Clinical trials: Ear Cartilage
Laryngomalacia, Sleep Apnea, Obstructive
Laryngomalacia, Examinations and Quality of Life in Children Before and After Treatment With Follow-up After 1 Year
Laryngomalacia is the most frequent cause of stridor in children under 1 year. The airway obstruction generates turbulent airway flow and creates the characteristic high-frequency stridor sound.
- Conditions
- Laryngomalacia, Sleep Apnea, Obstructive, Sleep Apnea, Ear, Nose and Throat Disorder
- Trial name
- NCT06464757
- Where
- 2 sites in Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ear Deformities, Acquired, Ear; Deformity, Congenital
Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures
This study evaluates the efficacy of the AuryzoN devices in the ear and nose reconstruction surgeries, both in terms of operative time and overall quality of reconstruction.
- Conditions
- Ear Deformities, Acquired, Ear; Deformity, Congenital, Microtia, Nose Deformity
- Trial name
- NCT03624608
- Testing
- AuryzoN Family of Devices
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Reconstrata, LLC
Microtia, Outcome Assessment
Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery
Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）.
- Conditions
- Microtia, Outcome Assessment, RCT, Surgery Related Complications Rate
- Trial name
- NCT06763991
- Testing
- Two-stage connection, One-stage connection
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Sichuan Provincial People's Hospital
Tympanic Membrane Perforation, Conductive Hearing Loss
Outcomes of Cartilage Tympanoplasty in Children
This study evaluates the anatomical and hearing outcomes of cartilage tympanoplasty in pediatric patients with chronic tympanic membrane perforations.
- Conditions
- Tympanic Membrane Perforation, Conductive Hearing Loss, Chronic Otitis Media
- Trial name
- NCT07866222
- Testing
- Cartilage Tympanoplasty
- Volunteers
- 35 people
- Sponsor
- Assiut University
Tympanic Membrane Perforation
Microscopic Versus Endoscopic Tympanoplasty
In this study, The investigatirs will compare surgical and anatomical outcomes of endoscopic and microscopic tympanoplasty type 1(myringoplasty) using tragal perichondrum and cartilage, and conduct a post-treatment survey…
- Trial name
- NCT06257602
- Testing
- Tragal graft tympanoplasty
- Volunteers
- 80 people
- Sponsor
- Assiut University
Microtia, Congenital, Microtia
Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction
This study aims to improve surgical outcomes for children and young adults with ear differences severe secondary to congenital conditions (like microtia, a condition where the ear is underdeveloped), trauma (such as dog bites)…
- Conditions
- Microtia, Congenital, Microtia, Microtia-Anotia, Ear Deformities, Acquired
- Trial name
- NCT07154667
- Testing
- Use of AuryzoN™ EAR 2.0 device, Hand carving
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nemours Children's Clinic
Chronic Suppurative Otitis Media, Mastoid Cavity
Study the Impact of the Mastoid and Middle Ear Volume on the Success of Type 1 Tympanoplasty in Pediatric Age, With Comparing Using Cartilage and Fascial Grafts Through This, Strength the Hypothesis of That Total Tympanometry Volume Correlates With Ventilated Mastoid Air Cells Volume on CT Scans
The goal of this observational study is to know the impact of the mastoid and middle ear volume on the success of type 1 tympanoplasty in pediatric age, with a closer view on the comparison of using cartilage and fascial grafts…
- Conditions
- Chronic Suppurative Otitis Media, Mastoid Cavity, Pneumatization, Tympanoplasty
- Trial name
- NCT07806461
- Testing
- tympanoplasty type 1, Audiological Evaluation, HRCT scan temporal bone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Prominent Ears
Analysis of Postoperative Bandage Use Protocols in Otoplasty
The aim of the study is to investigate the possible influence of different durations of use of postoperative elastic bandaging (seven days vs. thirty days) in the results of otoplasty.
- Trial name
- NCT01810497
- Testing
- Use of ear bandage
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Perforation of Eardrum.
Tympanoplasty Using Conchal Cavum Approach and Conchal Pericondrium
Tympanoplasty -- conchal cavum approach is a modification of Heermann endural approach to repair broken eardrums. The Heermann approach is a well recognized procedure, in common clinical practise for years.
- Trial name
- NCT02000843
- Testing
- tympanoplasty -- conchal cavum approach
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Cicatrix, Hypertrophic, Keloid
Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilage
So far the evaluation of scar treatment was based on subjective criteria. The patient groups were divided into treated versus non-treated. In this study we use patients undergoing ear reconstruction with autologous rib cartilage.
- Trial name
- NCT00565552
- Testing
- Silicone gel (Dermatix®)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Schleswig-Holstein
Ear Cartilage, Platelets
Use of Platelet-enriched Plasma During Auricular Reconstruction
In this study investigators are trying to determine the benefits of using platelet enriched plasma during the second stage of auricular reconstruction. The intervention will be blinded to the surgeon and the surgical team.
- Conditions
- Ear Cartilage, Platelets, Microtia-Anotia
- Trial name
- NCT03215979
- Testing
- Platelet enriched plasma administration
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Hospital General Dr. Manuel Gea González
Hearing Loss,Conductive
Half-thickness Tragal Cartilage Graft vs Temporalis Fascia Graft Tympanoplasty Type I
The rationale of this study is to find out the surgical outcome and success rates of tragal cartilage and temporalis fascia, subsequently to develop guide line in light of the results of this study for our department as our…
- Trial name
- PTA (NCT03817242)
- Testing
- Tympanoplasty using tragal cartilage graft, Tympanoplasty using temporalis fascia graft
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Lady Reading Hospital, Pakistan
Tympanic Membrane Perforation, Tympanoplasty
Comparison of Results of Myringoplasty Using Biodesign - an Otologic Graft Made From Porcine Small Intestinal Submucosa, Temporalis Fascia, or Tragal Perichondrium - a Retrospective Cohort Analysis
The goal of this observational, retrospective study is to learn whether a ready-made graft patch (Biodesign, made from porcine small intestinal submucosa) works as well as a participant's own tissue graft (such as tragal…
- Conditions
- Tympanic Membrane Perforation, Tympanoplasty, Myringoplasty
- Trial name
- Biodesign (NCT07698171)
- Testing
- tympanoplasty using Biodesign, tympanoplasty using autologous tissue graft
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Wolfson Medical Center
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Microtia, Congenital, Microtia
Rib Microtia and the Erector Spinae Plane (ESP) Block
The erector spinae plane block is a novel regional anesthetic technique that allows for analgesia of the thorax and abdomen with a peripheral nerve block.
- Conditions
- Microtia, Congenital, Microtia, Anesthesia, Local, Anesthesia
- Trial name
- NCT03729427
- Testing
- Erector Spinae Plane Block
- Where
- United States
- Sponsor
- Stanford University