Clinical trials: Drive
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Drive, Recidivism
Teen Driving Translation Study (NIH)
To translate our evidence-based, parent-engagement safe teen driving intervention to a high-risk, rural and urban teen drivers with a traffic violation, and to test the implementation, effectiveness, and cost-effectiveness of the…
- Conditions
- Drive, Recidivism, Communication, Feedback, Psychological
- Trial name
- NCT05696353
- Testing
- In-vehicle Device, Expert-Delivered Parent Communication Training, Peer-Delivered Parent Communication Training
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Ginger Yang
Cystic Fibrosis
A Short-term Comparative Study of Aerosure for Airway Clearance in Patients With Cystic Fibrosis
This is a double-blind randomised controlled crossover study to investigate whether high frequency airflow oscillation (HFAO), delivered using Aerosure, improves sputum clearance in patients admitted to hospital with infective…
- Trial name
- NCT01923753
- Testing
- Aerosure at 15 Hz, Aerosure at 25 Hz
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Actegy Ltd.
Stroke, Stroke (CVA) or Transient Ischemic Attack
Optimized Recruitment to Drive Equitable Research in Stroke, Empowering Decision-making (ORDERed)
Stroke is a major health issue, especially for women, who are more likely than men to have worse outcomes and lower quality of life after a stroke.
- Trial name
- ORDERed (NCT07576647)
- Testing
- Supported, women-centred and aphasia-friendly recruitment process (ORDERed), Traditional recruitment processes (TRADITIONAL)
- Where
- 3 sites in Canada
- Volunteers
- 1,600 people
- Sponsor
- McMaster University
Febrile Illness Acute, Seizures, Febrile
Respiratory Physiology in Children With Febrile Seizures.
Febrile seizures occur in 2-5% of the population and are typically limited to children between 3 months and 5 years-of-age. The pathophysiological link between increased body temperature and increased seizure susceptibility is…
- Trial name
- NCT01906619
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Apnea of Prematurity, Prematurity
Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants
This trial analyzes the effect of an olfactory stimulation with vanilla or strawberry aroma compared to placebo on desaturations and bradycardia in preterm infants with apnea of prematurity.
- Conditions
- Apnea of Prematurity, Prematurity, Infant, Premature, Diseases
- Trial name
- NOSE (NCT05878925)
- Testing
- Aroma
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Univentricular Heart, Children, Adult
Respiratory Drive in Patients With Univentricular Congenital Heart Disease
The aim is to evaluate the correlation between the respiratory control to hypercapnia at rest and the VE/VCO2 slope measured during cardiopulmonary exercise testing.
- Trial name
- NCT03818373
- Testing
- polysomnography
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Pediatric Obesity
Development of the DRIVE Curriculum to Address Childhood Obesity Risk Factors
The purpose of this study is to help overweight or obese children to maintain or reduce their body mass index (BMI) through the home-based parent training program the investigators developed called DRIVE.
- Trial name
- NCT02160847
- Testing
- DRIVE Program
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Georgia State University
Stroke, Driving Impaired
Fitness to Drive Among Stroke Patients
The goal of this observational study is to learn more about who can continue driving a car after a stroke. The focus of this study is on the relationship between cognitive abilities and fitness-to-drive.
- Trial name
- NCT06111989
- Testing
- Neuropsychological testing, On road test
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- National Institute for Medical Rehabilitation, Hungary
Sleep
Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P1 (NCT05336084)
- Testing
- Ultradian sleep/wake protocol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Palliative Therapy, Implementation Science
Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life
One of the most important obstacles to improving end-of-life care is the inability of clinicians to reliably identify those who are approaching the end-of-life.
- Conditions
- Palliative Therapy, Implementation Science, Screening, Terminal Care
- Trial name
- HOMR (NCT04171830)
- Testing
- modified Hospital One-year Mortality Risk (mHOMR)
- Where
- 13 sites in Canada
- Volunteers
- 3,536 people
- Sponsor
- Ottawa Hospital Research Institute
Drive, Recidivism
Intervention to Improve Driving Practices Among High-Risk Teen Drivers
The purpose of this study is to test the effects of an in-vehicle driving feedback technology, with and without parent communication training, on risky driving events, unsafe driving behaviors, and subsequent traffic violations…
- Conditions
- Drive, Recidivism, Communication, Feedback, Psychological
- Trial name
- projectDRIVE (NCT04317664)
- Testing
- In-vehicle device, Parent Communication
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ginger Yang
Risk-Taking, Adolescent Behavior
Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects
Adolescence is a time of biological and behavioral changes that can lead to risky and dangerous behaviors, and African-American youth are highly vulnerable to the consequences of risky behavior, including HIV/AIDS and violence…
- Trial name
- NCT03370393
- Testing
- Pathways for African-Americans' Success (PAAS)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Resuscitation, Infant, Newborn
Delivery Room Intervention and Evaluation Network
The American Academy of Pediatrics (AAP) convened the multi-center Delivery Room Intervention and Evaluation (DRIVE) Network to establish essential infrastructure to collect, coordinate, and analyze core demographic…
- Trial name
- DRIVE Network (NCT06803498)
- Testing
- Receipt of significant resuscitation intervention at birth
- Where
- United States
- Volunteers
- 3,000,000 people
- Sponsor
- American Academy of Pediatrics
Lung Neoplasms, Progression
Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer
Tumor cell plasticity (TCP) is a conubium of processes which lead to re-activation of developmental programs correlating with epithelial-to-mesenchymal transition, and ultimately leading to acquisition of stem cell properties and…
- Trial name
- NCT06409416
- Testing
- Analysis of diagnostic biomarkers
- Volunteers
- 20 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Malaria
Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive
The Odisha State Malaria Control Program (India) has introduced 'malaria camps' where teams of health workers visit villages to educate the population, enhance vector control with long-lasting insecticide nets (LLINs) and indoor…
- Trial name
- CSCMi20 (NCT03963869)
- Testing
- Malaria Camps
- Where
- India
- Volunteers
- 2,463 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sickle Cell Disease
Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)
This prospective mixed-method interview study aims to qualitatively describe the beliefs, attitudes, and informational needs around gene therapy for rare pediatric diseases among patients and parents of children with a rare…
- Trial name
- NCT05810181
- Testing
- Interview
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Cerebral Palsy
Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral Palsy
The goal of this clinical trial is to understand the effects of developmental powered mobility intervention on global development, gross motor function, and activity performance outcomes in 48 young children (ages 1-2 years) with…
- Trial name
- DRIVE (NCT07876219)
- Testing
- Permobil Explorer Mini, MORE-PT
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Drive, Adolescent Behavior
Translation Study of a Safe Teen Driving Intervention
Steering Teens Safe (STS) is an evidence-based and parent-focused intervention developed by the investigators, which aims to improve safe teen driving practices by enhancing parental communication skills.
- Conditions
- Drive, Adolescent Behavior, Risk Behavior
- Trial name
- NCT04317547
- Testing
- Steering Teens Safe (STS), Driving Feedback Technology.
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ginger Yang