Clinical trials: Disabilities
Parkinson Disease, Physical Inactivity
Integrating AI in Postural Rehabilitation for Parkinson's Disease
Postural abnormalities are highly disabling complications of Parkinson's disease (PD). These include camptocormia, anterocollis, and Pisa Syndrome (PS).
- Conditions
- Parkinson Disease, Physical Inactivity, Physical Disability, Pisa Syndrome
- Trial name
- NCT07010328
- Testing
- Neurorehabilitation, AI-based home rehabilitation for postural disorders
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Genetic Disorder, Prader-Willi Syndrome
Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers
This trial is conducted in United States of America (USA). The aim of this trial is to examine the bioequivalence of Norditropin® versus Genotropin® in healthy adult volunteers.
- Conditions
- Genetic Disorder, Prader-Willi Syndrome, Growth Disorder, Idiopathic Short Stature
- Trial name
- NCT01401244
- Testing
- somatropin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Novo Nordisk A/S
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Elderly, Sarcopenia
Early Detection of Disability and Health Promotion for Community-dwelling Elderly
This study evaluates the effects of exercise intervention on muscle strength and walking speed for the community-dwelling elderly.
- Trial name
- NCT03607136
- Testing
- exercise training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Vascular Disease, Peripheral, Amputation
Vascular Amputee Physical Performance Qualitative (VAmPP-Q) Study
Background: Peripheral arterial disease (PAD) is the main cause of amputation to the lower limb within the UK, affecting over 20% of adults older than 70 years.
- Conditions
- Vascular Disease, Peripheral, Amputation, Physical Disability
- Trial name
- VAmPP-Q (NCT05860764)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Leicester
Rett Syndrome, RTT
Efficacy and Safety of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome
To evaluate the efficacy of cannabidiol oral solution (GWP42003-P, CBD-OS) in reducing symptom severity when compared with placebo, in participants with Rett syndrome.
- Trial name
- ARCH (NCT03848832)
- Testing
- GWP42003-P
- Where
- 26 sites in United States, Italy and 2 more
- Volunteers
- 29 people
- Sponsor
- Jazz Pharmaceuticals
PTSD, Trauma, Psychological
Narrative Exposure Therapy for Adults With Intellectual Disability
The purpose of the study is to identify how Narrative Exposure Therapy (NET) can be adapted for delivery with adults with mild Intellectual Disability (ID) and to explore whether NET can reduce symptoms of traumatic stress in…
- Trial name
- NCT04418752
- Testing
- Psychological therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nottingham
Disability Evaluation, Recovery of Function
Effectiveness of VR Rehabilitation for People With Asymmetrical Gait Patterns
A randomized comparative study will be conducted to evaluate the rehabilitation process using a VR-based application versus conventional therapy in 40 patients (sample size determined using a sample size calculator).
- Conditions
- Disability Evaluation, Recovery of Function, Rehabilitation
- Trial name
- NCT07568821
- Testing
- Virtual Reality (VR) and Standard Rehabilitation, Standard Rehabilitation
- Volunteers
- 40 people
- Sponsor
- University of Rzeszow
Dyslexia, Dyslexia, Developmental
Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words
The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth.
- Conditions
- Dyslexia, Dyslexia, Developmental, Learning; Developmental Disorder, Reading
- Trial name
- NCT06387615
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Down Syndrome, Trisomy 21
Down Syndrome Metabolic Health Study
The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS).
- Trial name
- NCT01821300
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Fragile X Syndrome, Healthy Volunteers
Protein Synthesis in the Brain of Patients With Fragile X Syndrome
Biosynthesis of proteins is essential for growth and continued maintenance of the entire neuron including axons, dendrites, and synaptic terminals, and it is clearly one of the important biochemical processes underlying adaptive…
- Trial name
- NCT00362843
- Testing
- [15-O]water
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- National Institute of Mental Health (NIMH)
Rotator Cuff Tendinopathy
Kinetic Chain Approach for Rotator Cuff Tendinopathy
The aim of this research is to determine the effectiveness of the kinetic chain approach on pain, functional disability and kinesiophobia in patient with rotator cuff tendinopathy.
- Trial name
- NCT06838767
- Testing
- Conventional treatment, Kinetic chain approach
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Developmental Delay
18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study
The purpose of this study is to examine differences in the long-term effects of immediate versus delayed cord clamping at birth on developmental outcomes of our study infants at 18-22 months corrected age.
- Trial name
- 18mo (NCT01426698)
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Rhode Island
Developmental Disabilities, Autistic Spectrum Disorder
"Family-centered" Pediatric Rehabilitation Services in Children With Developmental Disabilities
Developmental disability is a severe chronic disabled condition caused by mental or physical impairments. Children with developmental disabilities may face life-long difficulties in motor functioning, self-care, condition…
- Trial name
- NCT02057809
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Chang Gung University
Frailty, Disability Physical
Functional Decline and QoL in People Aging with HIV in Asia
This is a multi-center prospective cross-sectional study to determine the burden of decline in intrinsic capacity and functional ability, and the prevalence of geriatric syndromes, such as frailty, and disability in adult people…
- Conditions
- Frailty, Disability Physical, HIV/AIDS
- Trial name
- NCT04212884
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Neck Pain, Neck Disability
Scapular Depression at Rest: Implications for Cervical Pain and Functional Outcomes
The purpose of this study is to explore whether depressed scapular alignment is associated with increased neck pain and decreased cervical functional capacity, and to investigate the correlation between the mean vertical scapular…
- Trial name
- NCT07484984
- Testing
- Assessment of the Vertical Scapular Position at Rest, Measurement of the Mean Vertical Scapular Distance at Rest, The Arabic version of Bournemouth questionnaire for neck pain (BQN)
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Cairo University
Developmental Disability, Food Assistance
Integrating WIC With Early Childhood Systems of Developmental Care
This study's goals are to improve connections between Oregon Women, Infants, \& Children (WIC) clinics, primary care providers, and Early Intervention/Early Childhood Special Education programs (EI/ECSE), in order to help…
- Conditions
- Developmental Disability, Food Assistance, Health Care Disparity
- Trial name
- CDC-WIC (NCT04159038)
- Testing
- Intervention Group, Control group
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Oregon Health and Science University
Weight Loss, Food Habits
School Intervention With Daily Physical Activity and Healthy Food for Students With an Intellectual Disability.
A whole of school intervention with daily physical activity and healthy food for students with intellectual disabilities. The aim is to provide plenty of concrete examples of healthy life style choices and using school personnel…
- Conditions
- Weight Loss, Food Habits, Mental Retardation
- Trial name
- NCT01291238
- Testing
- Healthier, Smarter, Happier
- Where
- Sweden
- Volunteers
- 145 people
- Sponsor
- Karolinska Institutet
Spondylolisthesis, Degenerative, Spondylolisthesis, Isthmic
Spinal Fusion and Rehabilitation Study
The aim of the present study is to analyse the significance of postoperative combined strength and aerobic training for outcome of the lumbar fusion patients compared to usual care (patients with isthmic or degenerative…
- Trial name
- NCT00834015
- Testing
- Outcome of lumbar spinal fusion patients and significance of postoperative exercise therapy: A randomized controlled trial
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Jyväskylä Central Hospital
Prader Willi Syndrome, Hypoglycemia
Hypoglycemia in Prader-Willi Syndrome
This project will study whether infants with Prader-Willi Syndrome experience low blood sugars after short periods of fasting. This study will also evaluate metabolic markers in the blood to determine if infants with Prader-Willi…
- Trial name
- NCT01897363
- Testing
- Infants with Prader-Willi Syndrome
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
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