Clinical trials: Disorder of Aging
Fat Mass, Risk Factors Cardiovascular Disease
Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging
A large ongoing randomized, open-label trial aimed at evaluating the effects of two different dietary interventions, FMD and LD, on body composition and cardiovascular (CV) biomarkers in a real word population (NCT05698654) is…
- Conditions
- Fat Mass, Risk Factors Cardiovascular Disease, Epigenetic Aging, Metabolism Changes
- Trial name
- NCT07255300
- Testing
- fasting mimicking diet
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Aging
Large-scale Multi-omics Analysis of Cerebrospinal Fluid
The aim of this study is to explore the role of cerebrospinal fluid (CSF) biomarkers in aging and neurodegenerative diseases.
- Trial name
- NCT06636201
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Maternal-Fetal Relations, Muscle Weakness
Developmental ORIgins of Healthy and Unhealthy AgeiNg: the Role of Maternal Obesity
The prevalence of obesity in the developed world has increased markedly over the last 20 years. Considering the prevalence of obese and overweight adult subjects, and the fact that pregnancy itself induces a state of insulin…
- Conditions
- Maternal-Fetal Relations, Muscle Weakness, Insulin Resistance
- Trial name
- DORIAN (NCT01931540)
- Testing
- Exercise Training
- Where
- 2 sites in Finland
- Volunteers
- 48 people
- Sponsor
- Turku University Hospital
Dementia With Lewy Bodies
The PACE-DLB Study
The PACE-DLB Study is for people with at least moderate dementia with Lewy bodies (DLB) and their primary caregiver. The study's goals are to learn more about the experiences of people with DLB and their caregivers as DLB…
- Trial name
- NCT04829656
- Where
- 5 sites in United States
- Volunteers
- 378 people
- Sponsor
- University of Florida
Sarcopenia, Muscle Loss
Comparison of Computed Tomography Data With Routine Measurements Concerning Bone and Muscle Health of Aged Individuals
This study focuses on researching sarcopenia and bone loss (osteoporosis), aiming to develop early and effective methods for diagnosis and treatment.
- Conditions
- Sarcopenia, Muscle Loss, Osteoporosis
- Trial name
- SARCATAR (NCT06488872)
- Testing
- comparison of CT scan with routinely assessed methods of muscle mass and strength
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Thrombosis
Ultrasound Elasticity Imaging of Venous Thrombi
The purpose of this study is to see if the investigators can use ultrasound imaging to determine the type of clots in patients to help better manage their care.
- Trial name
- NCT00726947
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- University of Michigan
Atherosclerosis, Life Style
Effect of a Cardiovascular Health Promotion Program in Youth - The Tyrolean Early Vascular Ageing-study
Atherosclerosis - the main cause of cardiovascular diseases - starts already in childhood. The Tyrolean Early Vascular Ageing-study aims to improve the vascular health of Tyrolean adolescents by a multi-layer intervention program.
- Trial name
- EVA-Tyrol (NCT03929692)
- Testing
- Multi-layer health promotion program, Standard health education
- Where
- 2 sites in Austria, Italy
- Volunteers
- 2,102 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Glaucoma
Glaucoma Within Northern Ireland Cohort for the Longitudinal Study of Ageing
Glaucoma is the leading cause of irreversible blindness worldwide. It is caused by damage to the optic nerve between the back of the eye and the brain leading to progressive blindness.
- Trial name
- GwNICOLA (NCT03109665)
- Testing
- SD-OCT Angiography, SD-OCT
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Queen's University, Belfast
Alzheimer's Disease
Development and Decline of Brain and Cognition Through the Life Span
The protocol objectives are to enable prospective IRB review of research using human MRI scans and data collected under other branch protocols or extramural sources.
- Trial name
- NCT00880451
- Where
- United States
- Sponsor
- National Institute of Mental Health (NIMH)