Clinical trials: Emergence From Anesthesia
Neuromuscular Blockade, Delayed Emergence From Anesthesia
Sugammadex Timing and Recovery Profile in Pediatric Adenotonsillectomy
Sugammadex is routinely used to reverse rocuronium-induced neuromuscular blockade in children. In clinical practice, it is given either while the child is still deeply anesthetized or after the anesthetic has lightened.
- Conditions
- Neuromuscular Blockade, Delayed Emergence From Anesthesia, Emergence Agitation
- Trial name
- SUGA-PED (NCT07902193)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Namik Kemal University
Anesthesia, Pediatric Surgery
Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric Surgery
The main objective of this study is to study the impact of intravenous dexmedetomidine combined with locoregional anesthesia on postoperative pain in children undergoing surgery.
- Trial name
- DEXPED (NCT06736483)
- Testing
- Dexmedetomidine, Face Legs Activity Cry Consolability scale, Post-Hospitalization Behavior Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Emergence Delirium, Emergence Agitation
Remifentanil vs Fentanyl in Children 7-12 After Urologic Surgery: Emergence Delirium and Recovery Quality
Emergence delirium (agitation) is a common complication in children recovering from general anesthesia, especially after sevoflurane.
- Conditions
- Emergence Delirium, Emergence Agitation, Anesthesia Recovery Period, Postoperative Complications
- Trial name
- NCT07800845
- Testing
- Opioids
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Konya City Hospital
MRI Sedation, Pediatric Sedation
Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
The most common imaging procedure requiring sedation/anesthesia for the pediatric population is magnetic resonance imaging (MRI). However, the optimal anesthetic/sedation plan has not been determined for these procedures.
- Conditions
- MRI Sedation, Pediatric Sedation, Propofol Dosage, Emergence Delirium, Anesthesia
- Trial name
- NCT07369128
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg, Propofol (IV) 2-4 mg/kg, Dexmedetomidine (IV) 1 mcg/kg
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Boston Children's Hospital
Postoperative Residual Curarization, Neuromuscular Block Prolonged
Postoperative Residual Neuromuscular Block and Passive Smoke Exposure in Pediatric Dental Patients
Postoperative residual neuromuscular block (PRNB) may persist despite apparent clinical recovery from neuromuscular blockade and may increase the risk of postoperative respiratory complications.
- Trial name
- NCT07831434
- Testing
- Passive Smoke Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Agitation, Emergence Delirium, Anesthesia
Impact of Neuromonitoring on Postoperative Agitation in Pediatric General Anesthesia
Postoperative agitation is frequently observed in the pediatric patient group following general anesthesia. The exact cause of this agitation has not been clearly determined; however, it may be associated with various factors…
- Trial name
- NCT07243990
- Testing
- dsa intervention group, Traditional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sakarya University
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia Recovery, Pediatric Anesthesia
Recovery Trajectories After Propofol-Based Intravenous Anesthesia in Toddlers and Older Children
This observational study aims to compare how quickly and smoothly younger children (ages 3 to 6 years) recover from general anesthesia compared to older children (ages 6 to 12 years).
- Conditions
- Anesthesia Recovery, Pediatric Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07766629
- Volunteers
- 64 people
- Sponsor
- Assiut University
Postoperative Delirium, Pediatric Anesthesia
Inflammatory Biomarkers and Postoperative Delirium in Pediatric Circumcision
Postoperative delirium may occur in children after general anesthesia, even following short procedures such as circumcision. Preoperative systemic inflammation has been associated with postoperative delirium in adults, but data…
- Conditions
- Postoperative Delirium, Pediatric Anesthesia, Inflammatory Biomarkers
- Trial name
- NCT07323485
- Testing
- Measurement of Preoperative Inflammatory Biomarkers
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Emergence Delirium, Pediatric Dental General Anesthesia
Pre-emptive Local Anesthesia and Emergence Behavior After Pediatric Dental General Anesthesia
This study will evaluate whether pre-emptive local anesthesia improves early recovery after ambulatory pediatric dental general anesthesia.
- Conditions
- Emergence Delirium, Pediatric Dental General Anesthesia, Postoperative Recovery
- Trial name
- PEDLA-QOR (NCT07604337)
- Testing
- Pre-emptive Local Anesthesia, Articaine Hydrochloride With Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- seher orbay yasli
Emergence Delirium, Anesthesia, Preschool Age Children
Influence of Intraoperative Auditory Intervention on Emergence Delirium in Preschoolers: A Randomised Controlled Clinical Trial
Emergence delirium (ED), characterized by disorientation and altered cognitive behavior, is a common postoperative complication in pediatric surgery.
- Conditions
- Emergence Delirium, Anesthesia, Preschool Age Children, Emergence Agitation
- Trial name
- NCT07630922
- Testing
- Classical Music Group, Mother's Heartbeat Recording Group, Mother's Lullaby Recording Group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Henan Provincial People's Hospital
Tonsillitis, Post-operative Nausea and Vomiting (PONV)
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham.
- Conditions
- Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction
- Trial name
- NCT06326983
- Testing
- Dexmedetomidine, Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Children's Hospital
Pediatric Anesthesia, Preoperative Anxiety
Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery
This study aims to compare the effects of intranasal dexmedetomidine and oral midazolam as premedication in pediatric patients undergoing elective inguinal and urological surgery under general anesthesia.
- Conditions
- Pediatric Anesthesia, Preoperative Anxiety, Emergence Agitation
- Trial name
- NCT07565116
- Testing
- Dexmedetomidine, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Anesthesia, Neuromuscular Blockade
International Focus Group Discussion on Neuromuscular Monitoring.
Focus-Group based discussion designed to gain more in-depth information on factors that could lead to an increase in the adoption of neuromuscular monitoring taking into account different country-specific contexts.
- Conditions
- Anesthesia, Neuromuscular Blockade, Neuromuscular Block, Residual, Perioperative/Postoperative Complications
- Trial name
- NCT06945341
- Testing
- Focus-Group discussion
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Postoperative Pain, Preoperative Anxiety
Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery
The goal of this observational study is to learn if preoperative anxiety levels can predict the quality of early postoperative recovery, pain intensity, and the occurrence of emergence delirium in pediatric patients aged 2 to 7…
- Conditions
- Postoperative Pain, Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia, Urogenital Diseases
- Trial name
- NCT07343388
- Testing
- Standardized Perioperative Management and Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Aydin Adnan Menderes University
Emergence Delirium, Anesthesia
The Effect of EEG and BIS-guided Anaesthesia on the Incidence of Emergent Delirium in Children
The aim of the study is to compare two modalities of measuring the depth of general anaesthesia on the incidence of emergent delirium in children.
- Trial name
- NCT07534215
- Testing
- EEG monitoring, BIS monitoring
- Where
- Czechia
- Volunteers
- 540 people
- Sponsor
- University Hospital Ostrava
Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia
The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients
Emergence delirium is a common complication in pediatric patients undergoing general anesthesia. The aim of this study is to investigate the incidence of postoperative awakening delirium and agitation in pediatric patients aged…
- Conditions
- Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia, Postoperative Agitations in Pediatric Patients, Postoperative Nausea and Vomiting (PONV)
- Trial name
- NCT07534956
- Testing
- propofol ( Paedfusor Model), propofol (Eleveld Model), Sevofluorane
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital