Clinical trials: Efficiency
Orthodontic Brackets
Digital Bonding vs. Direct Bonding Study
This is a prospective, 2-armed, randomized, multi-site clinical study to demonstrate that digital bonding is a more efficient treatment method than direct placement of brackets.
- Trial name
- NCT06266130
- Testing
- Treatment Group Digital Bonding Tray, Control Group Direct Bonding
- Where
- 5 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Fanconi Anemia
FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector
This is a Phase I/II clinical trial of gene therapy for treating Fanconi anemia using a self-inactivating lentiviral vector to functionally correct the defective gene.
- Trial name
- NCT03351868
- Testing
- Gene-modified autologous stem cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Optimize PBSC Harvest Through Automated Buffy Coat
Biological Variables Affecting CD34+ Peripheral Cells Collection Efficiency
All procedures performed during the study will comply with current clinical practice, international and national guidelines. Main object of the study is the PBSC apheresis procedure performed by using the continuous mononuclear…
- Trial name
- CD34+CE_2023 (NCT06308133)
- Testing
- apheresis procedure
- Where
- Italy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Orthodontic Anchorage Procedures, Orthodontic Space Closure
Miniscrews as Anchorage Device for Orthodontic Treatment
The purpose of this trial is to study and compare two different anchorage techniques. Adolescent patients in need for orthodontic treatment are randomized into Group A and B.
- Trial name
- NCT02644811
- Testing
- Topical anesthesia (buccal and palatal), Local anesthesia (buccal and palatal), Extraction of the maxillary first premolars
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Region Gävleborg
Immature Permanent Teeth With Open Apex, Pulp Necrosis
Efficiency of Asiaticoside as Intracanal Medication in Revascularization Process
This study assess the ability of Asiaticoside based Intracanal medication compared to the commonly used Intracanal medicament ( calcium hydroxide Ca(OH) 2) on the outcome of the revascularization process in immature permanent…
- Trial name
- NCT07802340
- Testing
- Intracanal medication
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Air Pollution, Indoor
The Clean Air Study: HEPA Purifiers to Improve Indoor Air Quality and Health in Rural Alaska Homes
Alaska Native children experience a high burden of respiratory disease, especially those in the Yukon-Kuskokwim (YK) Delta. Studies have shown that things like wood stove use, poor ventilation, and indoor tobacco smoke exposure…
- Trial name
- NCT06534385
- Testing
- Air purifier
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
NSCLC (Advanced Non-small Cell Lung Cancer), Adaptive Radiotherapy
Efficiency of Contemporary Off-line Adaptive Radiotherapy for Lung Cancer
Locally advanced non-small cell lung cancer (LA-NSCLC) patients could benefit in overall and progression-free survival from regular dosimetric treatment plan adaptations during radiotherapy.
- Trial name
- ECLAIR (NCT07259447)
- Testing
- CBCT-based adaptive radiotherapy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anesthesia, Supraglottic Airway Efficiency
Clinical Efficacy Evaluation of Supraglottic Airway Device SafeLM™ in Paediatric Population
The goal of this interventional study is to evaluate the clinical efficacy of SafeLM™, a video laryngeal mask airway device in paediatric population. The main questions it aims to answer are: 1.
- Conditions
- Anesthesia, Supraglottic Airway Efficiency, Paediatric Airway Management
- Trial name
- NCT07266389
- Testing
- SafeLM™ as the airway management device during general anaesthesia
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Dental Phobia, Dental Anxiety
Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe
The study was conducted among a group of dental patients aged (6-8 years old) of both genders to assess the following variables in the needleless interparliamentary anesthesia (NUMBEE) compared to traditional local anesthesia: 1.
- Conditions
- Dental Phobia, Dental Anxiety, Anesthesia, Local, Needle Phobia
- Trial name
- NCT05899296
- Testing
- dental syringe ( NumBee), Traditional dental syringe
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duaa Kamal Naji
Class I Malocclusion
Compartive Evalution of the Efficiency of Maxillary Canine Retraction Using Power Chain Versus Burstone T-loop
evaluate and compare the efficiency between elastomeric chains and burston T-loop retractors in terms of rate of maxillary canine retraction and canine movements
- Trial name
- NCT05882526
- Testing
- BURSTONE T-LOOP
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Mansoura University
Pulmonary Disease, Chronic Obstructive
European Quality of Care Pathways Study on Chronic Obstructive Pulmonary Disease (COPD)
Care pathways, a complex intervention to (re)organise, standardize and evaluate care processes, are used worldwide and in different kinds of settings. Although their international use, the impact is unclear.
- Trial name
- EQCP-COPD (NCT00962468)
- Testing
- COPD evidence based care pathway
- Volunteers
- 342 people
- Sponsor
- European Pathway Association
Task Performance and Analysis, Efficiency
Efficiency of Task Switching and Multi-tasking
This study will collect observational data on how well pediatric residents handle interruptions to their daily workflow. Residents will be directly observed during their work day and behaviors will be recorded using an electronic…
- Trial name
- NCT03685266
- Testing
- Observation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Carpal Tunnel Syndrome (CTS)
Clinical Efficiency Testing of Extracorporeal Radial and Focused Shock Wave Therapy in Patients With Mild to Moderate Carpal Tunnel Syndrome
The aim of the project is to test the efficacy of extracorporeal shock wave therapy (radial + focused) on clinical outcomes in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT06912893
- Testing
- radial shock wave therapy, focused shock wave therapy
- Volunteers
- 60 people
- Sponsor
- University Hospital St. Polten
Lipomatosis, Multiple Symmetrical
Evaluation of Safety and Efficiency of Metreleptin Treatment for Patients With Multiple Symmetric Lipomatosis (MSL)
Participants (homozygous MFN2 [gene that provides instructions to produce the Mitofusin 2 protein] R707W) will be treated with Metreleptin, and effects on body composition, metabolic parameters and safety will be assessed over a…
- Trial name
- NCT05351164
- Testing
- Metreleptin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Muscle Injury, Pulsed Electromagnetic Therapy
Investıgatıon of The Effıciency of Pulsed Electromagnetıc Field Therapy and Stretching Exercises
In this study, a total of 69 Wistar Albino rats were used, five of which were in the preliminary study. The preliminary study was planned to determine the ideal PEMF treatment time.
- Conditions
- Muscle Injury, Pulsed Electromagnetic Therapy, Muscle Stretching Exercise
- Trial name
- NCT05988476
- Testing
- Exercise, Pulsed Electromagnetic Field Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Suleyman Demirel University
Malocclusion of Anterior Teeth
Comparison of Alignment Efficiency of Steel Vs Elastomeric Ligatures In Lower Anterior Teeth
To compare the treatment time required by elastomeric ligatures and steel ligatures, in days, to achieve complete alignment of the lower anterior teeth.
- Trial name
- NCT07014332
- Testing
- Steel ligature, Elastomeric ligature
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Khyber College of dentistry
Macrophage Activation Syndrome
Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome（MAS）
The investigators evaluate the effectiveness and safeness of low-dose Recombinant Human Interleukin-2 （rhIL-2） for MAS.
- Trial name
- NCT02569463
- Testing
- Interleukin-2
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Peking University People's Hospital
Cystectomy, Robotic Surgical Procedures
Time Efficiency of Intracorporeal Orthotopic Diversion With Robotic Staplers After Robot Assisted Radical Cystectomy
Objectives and Specific Aims Time efficiency of robot assisted radical cystectomy (RARC) with totally intracorporeal stapled orthotopic neobladder remains a main drawback of this procedure.
- Conditions
- Cystectomy, Robotic Surgical Procedures, Surgical Staplers
- Trial name
- NCT02665156
- Testing
- Intracorporeal stapled neobladder using robotic staplers
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Regina Elena Cancer Institute
Cancer, Child, Only
Technology-Based Psychosocial Empowerment Program for Home Care of Children With Cancer and Their Parents
This research was planned to evaluate the effectiveness of the technology-based psychosocial empowerment program for home care for children aged 8-18 years with cancer and their parents as a parallel-group randomized controlled…
- Conditions
- Cancer, Child, Only, Empowerment
- Trial name
- NCT05566951
- Testing
- Psychosocial program, Standart care
- Volunteers
- 72 people
- Sponsor
- Gazi University
Learning Outcome, Training Efficiency
The Effects of Virtual Reality Ultrasound Training in Pairs Compared to Training Alone
Virtual Reality (VR) simulation has enabled high-quality, safe and efficient training of medical health care providers. However, training costs are considerable and may be optimized using interventions to improve learning.
- Trial name
- NCT01703975
- Testing
- Training in pairs (Dyad training)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet