagnostic Imaging Utilization
Effect of Diagnostic Imaging Utilization Reports
Diagnostic imaging (DI) tests (for example, x-ray tests, ultrasounds, CT scans, or MRIs) are used by health care providers to help diagnose patient illness, but decisions regarding when these tests should be ordered are…
- Trial name
- NCT02917837
- Testing
- Usual QCNL DI utilization report, New DI utilization report, Detailing
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Magnetic Resonance Imaging, Image Enhancement
Drug Use Investigation of Gadovist.
The objectives of this study are to investigate the safety and effectiveness of Gadovist.
- Trial name
- NCT02540967
- Testing
- Gadobutrol (Gadavist/Gadovist, BAY86-4875)
- Where
- Japan
- Volunteers
- 3,357 people
- Sponsor
- Bayer
Multiple Myeloma
Rationale for Cytogenetic Risk Stratification by Imaging Flow Cytometry in Multiple Myeloma
A pioneer study demonstrated a proof of concept for IS-FISH with the new ISX technology. This state of the art technology has been recently acquired by the CHU of Amiens.
- Trial name
- CIF-PM (NCT03983486)
- Testing
- Imaging flow cytometry in multiple myeloma
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Scaphoid Fracture
Pilot Study to Test the Feasibility of the Use of MRI in Suspected Scaphoid Fractures
This pilot study aims to test the feasibility and work flows associated with using MRI as the initial imaging modality in the investigation of patients presenting with suspected scaphoid fracture.
- Trial name
- NCT02605096
- Testing
- MRI, X-ray
- Volunteers
- 10 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Solid Cancers
68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study
This project aims to monitor the innocuity/safety profile of cyclotron-produced [68Ga]-PSMA-617 PET imaging in PSMA-expressing cancers. It is a single-site, pragmatic, non-randomized and open-label study, with no control group.
- Trial name
- NCT05228106
- Testing
- [68Ga]-PSMA-617
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Respiratory Disorders
Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of children and adults and in adults and also in children with…
- Trial name
- HPXeMR (NCT02272049)
- Testing
- Hyperpolarized 129 Xenon
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Magnetic Resonance Imaging (MRI), Cardiac Pacing
Evaluation of Approved Pacing Lead (Model 5076) for Use in MRI Environment
The purpose of this study is to test the safety and effectiveness of the Medtronic CapSureFix Novus Model 5076 lead when patients are implanted with the Medtronic Advisa MRI pacemaker and undergo an MRI scan.
- Trial name
- NCT01755143
- Testing
- Magnetic Resonance Imaging scan sequences of the head, neck, and chest, Pacemaker System
- Where
- 36 sites in Australia, Austria and 17 more
- Volunteers
- 266 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Constipation
Ultrafast MRI Imaging to Exclude Constipation
In haematological malignancy and in immunocompromised patients, constipation is a common symptom caused by a number of factors during treatment.
- Trial name
- FIESTA (NCT02658201)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Type 1 Diabetes
11C-5-HTP PET in Clinical Islet Transplantation
In people with type I diabetes, the insulin producing cells in the pancreas have been destroyed. Presently one can only evaluate the function of the graft through laboratory tests, blood sugars and the insulin requirements.
- Trial name
- NCT02689479
- Testing
- Positron-Emission Tomography, 11C-5-HTP, Magnetic Resonance Imaging
- Where
- 2 sites in Sweden
- Volunteers
- 8 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diagnostic Imaging
Magnevist Post-marketing Surveillance in Japan
This study is a regulatory post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Magnevist at a dose of more than 0.2 ml/kg for MR angiography of peripheral…
- Trial name
- NCT01376739
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882)
- Where
- Japan
- Volunteers
- 2,051 people
- Sponsor
- Bayer