Clinical trials: Electrocorticography
Sleep, Neuromodulation
The Effect of Thalamic Stimulation on Sleep Oscillations
The thalamus plays a key role in supporting sleep and is also a target of therapeutic stimulation. This project investigates when, where, and how electrical stimulation delivered to the thalamus in humans elicits or disrupts…
- Trial name
- NCT07217080
- Testing
- Effect of Electrical Stimulation on Sleep
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Brain Injury, Neurosurgery
Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI)
A single centre IDEAL Stage 1 feasibility study using novel electrophysiological recording techniques in adult participants undergoing neurosurgery.
- Conditions
- Brain Injury, Neurosurgery, Brain Ischemia
- Trial name
- EMBRI (NCT06409806)
- Testing
- ECOG Array
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University College, London
Focal Epilepsy, Intraoperative Monitoring
High-density Flexible μECoG for Epilepsy Surgery - A Single-Arm ECT
What's the clinical value of high-density flexible microelectrocorticography (μECoG) for guiding the resection of epileptogenic zone (EZ) in epilepsy surgery?
- Trial name
- Epi-PRECISE (NCT07656857)
- Testing
- Using High-density Flexible microElectrocorticography for intraoperative monitoring
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Beijing Tiantan Hospital
Epilepsy, Brain Tumor
Effect of Different Anesthetic Drugs on Electrocorticography (ECOG).
Prospective, double-blind, randomized-controlled study for pediatric cases scheduled for brain tumor excision with the aid of electrocorticography (ECOG).
- Trial name
- ECOG-Anaes (NCT07165262)
- Testing
- Fentanyl (IV), Ketamine (0.5 mg/kg)
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Epilepsy
The Role of Intracranial Electroencephalography (IEEG) in the Localization of Epileptogenic Zones (EZ) and Its Relationship With Prognosis
The mechanism of epilepsy pathogenesis is complex and not fully defined, and about 20-30% of patients with seizures that cannot be completely controlled by drugs become drug-resistant epilepsy.
- Trial name
- NCT05443958
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Refractory Localization-related Epilepsy
A New Method for Delineation of Epileptic Brian Tissue During Epilepsy Surgery (The HFO Study)
Epilepsy occurs in 0.5-0.7% of the population, of which 25% are children. 30% Of patients with focal epilepsy do not respond well to medication and half of them are eligible for epilepsy surgery.
- Trial name
- NCT02207673
- Testing
- Tailoring of the resection based on biomarker in aEcoG during epilepsy surgery
- Where
- 2 sites in Netherlands
- Volunteers
- 78 people
- Sponsor
- UMC Utrecht