Clinical trials: Diagnostic Imaging Utilization
Smoking
Genetic Differences in Limbic Activation Associated With Nicotine Withdrawal
Objectives: To evaluate neural correlates associated with emotional processing during nicotine withdrawal preferentially involving the amygdala and associated areas within the corticolimbic and mesolimbic circuitry.
- Trial name
- NCT00664404
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Breast Neoplasms
Delphinus SoftVue Prospective Case Collection - ARM 2
The SoftVue™ is a whole breast ultrasound system with an automated scanning curvilinear ring-array transducer that employs UST. It is currently cleared under FDA 510(k) K123209 and K142517 for use as both a B-mode ultrasonic…
- Trial name
- SV PCC ARM2 (NCT02977247)
- Testing
- Non-Interventional, Automated Whole Breast Ultrasound
- Where
- 10 sites in United States
- Volunteers
- 1,150 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Mild Cognitive Impairment, Dementia
Implications for Management of PET Amyloid Classification Technology in the Imaging Dementia(IDEAS) Trial
The main purpose of this study is to build upon the evidence captured in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS; NCT02420756) trial to include valuable information regarding patient-reported outcomes and…
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer's Disease
- Trial name
- IMPACT2 (NCT02781220)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Utah
Mild Cognitive Impairment, Dementia
Implications for Management of PET Amyloid Classification Technology
The main purpose of this study is to explore the impact of an amyloid positron emission tomography and computed tomography (PET/CT) scan on physician diagnosis and management, including drug management and care practices, for…
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer's Disease
- Trial name
- IMPACT (NCT02778971)
- Testing
- [18F]Flutemetamol
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Utah
Leg Ulcer
Speckle Study: In Arterial, Mixed and Diabetic Foot Ulcers
This is a single centre open label study measuring microcirculatory flux using Speckle imaging Device. Microcirculation will be measured using laser speckle contrast imaging, at baseline and with the device active for 30 minutes…
- Trial name
- NCT03186560
- Testing
- gekoTM
- Where
- 3 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- Firstkind Ltd
Healthy Volunteers, Alcohol Drinking Related Problems
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Background: Problem drinking affects nearly half the people who drink alcohol. Drinking alcohol affects a person's social behavior and brain structure, but researchers don't have a good understanding of how.
- Conditions
- Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
- Trial name
- NCT03535129
- Testing
- Real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Mammogram Scheduled
Synthetic Aperture Radar Detection of Breast Tumours
The study will seek to understand the effective use of a novel Microwave Radar Breast Imaging System in a Symptomatic Breast Care Clinic.
- Trial name
- MARIA (NCT02493595)
- Where
- United Kingdom
- Volunteers
- 264 people
- Sponsor
- Micrima, Ltd.
Contrast Media, Liver, Biopsy, Fusion
Added Value in Combined Use of Fusion Imaging and Contrast-enhanced Ultrasonography
So far, there have been studies showing that the CEUS-grafted technique has added value in biopsy and RFA, but no studies have compared the group using only fusion and the group using CEUS+fusion.
- Trial name
- NCT04487288
- Testing
- SONAZOID
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Nicotine Dependence
Brain Reaction to Treatment of Nicotine Dependence
The purpose of the study was to determine how the treatments for cigarette craving work. Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before…
- Trial name
- NCT00108173
- Testing
- Zyban
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- US Department of Veterans Affairs
Nicotine Dependence
The Impact of Real-time Functional Magnetic Resonance Imaging (fMRI) Feedback on Response to Nicotine Cues
The purpose of this study is to develop a technique to provide feedback of brain activity and to use this technique to reduce levels of craving in nicotine dependent smokers.
- Trial name
- RTSmoking (NCT01411007)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sunscreen
Determination of Product Thickness Applied on Different Areas of the Face Using a Multispectral Imaging Method
The aim of the study is to determine: the thickness of the RV4369A truly applied on different areas of the face after single application of the product determined by a multispectral imaging method.
- Trial name
- NCT05837208
- Testing
- RV4369A cosmetic product
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Healthy
Use of Metabonomics and Body Imaging for Metabolic Health Assessment
The aim of this pilot study is to develop at Nestlé Research Center a database of metabolic profiles, body composition, food habits and physical activities on a large cohort of human volunteers.
- Trial name
- NCT02372968
- Testing
- Full body composition and of plasma and urine metabolites
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Procedural Anxiety, Procedural Pain
Stress Ball and Empathic Verbal-Tactile Interventions for Reducing Anxiety and Pain in Mammography and Breast Ultrasonography: A Randomized Trial
This prospective, randomized controlled trial aims to determine the effects of stress ball use and empathic verbal communication with therapeutic touch on anxiety and pain perception in women undergoing mammography and breast…
- Conditions
- Procedural Anxiety, Procedural Pain, Breast Imaging
- Trial name
- NCT07562828
- Testing
- Stress Ball, Empathic Verbal-Tactile Intervention
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Heterotopic Gastric Mucosa of the Proximal Esophagus
Influence of Routine Use of Narrow Band Imaging on Heterotopic Gastric Mucosa of the Proximal Esophagus Detection
The aim of the study is to determine whether Narrow Band Imaging(NBI) should be routinely used during esophagus inspection at diagnostic gastroscopy.
- Trial name
- NCT03015571
- Testing
- Esophagus inspection in Narrow Band imaging., Standard High definition endoscopy., Esophagus inspection in Narrow Band imaging and increased care.
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Tomasz Romańczyk
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Normal Physiology, Opioid Use Disorders
Brain Dopaminergic Signaling in Opioid Use Disorders
Background: The chemical messenger dopamine carries signals between brain cells. It may affect addiction. Heavy use of pain medicines called opioids may decrease the amount of dopamine available to the brain.
- Trial name
- NCT03190954
- Testing
- [11C]raclopride plus drug, [11C]NNC-112
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recurrent Renal Cell Cancer, Stage I Renal Cell Cancer
Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors
RATIONALE: Using fluorescence imaging may determine the extent of kidney tumors and help in planning surgery. PURPOSE: This phase I trial is studying the best way to give indocyanine green (ICG) fluorescence imaging in finding…
- Conditions
- Recurrent Renal Cell Cancer, Stage I Renal Cell Cancer, Stage II Renal Cell Cancer
- Trial name
- NCT01281488
- Testing
- fluorescence imaging, laparoscopic surgery, indocyanine green
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- City of Hope Medical Center
Premature Ventricular Contraction, Ventricular Tachycardia
Ventricular Arrhythmia Ablation With the Use of Non-Invasive ECG Imaging Technology
Researchers are trying to determine if the use of software called VIVO, made by Catheter Precision, Inc. can shorten the length of time it takes to perform an ablation procedure for either premature ventricular contractions…
- Trial name
- NCT04219501
- Testing
- VIVO
- Where
- United States
- Sponsor
- Mayo Clinic
Atrial Fibrillation
A Study to Assess the Use of The Sentinel Device During Atrial Fibrillation Ablation
Researchers are determining whether the use of the Sentinel cerebral protection device during atrial fibrillation ablation will affect the occurrence of new cerebral infarcts in brain MRI.
- Trial name
- NCT04683692
- Testing
- Magnetic Resonance Imaging (MRI), Laboratory Testing
- Where
- United States
- Sponsor
- Mayo Clinic
Lung Cancer
The Use of Breathing Synchronized PET/CT Imaging In the Detection and Quantification of FDG Uptake in Lung Nodules
The purpose of this study is to see if researchers can improve the detection of lung cancer by using a new method which will help us to take multiple snapshot images of the lungs while the patient is breathing.
- Trial name
- NCT00598065
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Memorial Sloan Kettering Cancer Center