Clinical trials: Disinfection
Dysentery, Diarrhoea
Solar Disinfection (SODIS) of Drinking Water for Use in Developing Countries or in Emergency Situations
SODISWATER was a health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water.
- Trial name
- SODISWATER (NCT01306383)
- Testing
- SODIS Bottle
- Where
- 3 sites in Cambodia, Kenya and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Water-Related Diseases
SAFEWATER Health & Behaviour Impact Field Trials; Colombia
At least 1.8 billion people globally use a source of drinking water that is faecally contaminated and thus likely to lead to diarrheal illness: nearly 1,000 children die each day due to water and sanitation-related diarrhoeal…
- Trial name
- SAFEWATER (NCT04829981)
- Testing
- SAFEWATER systems for drinking water disinfection, Behaviour change interventions
- Where
- 3 sites in Colombia, Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Hand Eczema, Hand Dermatitis
Consequences of Intensified Handwash and Hand Disinfection Among Children During the COVID19 Pandemic
During the COVID-19 pandemic after reopening of the country, school, kindergarten and daycare, children have been obligated to do frequent handwash.
- Conditions
- Hand Eczema, Hand Dermatitis, Covid19
- Trial name
- NCT04375410
- Where
- Denmark
- Volunteers
- 6,273 people
- Sponsor
- Regionshospital Nordjylland
Pain, Postoperative
Evaluation of Postoperative Pain With Eddy Tips (EPPET)
This investigation will focus on the use of EDDY tips, because it is known that the complete debridement of the canal is very difficult, which leads to an accumulation of tissue debris, bacteria and their products, resulting in…
- Trial name
- NCT03946306
- Testing
- 5,25% NaOCl with syringe needle irrigation alone, EDDY
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- Universidade do Porto
Hygiene
Reducing Visitors- and Personnel-associated Infection Risk on Perinatal Care Station
The rate of infectious diseases (amnioninfection syndrome (AIS), fetal inflammatory response syndrome (FIRS), early-onset neonatal sepsis (EONS)) in perinatal care / neonatology is steadily rising in Germany.
- Trial name
- NCT03032887
- Testing
- voice prompts, agitation
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Diarrhea, Gastrointestinal Infection
Wells and Enteric Disease Transmission
Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from…
- Conditions
- Diarrhea, Gastrointestinal Infection, Respiratory Viral Infection, Waterborne Diseases
- Trial name
- WET (NCT04826991)
- Testing
- Active UV Device, Inactive UV Device
- Where
- United States
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Temple University
Hand, Hygiene Practices and Knowledge
Effectiveness of VR on the Sustainability of Hand Hygiene Compliance: School-based RCT With 10-month Follow-up
This study aims to evaluate the effectiveness of a VR intervention on teaching handwashing skills which are promoted by the Centre for Health Protection, Department of Health, HKSAR.
- Trial name
- HKU-VR-2026 (NCT07659340)
- Testing
- VR Handwashing Game (2 sessions), VR Handwashing Game (1 session) + Video on hand hygiene (1 session)
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Respiratory Infections, Gastrointestinal Diseases
A Randomized Controlled Trial of a School Disinfection and Hand Hygiene Program
The objective of the trial is to assess the impact of a disinfection and hand hygiene program on absenteeism in elementary school classrooms.
- Trial name
- NCT00514670
- Testing
- Alcohol-based hand sanitizer & quaternary ammonium wipes
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- Boston Children's Hospital
Infected Immature Permanent Teeth
Regenerative Endodontic Therapy (RET) for the Management of Immature Non-vital Permanent Teeth in Children
This study evaluates the efficacy of Antibiotic pastes or Calcium hydroxide disinfection on healing of periapical pathology and continued root development of infected non-vital immature permanent teeth in children.
- Trial name
- NCT03327844
- Testing
- RET using antibiotics (Ciprofloxacin and Metronidazole), RET using non-setting Calcium Hydroxide
- Where
- 2 sites in Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Diarrhea, E.Coli Infections
Trial of Low-cost Microbiological Water Test Kits
The present study is a cluster randomized control trial of low-cost microbiological water test kits in rural and peri-urban communities in the Kanpur region of Uttar Pradesh, India.
- Trial name
- NCT03021434
- Testing
- Community and household water safety education sessions, Household-specific water quality information, Low-cost microbiological water test kits
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Urinary Tract Infections
Chlorhexidine to Prevent Catheter-related Urinary Tract Infection
The study is to investigate whether chlorhexidine (CHG)-based antiseptics is more effective to prevent catheter-related urinary tract infection (CAUTI) among inhospital patients who required Foley catheter insertion.
- Trial name
- NCT05712434
- Testing
- Long Intervention, Mid-length Intervention, Short Intervention
- Where
- Taiwan
- Volunteers
- 30,994 people
- Sponsor
- National Taiwan University Hospital
Apical Periodontitis
Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment
Post-treatment apical periodontitis is commonly associated with persistent intracanal infection following root canal treatment. Effective disinfection of the complex root canal system during nonsurgical retreatment remains…
- Trial name
- NCT07469150
- Testing
- GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Root Canal Disinfection
Estimate the Effect of aPDT on Root Canal Disinfection
The aim of this study is to compare the clinical effect of traditional root canal disinfection and aPDT on root canal disinfection. And provide the reference for clinical application and experience.
- Trial name
- NCT02929927
- Testing
- Rubber dam isolation, aPDT, 1% iodine tincture
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Nosocomial Infection
Biosafety of Musical Instruments in the ICU
This study investigates the efficacy of the institutional disinfection protocol for musical instruments in the ICU of the music therapy service of the University Hospital Fundación Santa Fe de Bogotá (FSFB), Colombia.
- Trial name
- NCT05988853
- Testing
- follow-up of patients
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Santa Fe de Bogota
Periprosthetic Joint Infections
Laser Disinfection in Periprosthetic Joint Infection
The eradication of biofilms from infected implants is still an unsolved challenge. The high-energy light beam of an Er:YAG laser causes rapid heating and explosive ablation of tissue.
- Trial name
- NCT06440564
- Testing
- Er:YAG Laser irradiation
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Problems With Dentures
Evaluation of Sodium Hypochlorite as a Denture Cleanser
The present study tried to integrate all aspects of denture care: patient satisfaction with the treatment, denture decontamination and base material defects after decontamination processing.
- Trial name
- NCT01616355
- Testing
- Sodium hypochlorite immersion
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Infection
Interactions of Environmental and Human Microbial Communities in a Pediatric Oncology Hospital
Microorganisms that colonize hospital environments play an important role in the transmission of hospital acquired infections (HAI) and multi-drug resistant organisms.
- Trial name
- NCT02948335
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- St. Jude Children's Research Hospital
COVID-19 Respiratory Infection, Respiratory Virus Infection
Preventing Respiratory Viral Illness Invisibly
Elderly people who have multiple health problems are at higher risk of illness from viral respiratory infections, such as influenza (the flu) and COVID-19.
- Conditions
- COVID-19 Respiratory Infection, Respiratory Virus Infection, Influenza -Like Illness
- Trial name
- PRiVII (NCT05084898)
- Testing
- Far-UVC light as an additional method of disinfection
- Where
- 3 sites in Canada
- Volunteers
- 550 people
- Sponsor
- Kenneth Rockwood
Dimensional Changes
Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study
This quasi-experimental comparative study investigates the effects of incorporating various self-disinfecting agents-0.2% Chlorhexidine (CHX), 1% Chitosan solution, 0.2% Silver Nitrate (AgNO3), green-synthesized Silver…
- Trial name
- NCT06899672
- Testing
- Alginate mixed with distilled water, 0.2% Chlorhexidine + Alginate, 1% Chitosan + Alginate
- Volunteers
- 96 people
- Sponsor
- Altamash Institute of Dental Medicine
Diarrhea, Communicable Diseases
Automatic Chlorination and Child Health in Urban Bangladesh
Municipal water networks within industrialized countries typically rely on centralized treatment to manage piped water quality. Optimal water quality at the tap, however, requires well-maintained piped distribution networks, and…
- Trial name
- NCT02606981
- Testing
- Water chlorination by the Flogenic, Active control, vitamin C dosing into water
- Where
- Bangladesh
- Volunteers
- 1,549 people, healthy volunteers welcome
- Sponsor
- Stanford University