Clinical trials: Dry Eye Syndrome
Dry Eye Syndromes
Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome
The main purpose of this study is to establish whether RP101 can reduce symptoms of dry eye syndrome in post-menopausal women.
- Trial name
- NCT03821415
- Testing
- RP101
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 104 people
- Sponsor
- Redwood Pharma AB
Xerostomia, Autoimmune Diseases
Study of Oral Bacteria in Patients With Dry Mouth
This study will examine the types of bacteria present in the dental plaque of patients with persistent dry mouth. Saliva is essential for digestion and swallowing and for maintaining the normal mineralization of teeth.
- Trial name
- NCT00048685
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dry Eye
Dry Eye Evaluation System Based on Bioinformatics
Dry eye is a common ocular surface disease of multifactorial etiology characterized by elevated tear osmolality and inflammation leading to a disrupted ocular surface.
- Trial name
- NCT04109170
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Huaxia Eye Hospital Group
Dry Eye, Cataract
Effect of Dry Eye Treatment on Corneal Astigmatism Measurements
This prospective single-center study evaluates the effect of dry eye disease and short-term ocular surface treatment on the agreement and repeatability of corneal astigmatism measurements in patients with age-related cataract.
- Trial name
- NCT07657858
- Testing
- Sodium Hyaluronate Eye Drops
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Evaporative Dry Eye
Comparison of Tear Evaporation Rate With DAILIES TOTAL1 and Biotrue ONEday
The purpose of this pilot study is to compare the effect of DAILIES TOTAL1, a low water content silicone hydrogel lens, and Biotrue ONEday, a high water content hydrogel lens, on the rate of tear evaporation.
- Trial name
- MALTESE (NCT04037969)
- Testing
- Nesofilcon A, Delefilcon A
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Primary Sjögren's Syndrome
Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome
This study consists of three consecutive parts. Part 1 in primary Sjögren's syndrome (pSS) patients (n=2-6) and Part 2 in healthy voluteers (n=3) are feasibility studies to assess if the selected [Zr-89]-rituximab PET/CT method…
- Trial name
- NCT02495129
- Testing
- VAY736 lower dose, VAY736 higher dose
- Sponsor
- Novartis Pharmaceuticals
Dry Eye Disease (DED)
Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults
The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults.
- Trial name
- NCT07020871
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Eye Disease
Digital Photography to Evaluate Dry Eye
Surface eye problems (problems of the cornea and conjunctiva), such as dry eye, are often evaluated using ocular surface staining - the application of a colored dye to the surface of the eye.
- Trial name
- NCT00073099
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy New Vessels on Disc
The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR)
Commonly know that one of the complications caused by Diabetes Mellitus (DM) is microangiopathy. Microangiopathy in the long term may lead to neuropathy of the corneal nerves.
- Conditions
- Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy New Vessels on Disc, Dry Eye Syndromes
- Trial name
- NCT04000789
- Testing
- Sodium Hyaluronate, Vitamin A, Vitamin E
- Volunteers
- 96 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital