Clinical trials: Diarrheal Diseases
Cholera, Diarrhea
Cholera-Hospital-Based-Intervention-for-7-days
The Cholera Hospital Based Intervention for 7 Days (CHoBI7) randomized controlled trial for transition to scale aimed to: (1) Develop and evaluate scalable approaches to integrate the CHoBI7 intervention into the services…
- Conditions
- Cholera, Diarrhea, Stunting
- Trial name
- CHoBI7 (NCT04008134)
- Testing
- CHoBI7 health facility program, CHoBI7 mHealth program, CHoBI7 home visit program
- Volunteers
- 2,626 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Diarrhea
Randomized Controlled Field Trial of a Probiotics to Assess Its Role in Preventig Diarrhoea
A therapeutic as well as preventive role of probiotics has been suggested from results of different studies using different probiotics that have been tested, usually lactic acid producing bacteria such as lactobacillus…
- Trial name
- Yakult (NCT00534170)
- Testing
- Probiotic (Yakult)
- Where
- India
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Indian Council of Medical Research
Diarrhoeal Disease, Hookworm Infection
Evaluating Impact of Improved Floors on Health
The goal of this intervention study is to learn about the impact of household flooring on health in rural Kenya, and test whether providing an improved (cement stabilised, washable) floor improves the health of children and their…
- Conditions
- Diarrhoeal Disease, Hookworm Infection, Ascaris Lumbricoides Infection, Trichuris Infection
- Trial name
- SABABU (NCT05914363)
- Testing
- Sealed washable floor plus behaviour change, Behaviour change intervention, Routine deworming
- Where
- Kenya
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Acute Diarrhea, Acute Respiratory Infection
Improving Nighttime Access to Care and Treatment (Part 2)
Children in resource-limited settings who develop illness at night are often isolated from pre-emergency care, resulting in progression to an emergency because families are forced to wait until morning to seek care.
- Conditions
- Acute Diarrhea, Acute Respiratory Infection, Acute Febrile Illness
- Trial name
- INACT2 (NCT03943654)
- Testing
- MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone
- Where
- Haiti
- Volunteers
- 391 people
- Sponsor
- University of Florida
Acute Respiratory Infection, Diarrheal Disease
Efficacy and Tolerance of a Follow-On Formula Fed to Children From 12-48 Months of Age in Salvador, Bahia, Brazil
The purpose is to determine if the consumption of study product has an effect on acute respiratory infections and/or diarrheal disease.
- Trial name
- NCT01431469
- Testing
- Cow's milk, Follow-On Formula
- Where
- Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Telemedicine, Pediatrics
Improving Nighttime Access to Care and Treatment; Part 4-Haiti
Children in resource-limited settings who develop illness at night are often isolated from care, resulting in progression to an emergency.
- Trial name
- INACT4-H (NCT05480930)
- Testing
- paper-based clinical decision support (dCDS) tool, digital clinical decision support (dCDS) tool
- Where
- Haiti
- Volunteers
- 7,124 people
- Sponsor
- University of Florida
Healthy, Diarrhea
Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children
This is a long term study on the efficacy of dietary calcium with or without probiotic strains in reducing the mean number of episodes and duration of diarrheal disease.
- Trial name
- NCT00512824
- Testing
- low calcium milk of 180 ml, regular milk of 180 ml, regular milk of 180 ml + probiotics
- Where
- Indonesia
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Intestinal Helminthiasis, Diarrhea
The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children
Cheap and effective drugs called 'anthelmintics' are routinely administered to children in developing countries to eliminate infections by parasitic helminths.
- Trial name
- NCT02597556
- Testing
- Albendazole
- Where
- Vietnam
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Diarrhea
Meatsafe Food Storage and Diarrhea Prevention Trial in Urban Bangladesh
The goal of this clinical trial was to evaluate whether a simple household food storage cabinet called a "meatsafe" could reduce bacterial contamination of complementary foods and decrease diarrhea among children aged 6 to 24…
- Trial name
- NCT07332078
- Testing
- Meatsafe Food Storage Cabinet
- Where
- Bangladesh
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Cholera, Diarrhea
Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo
The aim of the study is to evaluate the impact of a large-scale urban water supply improvement intervention on cholera and other diarrhoeal diseases.
- Trial name
- NCT02928341
- Testing
- Improved water supply
- Where
- Democratic Republic of the Congo
- Volunteers
- 4,556 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Dietary Rice Bran Supplementation
Pilot Feasibility of Rice Bran Supplementation in Nicaraguan Children
The purpose is to assess feasibility of rice bran consumption in weaning children and collect pilot data on gut microbiome and metabolome modulation with rice bran intake for diarrheal prevention.
- Trial name
- NCT02615886
- Testing
- Observational Control, Rice bran
- Where
- 2 sites in United States, Nicaragua
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Acute Diarrheal Disease, Acute Respiratory Infection
"Alcohol Based Hand Sanitizers for the Prevention of Acute Diarrheal Disease and Acute Respiratory Infection in Children Under 5 Attending Childcare Centers in Bogotá, Cundinamarca and Tolima, in Colombia: a Cluster Randomized Control Trial"
The purpose of this study is to conduct a Randomized Control Trial (RCT) in a developing country setting in order to evaluate the role of alcohol based hand sanitizers (ABHS) in preventing the transmission of infectious diseases…
- Trial name
- NCT00963391
- Testing
- ABHS use
- Where
- Colombia
- Volunteers
- 1,727 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Diarrhoea
Double-blinded Trial of Household-based Chlorination in India
The proposed study is a 12-month double-blinded, randomized, placebo-controlled trial to determine if the impact of treating water with chlorine at the household level is effective in preventing diarrhea among young children.
- Trial name
- NCT01202383
- Testing
- Household-based water treatment with NADCC tablets
- Where
- India
- Volunteers
- 2,163 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Diarrhea
Evaluation of a mHealth Platform for Diarrheal Disease Decision-support
The study hypothesis is that clinical decision-support on a smartphone for the management of diarrheal disease will improve the assessment of dehydration, reduce IV fluid usage, and increase guideline adherence for the use of…
- Trial name
- NCT03154229
- Testing
- Smartphone-based decision-support, Paper-based decision-support, Pre-Assessment of practices
- Where
- Bangladesh
- Volunteers
- 4,975 people
- Sponsor
- University of Florida
Cryptosporidium; Diarrhea, Cryptosporidiosis
Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya.
- Conditions
- Cryptosporidium; Diarrhea, Cryptosporidiosis, Communicable Diseases, Diarrheal Disease
- Trial name
- NCT01695304
- Testing
- Ceramic water filter
- Where
- Kenya
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Acute Respiratory Infection, Diarrheal Disease
Efficacy and Tolerance of a Follow-On Formula Fed to Children From 36-48 Months of Age
The purpose is to determine if the consumption of study product has an effect on acute respiratory infections and/or diarrheal disease.
- Trial name
- NCT01488435
- Testing
- Cow's milk, Follow-On Formula
- Where
- China
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Gastroenteritis
Impact of Emergency Department Probiotic Treatment of Diarrheal Illness on Daycare Attendance
The objective of this study is to determine for previously healthy children, who present to an ED with acute gastroenteritis, if the probability of daycare absenteeism is significantly different in those who receive a probiotic…
- Trial name
- NCT00760773
- Testing
- Lacidophil (experimental high dose), Lacidophil (experimental standard dose)
- Where
- 3 sites in Canada
- Volunteers
- 132 people
- Sponsor
- The Hospital for Sick Children
Compliant Behavior, Diarrheal Disease
Rural China Electric Kettle Promotion Program
This study will evaluate the impact of a pilot Rural Electric Kettle Promotion Program offered to low-income households in rural Anhui Province, China.
- Conditions
- Compliant Behavior, Diarrheal Disease, Pollution; Exposure
- Trial name
- NCT03376152
- Testing
- Electric Kettle Promotion
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Diarrhea
Impact of Hand Washing and WASH Educational Intervention on Under-five Diarrheal Diseases
The investigators evaluated the impact of water, sanitation and hygiene educational Intervention and hand washing with soap on the incidence of diarrhea among under-five children.
- Trial name
- WASH (NCT02779010)
- Testing
- Hand washing with soap and Health education
- Volunteers
- 1,190 people, healthy volunteers welcome
- Sponsor
- Ethiopian Institute of Water Resources