Clinical trials: Disruptive Behavior
Attention-deficit/Hyperactivity Disorder, Oppositional Defiant Disorder in Children
A Study to Assess the Effectiveness and Safety of Clonidine Extended-Release OnydaTM XR in Children With ADHD and ODD
This is a study to see how safe and effective OnydaTM XR is to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 years who also have Oppositional Defiant Disorder (ODD).
- Trial name
- NCT07044609
- Testing
- Clonidine extended release oral suspension
- Volunteers
- 162 people
- Sponsor
- Las Vegas Medical Research, LLC DBA Vector Clinical Trials
Attention Deficit Hyperactivity Disorder
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
This Phase 3 pivotal efficacy trial will examine the effects of HLD200 (methylphenidate) in patients aged 6-12 years with ADHD in a laboratory classroom setting.
- Trial name
- NCT02493777
- Testing
- HLD200 methylphenidate hydrochloride (MPH) Capsules
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
ADHD
Safety and Efficacy of ADDERALL XR in the Treatment of Adolescents Aged 13-17 With Attention Deficit Hyperactivity Disorder (ADHD)
Assess the safety and efficacy of ADDERALL XR compared to placebo in the treatment of adolescents (aged 13-17) with ADHD. Subjects were assigned to one of two cohorts based on weight (<= 75 kg or > 75 kg).
- Trial name
- NCT00507065
- Testing
- Mixed salts of a single-entity amphetamine (ADDERALL XR)
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- Shire
Handwriting, Telerehabilitation
Effect of Telerehabilitation on Handwriting Performance in Children With ADHD: RCT
This is a randomized controlled study examining the effect of telerehabilitation on fine motor performance and handwriting difficulties experienced by children with attention deficit hyperactivity disorder.
- Conditions
- Handwriting, Telerehabilitation, Fine Motor Skills
- Trial name
- NCT04697771
- Testing
- Fine Motor Skills Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
ADHD
Analog Classroom Study Comparison of ADDERALL XR With STRATTERA in Children Aged 6-12 With ADHD
Evaluate the behavioral effects of ADDERALL XR versus STRATTERA under controlled conditions utilizing the SKAMP deportment scale.
- Trial name
- NCT00506727
- Testing
- Mixed amphetamine salts (ADDERALL XR), Atomoxetine hydrochloride
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Shire
Attention-Deficit/Hyperactivity Disorder (ADHD)
Virtual Reality for Parent Training Intervention
Previous research has shown how parental responses can affect ADHD symptoms by triggering dysfunctional cyclic processes. Therefore, it may be useful within rehabilitative treatments to include parent training (PT).
- Trial name
- NCT05809388
- Testing
- Parent training, Virtual Reality-assisted PT sessions
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder
Virtual Reality-assisted Cognitive Rehabilitation in Autistic Youth With ADHD
This study aims to evaluate the effectiveness of a virtual reality-based intervention using the Virtual Reality Rehabilitation System (VRRS) to improve executive functions in autistic and ADHD youth aged 8 to 18 years.
- Trial name
- NCT07426302
- Testing
- VRRS Cognitive Training, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Irritability, Disruptive Mood Dysregulation Disorder
Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy
Background: Irritability is defined as proneness to anger that may impair a person's ability to function. It is a common reason for why some children need mental health care.
- Conditions
- Irritability, Disruptive Mood Dysregulation Disorder, Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT07640802
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Attention Deficit Hyperactivity Disorder, Substance Use Disorder
Efficacy of Atomoxetine for ADHD in Adolescents and Young Adults With SUD
The primary objective of the study is to investigate the efficacy of Atomoxetine (ATMX) in the treatments of adolescent and young adult Attention Deficit Hyperactivity Disorder (ADHD) with comorbid Substance Use Disorder (SUD).
- Trial name
- NCT01207622
- Testing
- Atomoxetine
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)
Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home…
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- FAST (NCT06133231)
- Testing
- Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Attention Deficit Hyperactivity Disorder (ADHD)
Crossover Study to Evaluate the Efficacy of AR11 in Pediatric Patients With ADHD in a Laboratory Classroom Setting
This is a dose-optimized, randomized, double-blind, placebo-controlled crossover study in approximately 100 pediatric patients (aged 6 to 12 years) with ADHD.
- Trial name
- NCT01986062
- Testing
- AR11
- Where
- 7 sites in United States
- Volunteers
- 97 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Oppositional Defiant Disorder in Children, Oppositional Defiant Disorder
Yoga Therapy and Oppositional Defiant Disorder Behaviors
This clinical trial aims to learn about, test, and compare the effect yoga therapy has on improving disruptive behaviors (e.g., oppositional defiant disorder) in Latino preschool children and parent-child interactions.
- Trial name
- YTODD (NCT05865067)
- Testing
- Yoga Therapy, Exercise
- Where
- Puerto Rico
- Volunteers
- 34 people
- Sponsor
- University of Puerto Rico
ADHD
A Study to Evaluate the Efficacy, Safety and Tolerability of Oral AK0901 in Children With ADHD
This study is a Phase 3, multicenter, dose-optimized, double-blind, randomized, placebo-controlled study designed to evaluate the efficacy, safety, and tolerability of oral AK0901 capsules in children 6 to 12 years old with…
- Trial name
- NCT06359899
- Testing
- AK0901 capsule
- Where
- 2 sites in China
- Volunteers
- 55 people
- Sponsor
- Shanghai Ark Biopharmaceutical Co., Ltd.
Attention Deficit Hyperactivity Disorder
Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD
Approximately 1-in-20 children worldwide have Attention Deficit Hyperactivity Disorder (ADHD), a condition associated with disabling inattention, hyperactivity and impulsivity.
- Trial name
- NCT05600881
- Testing
- Methylphenidate
- Volunteers
- 35 people
- Sponsor
- University of Dublin, Trinity College
Attention Deficit Hyperactivity Disorder
Atomoxetine for Children With Acquired Attentional Disorders Following Completion of Chemotherapy for ALL
This study is a double-blind, placebo-controlled, parallel group trial of atomoxetine (1.8 mg/kg) for the management of chemotherapy-related acquired attentional disorders in children who have survived Acute Lymphocytic Leukemia.
- Trial name
- NCT00299234
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Monarch Medical Research
Attention Deficit Hyperactivity Disorder
Lab School Day Study for CONCERTA of Older Children With ADHD
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with attention deficit hyperactivity disorder…
- Trial name
- NCT00799409
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Attention Deficit Hyperactivity Disorder
Examining Benefits of Modified Cogmed Training With ADHD at Cambridge Memorial Hospital(CMH)
ADHD youth (8-16 years) will be randomized to either treatment-as-usual group or a modified version of the Cogmed program (MCT) that is suitable for use in a hospital setting (duration = 3 daily 35-min sessions for 10 weeks).
- Trial name
- CMH (NCT02610244)
- Testing
- Modified Cogmed Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Cambridge Memorial Hospital
Attention Deficit Hyperactivity Disorder, Problem Behavior
Stimulant Effects on Disruptive Behavior
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an…
- Trial name
- NCT03420339
- Testing
- Stimulant
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
ADHD
Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention
An initial evaluation of Little Flower Yoga for Kids will be conducted in a small sample of 18-30 Kindergarten and First Grade students (3-5 per class) enrolled in Girls Preparatory Charter School of the Bronx.
- Trial name
- NCT02829528
- Testing
- Little Flower Yoga For Kids
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University