Clinical trials: Effects of Heat
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant
rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
This is a phase I, open label, plus expansion clinical trial evaluating the safety and tolerability of rHSC-DIPGVax in combination with BALSTILIMAB and ZALIFRELIMAB.
- Trial name
- NCT04943848
- Testing
- rHSC-DIPGVax, Balstilimab, Zalifrelimab
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Physical Activity Attitude, Health Behavior
Trust in Institutions, Environment, and Physical Activity
Trust is the willingness of people to cooperate. Although much research has been conducted on physical activity, little research has explored trust in institutions regarding environmental and physical activity recommendations.
- Conditions
- Physical Activity Attitude, Health Behavior, Trust
- Trial name
- TrustAndMove (NCT07472569)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Neonatal Adaptation
Polyethylene Body Bags as an Alternative to Radiant Heat Lamp During the Neonatal Adaptation in Infants Older Than 29 Weeks
INTRODUCTION: Hypothermia in the newborn causes morbid conditions. In developing countries in the basic technology for neonatal adaptation may not be available.
- Trial name
- NCT02250079
- Testing
- polyethylene plastic bag, Conventional treatment
- Where
- Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Diarrhea, Upper Respiratory Infections
Children Immune Functions
The purpose of the planned study is to investigate the effect of heat-treated lactobacilli on diarrhea outcome in healthy children 1-4 years old in a randomized, double-blind, placebo-controlled study.
- Trial name
- NCT01717534
- Where
- 2 sites in Mexico
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cardiac Transplantation
Outcomes in Pediatric Heart Transplant Recipients Receiving Cellcept
The survival of children who have received heart transplants has greatly improved over the last ten years. One reason for this is better control over rejection.
- Trial name
- NCT00166153
- Testing
- Mycophenolate Mofetil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Sleep Apnea
Measuring Breathing Airflow Using a Heat Sensitive Camera (ThermFlow)
ThermPaed is a Sheffield Children's Hospital research collaborative which investigated the clinical diagnostic capabilities of high resolution thermal imaging (HRTI) in paediatrics.
- Trial name
- ThermFlow (NCT05972161)
- Testing
- Thermal Imaging camera
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hyponatremia
Relationship Between Heat Wave and Hyponatremia
The objective of this study is to explore the relationship between moderate to severe hyponatremia and heat.
- Trial name
- NCT02012660
- Testing
- Seasonality
- Where
- Switzerland
- Volunteers
- 28,734 people
- Sponsor
- University Hospital, Geneva
Orthodontic
Comparing HANT and Conventional NiTi Archwires in Alignment
This randomized clinical trial evaluated the efficiency of two orthodontic archwire sequences for correcting maxillary anterior crowding.
- Trial name
- NCT07176871
- Testing
- Archwires
- Where
- Vietnam
- Volunteers
- 52 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Eosinophilic Esophagitis
Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial
The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic…
- Trial name
- NCT06381219
- Testing
- Implementation of cow's milk in decreasingly heated forms, Implementation of hen's egg in decreasingly heated forms
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cutaneous Leishmaniasis
Pilot Study Using a Heat Pack to Treat Cutaneous Leishmaniasis
Current standard therapies with chemotherapy (CT) for Cutaneous Leishmaniasis (CL) are expensive, toxic/allergenic, frequently ineffective, burdensome, and often unavailable.
- Trial name
- HECT (NCT01277796)
- Testing
- Heat pack conduction-heat therapy
- Sponsor
- Universidad Peruana Cayetano Heredia
Abdominal Hysterectomy for Benign Disease
Electrosurgical Bipolar Plasmakinetic Vessel Sealing During Abdominal Hysterectomy: A Randomized Controlled Trial
Objective: To compare the safety and efficacy of the use of bipolar plasmakinetic vessel sealing (Gyrus Pk) usage versus standard technique when performing total abdominal hysterectomy for benign disease.
- Trial name
- PKAHRCT (NCT00654849)
- Testing
- Plasmakinetic bipolar energy forceps, Abdominal Hysterectomy with traditional suture technique
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Hospital de Concentracion Norte de Petroleos
Exertional Heat Illness
Risk Factors for Exertional Heat Illness
The arduous nature of military training and operations require personnel to encounter high heat load, e.g., during intense physical exertion, particularly in the heat.
- Trial name
- NCT04979455
- Testing
- Core temperature monitoring, Questionnaires, Heart rate monitoring
- Where
- United Kingdom
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Safety of Intervention, Efficacy of Intervention
Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.
Aim of this study is to compare two methods of pleurodesis for refractory malignant pleural effusions, in terms of safety and efficacy.
- Conditions
- Safety of Intervention, Efficacy of Intervention, Cost Effectiveness
- Trial name
- NCT01409551
- Testing
- VATS hyperthermic chemoperfusion, Bedside talc slurry pleurodesis
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theagenio Cancer Hospital
Malaria, Seizures
Aggressive Antipyretics for Fever Reduction in CNS Malaria
The study will examine whether prophylactic and scheduled treatment with acetaminophen and ibuprofen can decrease the maximum temperature experienced during the acute illness in children with CNS malaria.
- Conditions
- Malaria, Seizures, Coma, Parasitemia
- Trial name
- NCT03399318
- Testing
- Acetaminophen, Ibuprofen
- Where
- 3 sites in Malawi, Zambia
- Volunteers
- 256 people
- Sponsor
- University of Rochester
Advanced Solid Malignancies
Analysis of Pharmacodynamic Changes With AUY922A, an HSP90 Inhibitor
The principal research objective of this additional research protocol is to support the collection, storage and use of tumour and surrogate (peripheral blood mononuclear cells - PBMNCs).
- Trial name
- NCT01024283
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Verruca (Warts)
A Comparative Study of Occlusive Heat Patch in the Treatment of Warts
The goal of this study is to determine the safety and efficacy of the occlusive heat patch for the treatment of verrucae (warts).
- Trial name
- NCT01746056
- Testing
- Occlusive Heat Patch
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Yale University
Scar
Fractional Photothermolysis for the Treatment of Burn Scars
The aim of our study is to determine the effect of fractional photothermolysis laser in the treatment of burn scars.
- Trial name
- NCT01005992
- Testing
- Fractional laser treatment, Standard scar management
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Clinica las Condes, Chile
Patients Who Had Undergone Partial or Complete Maxillectomy
Using Flexible Resin in Maxillary Obturators
Ten patients who had had maxillectomy will be assigned to two groups employing two types of 'temporary obturators. The obturators in the first group will be made from heat cure acrylic resin, whereas those in the second group…
- Trial name
- NCT02482064
- Testing
- Flexible resin
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University