Clinical trials: Dyspepsia
Gastroparesis, Dyspepsia
Longitudinal Evaluation of Gastric Emptying and Accommodation in Children With Dyspepsia
The purpose of this research is to further study the relationship between gastroparesis (GP) (a condition in which the stomach cannot empty itself of food in a normal fashion) and functional dyspepsia (FD) (frequent symptoms of…
- Trial name
- NCT05055336
- Testing
- Gastric emptying breath test, Stomach ultrasound
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Gastroparesis
Idiopathic Gastroparesis Registry Using a Predominant-Symptom Classification
The diagnosis of "gastroparesis" suggests that delayed gastric emptying is the underlying cause of symptoms, but this description fails to explain the variable presentation.
- Trial name
- NCT01173484
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Louisville
Dyspepsia
Clinical Trial for 'Shen Qu Xiao Shi' Oral Liquid in the Treatments of Children's Functional Dyspepsia
With domperidone suspension as the control, the effect of shenqu xiaoshi oral liquid on functional dyspepsia in children was evaluated objectively through multi-center, randomized, double-blind and double-simulation experiment…
- Trial name
- NCT05030116
- Testing
- Shenqu Xiaoshi oral liquid, Domperidone suspension
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Ruijin Hospital
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction
Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional…
- Conditions
- Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS), Functional Dyspepsia
- Trial name
- PIPPI (NCT07319078)
- Testing
- Gut-directed hypnotherapy, Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder
A Study of Randomized Sham-control Auricular TENS Unit Stimulation in Pediatric Functional Gastrointestinal Disorders
The purpose of this study is to see if using a micro-current through a device called a TENS (Transcutaneous Electrical Nerve Stimulator) unit helps to improve functional gastrointestinal disorder (FGID) symptoms in children by…
- Conditions
- Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder, Irritable Bowel Syndrome, Nausea
- Trial name
- NCT04247100
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Gisela Grotewold Chelimsky
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies.
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders (FGIDs), Gastrointestinal and Digestive Disorder
- Trial name
- NCT07222943
- Testing
- Guided Imagery Therapy
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Baylor College of Medicine
Gastroparesis
GI Neuromuscular Pathology Prospective Registry
In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future…
- Trial name
- NCT02165059
- Testing
- Surgical Full Thickness Biopsy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dyspepsia
Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia
The main purpose of this study is to determine if standard and investigational tests used to help diagnose and treat food allergies can provide information that will be useful in determining the cause of dyspepsia and helpful in…
- Trial name
- NCT00328679
- Testing
- in vitro and in vivo allergy testing
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Mercy Hospital Kansas City
Food Sensitivities, Headache
NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Food allergy reactions cause various health disorders in sensitive people. These reactions may be IgE-mediated,cell-mediated, energy disturbance-mediated, or a combination of the three.
- Conditions
- Food Sensitivities, Headache, Backache, Indigestion
- Trial name
- NCT00275795
- Testing
- NAET Procedures
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation
Functional Dyspepsia
Intestinal Permeability in Children/Adolescents With Functional Dyspepsia
The main purpose of this study is to evaluate whether intestinal permeability and/or serum zonulin concentration is increased in children/adolescents with functional dyspepsia (FD).
- Trial name
- NCT00363597
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Dyspepsia
A Two Week Nitazoxanidebased Quadruple Regimen
Helicobacter pylori (H. pylori) infection is a global health problem as it is associated with peptic ulcers, chronic gastritis, duodenitis, and stomach cancer.
- Trial name
- NCT02621359
- Testing
- Nitazoxanide, Levofloxacin, Doxycyclin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Functional Gastrointestinal Disorders
Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood
Background: Functional abdominal pain disorders (FAPD) are common in school-aged children; however, there is no reliable treatment. Aim: To determine the efficacy and safety of glucomannan for treating FAPD in children.
- Trial name
- NCT01495806
- Testing
- Glucomannan
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- Medical University of Warsaw
Dyspepsia, Child
Influence of Shenqu Xiaoshi Oral Liquid on Intestinal Microbiome of Children With Functional Dyspepsia
It has been confirmed that treatment with Shenqu Xiaoshi Oral liquid (SXOL) effectively improves dyspeptic symptoms and is well tolerated.
- Trial name
- NCT05515887
- Testing
- Shenqu Xiaoshi Oral liquid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Pediatric Functional Dyspepsia
Parent-administered Pediatric Tuina Versus Routine Care for Pediatric Functional Dyspepsia
Title: Parent-administered pediatric tuina with routine care versus routine care alone for pediatric functional dyspepsia: a pilot randomized controlled trial Background: Pediatric functional dyspepsia (PFD) is a common…
- Trial name
- NCT07369687
- Testing
- parent-administered pediatric tuina
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Gastroesophageal Reflux Disease With Dyspepsia Symptoms
Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms
To evaluate the efficacy of 4-week lansoprazole (Takepron) therapy for subjective symptomatic improvement in gastroesophageal reflux disease patients with dyspepsia symptoms
- Trial name
- LEGEND (NCT01990339)
- Testing
- Lansoprazole
- Volunteers
- 14,965 people
- Sponsor
- Takeda
Helicobacter Pylori Infection
Prevalence and Risk Factors of Helicobacter Pylori Infection in Children and Young Adults
Helicobacter pylori is a gram-negative bacterium that resides in the stomach and can cause inflammation leading to long-term effects, such as gastric ulcers, cancer, and lymphoma of the stomach mucosal linings Previous research…
- Trial name
- NCT05830357
- Where
- Egypt
- Volunteers
- 667 people
- Sponsor
- Sohag University
Functional Gastrointestinal Disorders
Bee Honey and Functional Dyspepsia in Children
Functional dyspepsia is a constellation of diverse gastrointestinal disturbing symptoms with multifactorial feature, varying from upper abdominal bloating to nausea and vomiting, that are not attributable to organic causes after…
- Trial name
- NCT05209646
- Testing
- Bee honey
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE)
Mucosal Impedance in Pediatric Population
Our hypothesis is that patients with GERD and/or Eosinophilic Esophagitis (EE) have lower esophageal impedance measurements when compared to patients who do not have GERD or EE.
- Conditions
- Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE), Functional Dyspepsia
- Trial name
- NCT02320981
- Testing
- Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedance
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Irritable Bowel Syndrome, Dyspepsia Chronic
Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders
Abdominal pain (AP)-associated functional gastrointestinal disorders (FGIDs), particularly Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), are common in pediatrics, and no safe and effective treatment is available.
- Trial name
- NCT02566876
- Testing
- Mixture of three Bifidobacteria
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Federico II University