Clinical trials: Effectiveness
Intervention Effectiveness, Implementation Research
Charge Your Brainzzz: Evaluation of the Effectiveness and Implementation of an Integrated Approach to Improve Dutch Teenagers' Sleep Health
Poor sleep among teenagers is a major public health issue. Studies show that in the Netherlands, nearly half of adolescents don't wake up feeling rested, one in five feel sleepy during the day, one in four regularly wake up at…
- Trial name
- NCT07371637
- Testing
- Charge Your Brainzzz
- Where
- Netherlands
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Effectiveness of Toothbrush
The Study of Parental Toothbrushing Efficacy Assessment With Triple-Headed and Single-Headed Toothbrushes in Preschool Children With Developmental Disability
The Objectives 1. To evaluate the efficacy of dental plaque removal between triple-headed and single-headed toothbrushes in preschool children with developmental disabilities through parental brushing 2.
- Trial name
- NCT07373249
- Testing
- Triple-headed toothbrush
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Pediatric Obesity, Training Effectiveness
Effects of HIIT and Concurrent HITT/Plyometric Training on Muscle-tendon Structure, Function and Metabolism in Pediatric Population With Obesity at Different Biological Maturation States (HIIT-PRO Kids).
The randomized controlled trial will compare the effects of a High-intensity interval training (HIIT) protocol versus a HIIT plus plyometric training in the muscle-tendon structure function and metabolism of the pediatric…
- Trial name
- HIIT-PRO-kids (NCT06727500)
- Testing
- HIIT plus plyometric training, HIIT
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad Nacional Andres Bello
Emotional Regulation, Examining the Emotion Regulation Effectiveness to be Given to Adolescents
Emotional Management in Adolescents
This study aims to give information about the content of the school-based emotion regulation program study designed for adolescent children to develop their emotion regulation skills.
- Trial name
- NCT06849310
- Testing
- Group that will receive emotional regulation training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Perineal Infection, Maternal Infections Affecting Fetus or Newborn
Different Perineal Preparations Before Vaginal Birth to Maternal/Neonatal Infections and Cost Effectiveness
The vaginal microbiome plays a crucial role in women's health, primarily composed of beneficial bacteria such as Lactobacillus, which help maintain an acidic environment in the vagina, preventing the growth of pathogens.
- Conditions
- Perineal Infection, Maternal Infections Affecting Fetus or Newborn, Cost Effectiveness
- Trial name
- NCT06880445
- Testing
- Povidone-Iodine (PVP-I), Water
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tzu-Ying Huang
Inflamed and Infected Primary Molars in Children, Effectiveness of Buffered Local Anesthesia During Dental Extraction
Evaluate Buffering Local Anesthetic in Inflamed Teeth
This randomized, double-blinded, split-mouth clinical trial evaluates the effect of buffering local anesthetic with sodium bicarbonate in pediatric dental extractions.
- Trial name
- NCT07120594
- Testing
- Unbuffered lidocaine 2% with epinephrine 1:80,000, Buffered lidocaine 2% with epinephrine 1:80,000
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Latakia University
Training Effectiveness, Fatherhood Transition Training for New Fathers
Effects of a Nurse-Led Transition to Fatherhood Program on Fathers' Involvement in Infant Care, Gender Perception, and Father-Infant Bonding
Fatherhood transition programs led by nurses can positively influence fathers' involvement in infant care, gender roles, and father-infant bonding.
- Trial name
- NCT07087483
- Testing
- The fathers who receive training, Fatherhood Skill Training
- Volunteers
- 80 people
- Sponsor
- Akdeniz University Hospital
Training Effectiveness, Motor Skills Development
Different Types of Feedback in Sports
The aim of the study is to examine the effects of mixed (visual + verbal) feedback, visual feedback and verbal feedback methods applied to gymnasts between the ages of 7-11 on the front scale, back scale (knee-knee), back scale…
- Conditions
- Training Effectiveness, Motor Skills Development, Motor Learning
- Trial name
- NCT07082647
- Testing
- Mixed feedback method, Visual feedback method, Verbal feedback method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Internet-based Intervention, Depression
Treatment Outcomes and Predictive Factors of the Effectiveness and Adherence of Moodpep: an Online Self-help Intervention for College Students With Depressive Symptoms
Depressive symptoms are prevalent among college students and often remain untreated. E-health interventions may help overcome treatment barriers by offering accessible and flexible support.
- Conditions
- Internet-based Intervention, Depression, Adherence, Predictors
- Trial name
- NCT07030244
- Testing
- Moodpep
- Where
- 2 sites in Netherlands
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Suture Techniques, Training Effectiveness
Online vs. In-Person Suturing Training: A Non-Inferiority Randomized Controlled Trial in a Low-Resource Setting
The goal of this clinical trial is to assess whether online suturing training is non-inferior to in-person training in developing suturing skills among medical students at Yarmouk University in a low-resource setting.
- Conditions
- Suture Techniques, Training Effectiveness, Online Education, Student Education
- Trial name
- RCT (NCT07038525)
- Testing
- Suturing training
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Diala Burjak
Intervention Effectiveness, Practice-based Evidence
Strengthening Family Coping Resources Open Trials
Strengthening Families Coping Resources (SFCR) Open Trials completes the second stage of the National Institute on Drug Abuse's intervention development model by testing a new family, skills-based intervention involving pre-post…
- Conditions
- Intervention Effectiveness, Practice-based Evidence, Posttraumatic Stress Disorder
- Trial name
- SFCR (NCT01754610)
- Testing
- Strengthening Family Coping Resources (SFCR)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
PrEP, HIV Prevention
The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms
The investigators aim to 1) speed up access to and delivery of PrEP to young women, and 2) compare interventions to support and maximize the prevention-effective use of PrEP.
- Conditions
- PrEP, HIV Prevention, Adolescence, Cost-effectiveness
- Trial name
- NCT03977181
- Testing
- Group-based Community Health Club, Individual-based Adherence Support
- Where
- South Africa
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Training Effectiveness, Training
Forensic Case and Forensic Evidence Management Training: Paramedic Student Example
This study aimed to provide forensic case and evidence management training to paramedic students and to evaluate the effect of the training on the knowledge level of the students.
- Conditions
- Training Effectiveness, Training, Student Education
- Trial name
- NCT06936085
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Uludag University
Training Effectiveness, Nurse's Role
Effectiveness of an Interactive Training Program on Emergency Management Competencies Among New Nurses in China
Background Effective emergency management is essential for ensuring optimal patient outcomes, with newly enrolled nurses playing a crucial role in the early detection and intervention of critical conditions.
- Trial name
- NCT06871813
- Testing
- combined the CDIO model with escape room pedagogy
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Wenzhou Central Hospital
Influenza Vaccine Effectiveness
A Case Control Study of the Effectiveness of Q/LAIV Versus Inactivated Influenza Vaccine and No Vaccine in Subjects 2-17 Years of Age
This is a post-marketing case-controlled study of the effectiveness of a quadrivalent live attenuated influenza vaccine (Q/LAIV/FluMist® Quadrivalent) versus Inactivated Influenza Vaccine (IIV) and No Vaccine in subjects 2-17…
- Trial name
- ICICLE (NCT01997450)
- Where
- 12 sites in United States, United Kingdom
- Volunteers
- 4,121 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
HIV, Hypertension
SEARCH SAPPHIRE Phase A: A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa
The randomized trials in this record will assess effectiveness, fidelity and cost of prevention and treatment interventions for HIV and hypertension with the objective of informing a population-based study of multi-sectored…
- Conditions
- HIV, Hypertension, Alcohol Drinking, Maternal Child Health
- Trial name
- SAPPHIRE PhA (NCT04810650)
- Testing
- Mobility Dynamic Treatment Intervention, Health Living Intervention for Heavy Alcohol Users, Hypertension Linkage
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 2,233 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block
Comparison of the Computer Controlled and Conventional Local Anesthesia Techniques in Primary Molar Extraction in Children Aged 5 to 9 Years Old
The goal of this clinical trial is to assess pain perception, child stress level and compare the effectiveness between periodontal ligament anesthesia using Computer-controlled Local Anesthetic delivery system and the…
- Conditions
- Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block, Pain Perception, Anesthesia Effectiveness
- Trial name
- RCT (NCT06669039)
- Testing
- Computer-controlled Local Anesthetic delivery system, Inferior Alveolar Nerve Block
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pain Score Reduction, Effectiveness of Acetaminophen
Effectiveness Of Intravenous Vs Rectal Acetaminophen For Pain Management In Post Operative Neonates
This randomized controlled trial aims to evaluate the effectiveness of intravenous (IV) versus rectal acetaminophen for postoperative pain management in neonates.
- Conditions
- Pain Score Reduction, Effectiveness of Acetaminophen, Postoperative Pain Management in Neonates, Rescue Analgesia
- Trial name
- NCT06638086
- Testing
- Acetaminophen Suppositories, Acetaminophen Injection
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Rawalpindi Medical College
Treatment Effectiveness
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
The trial tends to evaluate the efficacy of vonoprazan-based triple therapy in eradicating H. Pylori infection in adolescent patients in Egypt, in comparison to standard treatment regimens to determine if it offers superior…
- Trial name
- NCT06162949
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 242 people
- Sponsor
- Alexandria University
To Compare the Effectiveness of Hydrotherapy Versus Aerobic Exercise on Pulmonary Function in Hemiplegic Children With Cerebral Palsy
Effect of Hydrotherapy Versus Aerobic Exercise on Pulmonary Function on Hemiplegic Cerebral Palsied Children
Cerebral palsy (CP) is the most common motor disability in childhood. Respiratory muscle weakness and a low upper to lower chest diameter ratio are common respiratory dysfunction manifestations in those children which negatively…
- Trial name
- NCT06086678
- Testing
- Conventional physical therapy, Hydrotherapy, Aerobic exercise
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- South Valley University