Clinical trials: Disabilities
Pathology
Different Clinicopathological Features of Non-Elderly Sigmoid Volvulus Patients
Sigmoid volvulus is frequently seen in male patients over 60 years old. In the sigmoid volvulus <60 age groups, the male/female ratio is close to each other.
- Trial name
- NCT04360525
- Testing
- Reasons
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Preterm Birth
The Australian Placental Transfusion Study (APTS): Should Very Pre Term Babies Receive a Placental Blood Transfusion at Birth Via Deferring Cord Clamping Versus Standard Cord Clamping Procedures?
To establish if placental transfusion, using deferred cord clamping for 60 seconds or more while holding the baby at or below the level of the placenta, will improve survival without disability compared with standard early cord…
- Trial name
- APTS (NCT02606058)
- Testing
- Deferred cord clamping
- Where
- 26 sites in United States, Australia and 5 more
- Volunteers
- 1,637 people
- Sponsor
- University of Sydney
Down Syndrome
Digital Dysmorphology Project
In this study, the investigators propose a novel method to detect Down syndrome using photography for facial dysmorphology, a tool called computer-aided diagnosis (CAD).
- Trial name
- NCT02651493
- Testing
- photographs
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Kevin Cleary
Prader-Willi Syndrome
Cannabidiol Oral Solution for the Treatment of Patients With Prader-Willi Syndrome
The primary objective of this study is to assess the efficacy of cannabidiol oral solution on hyperphagia-related behavior in patients with Prader-Willi Syndrome (PWS).
- Trial name
- NCT02844933
- Testing
- Cannabidiol
- Where
- 7 sites in United States
- Volunteers
- 7 people
- Sponsor
- Radius Pharmaceuticals, Inc.
Migraine
Effects Of Dry Needling On Sternocleidomastoid Muscle For Pain And Disability In Migraine
To determine the effects, sequel of dry needling in migraine by resolving MTrPs in sternocleidomastoid muscle. To determine the possession of dry needling technique to mitigate the frequency, intensity and duration of headache.
- Trial name
- NCT05285852
- Testing
- Dry Needling
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
RETT Syndrome With Proven MECP2 Mutation, Rett Syndrome
Efficacy and Safety of NTI164 in Children and Young Adults With Rett Syndrome
The FENRTT2 study will investigate the efficacy and safety of a medicinal cannabis plant extract with extremely low THC (delta-9-tetrahydrocannabinol), NTI164, on Rett syndrome (RTT) in a crossover design.
- Trial name
- TRANSCEND (NCT07257978)
- Testing
- NTI164
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Fenix Innovation Group
Attention Disturbances
Attention and Achievement: A Mind Wandering Investigation
This study assesses the impact of mind-wandering on reading and math.
- Trial name
- NCT05296252
- Testing
- mind-wandering intervention, mind-wandering comparison
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Houston
Down Syndrome
Neurodevelopmental Treatment for Balance and Mobility in Children With Down Syndrome
The goal of this clinical trial is to evaluate whether Neurodevelopmental Treatment (NDT) can improve balance, mobility, walking capacity, and functional independence in preschool children with Down syndrome.
- Trial name
- NCT07653399
- Testing
- Neurodevelopmental Treatment (NDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Nisantasi University
Behavior Problem, Developmental Delay
Stamford Group Family Nurture Intervention
The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children.
- Conditions
- Behavior Problem, Developmental Delay, Emotional Disturbances, Family Conflict
- Trial name
- NCT03442439
- Testing
- Nutrition and Play Intervention, Family Nurture Intervention
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
Rett Syndrome
Study of the Pathogenesis of Rett Syndrome
OBJECTIVES: I. Extend current knowledge of the phenotype and natural history of Rett syndrome (RS). II. Continue the search for a cytogenetic and/or DNA marker. III.
- Trial name
- NCT00004807
- Testing
- dextromethorphan, topiramate, Donepezil
- Volunteers
- 120 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dyslexia
Reading Problems in Children Living in Urban Areas
The first line of defense against reading disabilities is good classroom reading instruction. This study describes how characteristics of students, teachers, and instruction relate to academic achievement in inner-city…
- Trial name
- NCT00065832
- Testing
- Reading Instruction
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pediatric ALL, Infant Development
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes.
- Conditions
- Pediatric ALL, Infant Development, Neurodevelopmental Disorders
- Trial name
- NCT04321200
- Testing
- PANDA Gym, Mobile App
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Learning Disability
Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities
Research and intervention programs for students with learning disabilities (LD) typically address child and family characteristics without examining the school context and conditions that affect adjustment.
- Trial name
- NCT00246792
- Testing
- Group treatment
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Toronto
Obstructive Sleep Apnea
Optimizing the Management of OSA in Children With Down Syndrome
The objective of this retrospective descriptive study is to assess current practices for the screening and surgical treatment of OSA in children with Down syndrome at the Strasbourg University Hospital and to disseminate a…
- Trial name
- SAOS-21 (NCT07334444)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Fragile X Syndrome
Biomarker and DNA Collection in Subjects Participating in Protocol 22003
The subjects that meet the inclusion and exclusion criteria and consent to participate in protocol 22003 will be offered participation in 22003A which will evaluate secreted protein before and after treatment with STX209 and…
- Trial name
- NCT00892580
- Testing
- STX209
- Where
- 8 sites in United States
- Volunteers
- 32 people
- Sponsor
- Seaside Therapeutics, Inc.
Child Behavior Problem, Intellectual Disability
Determining the Effectiveness of Sexual Health and Development Education for Children With Intellectual Disability
By integrating sexuality and disability literatures, theories, and research, this study aims to: determine the effectiveness of sexual health and development education for children (12-18 years) with mild to moderate intellectual…
- Conditions
- Child Behavior Problem, Intellectual Disability, Sexuality
- Trial name
- NCT04635969
- Testing
- Sexual Health and Development Education for Children With Intellectual Disability
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aylin KURT
Disability Physical
Human Factor Validation of Pediatric Mobility Device
The purpose of this study is to validate the user interface of a pediatric power mobility device by establishing that the product is safe and effective use for the intended users.
- Trial name
- NCT03714256
- Testing
- Device, patient mobility, powered
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Permobil, Inc.
Children, Adult
Pilates Exercises on Pain, Functional Disability and ROM Among Children With Text Neck Syndrome
Text Neck' is a term used to describe a posture that is caused by leaning forward for long period of time such as reading or texting on smartphone.
- Trial name
- NCT06893705
- Testing
- Conventional Therapy, Pilates+Conventional Therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Myotonic Dystrophy 1, Huntington Disease
NIPD on cffDNA for Triplet Repeat Diseases
The purprose of this study is to develop and validate an analytical NIPD test for triplet repeat disesases by NGS analysis from maternal blood, searching for the familial mutation in families at risk of having one of the…
- Conditions
- Myotonic Dystrophy 1, Huntington Disease, Fragile X Syndrome
- Trial name
- NCT04698551
- Testing
- Non invasive prenatal diagnosis
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Montpellier
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