Clinical trials: Emergency Patients
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cyanide Poisoning
Hydroxycobalamin and Rural Emergency Medical Services Cyanide Exposure Patients: A Cost Analysis
The costs to a rural emergency medical services (EMS) system of a change from a traditional cyanide antidote kit to a kit containing hydroxocobalamin alone are currently unknown.
- Trial name
- NCT01656616
- Testing
- Cyanide antidote administration
- Where
- United States
- Sponsor
- MaineHealth
Syncope
Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Syncope is a common Emergency Department (ED) presentation but the underlying diagnosis is not apparent in 60% of patients after assessment and serious adverse event rate is 7% at one month with most having acute cardiovascular…
- Trial name
- PATCH-ED (NCT02683174)
- Testing
- Novel ambulatory patch (ZIO® XT Patch), BNP and hs-troponin I at 0 and 3 hours post ED attendance
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- NHS Lothian
HIV Infections, Syphilis Infection
Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department
The purpose of this study is to evaluate infection detection and treatment initiation rates for syphilis and HIV before and after integration of the Chembio DPP® HIV-Syphilis rapid POC test into an ongoing Emergency Department…
- Trial name
- NCT07525076
- Testing
- Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- The University of Texas Health Science Center, Houston
Emergencies
Identification of the Sick Patient in the ED
This non-interventional study will test scoring systems used to identify high risk patients when they are triaged upon presentation in the Emergency Department (ED) in a single hospital in the Northwest of England between May and…
- Trial name
- NCT03209375
- Where
- United Kingdom
- Volunteers
- 503 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Syncope
Improving Management of Emergency Department Patients With Undifferentiated Syncope: Prospective Validation of the Canadian Syncope Risk Score
Among Kaiser Permanente Northern California (KPNC) health plan members, age ≥16 years, with recent syncope and presyncope undergoing emergency department (ED) management with a point-of-care clinical decision support (CDS) tool…
- Trial name
- NCT05538143
- Testing
- Comprehensive ED syncope/presyncope management tool
- Where
- 5 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- Kaiser Permanente
Small Bowel Obstruction, Frailty
The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery.
- Conditions
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- Trial name
- NGTUBE-OBS (NCT06262815)
- Testing
- Nasogastric tube placement, Clinical Frailty Scale
- Where
- 8 sites in Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Daniel Wilhelms
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Aging
Reducing Potentially Inappropriate Medication Prescribing for Older Patients in the ED
This research is being conducted to learn which implementation strategy of EQUIPPED is most effective to improve prescribing practices of ED providers toward older Veterans and determine the factors influencing implementation of…
- Trial name
- EQUIPPED (NCT04004936)
- Testing
- EQUIPPED with Active Feedback, EQUIPPED with Passive Feedback
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Cardiac Arrest, Needle Stick
Needle Stick Injuries in Emergency Medical Service Practice
During the pandemic era, medical personnel should wear full protective suits. However, they limit the performance of medical procedures. One of the main questions is whether to use double gloves.
- Conditions
- Cardiac Arrest, Needle Stick, Injuries, Glowe
- Trial name
- NCT04363788
- Testing
- double gloves
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Lazarski University
Biliary Tract Infection
Ultrasound-guided Biliary Drainage Improving Prognosis in the Frail and High Risk Elderly Patients
Acute biliary tract infection is a kind of disease caused by bacteria of biliary tract infection, mainly including acute cholecystitis and acute cholangitis, especially acute obstructive suppurative cholangitis (AOSC),which can…
- Trial name
- NCT06960486
- Testing
- Bedside ultrasound-guided real-time biliary drainage, traditional appointment ultrasound
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hebei Medical University
Cancer
Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections
RATIONALE: White blood cells that have been treated in the laboratory may kill cells that are infected with cytomegalovirus. PURPOSE: This phase I trial is studying how well cytotoxic T cells work in treating patients who have…
- Trial name
- NCT00769613
- Testing
- cytomegalovirus IE-1-specific cytotoxic T lymphocytes, cytomegalovirus pp65-specific cytotoxic T lymphocytes, therapeutic allogeneic lymphocytes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Elderly; Renal Insufficiency
Using Informatics to Enhance Care of Older Emergency Department Patients
The subjects in this study are physicians working in the Wishard Emergency Department. The purpose of this study is to measure the extent to which information technology (i.e.-computers) improves emergency department care.
- Trial name
- NCT00297869
- Testing
- Computer-Assisted Decision Support
- Where
- United States
- Volunteers
- 1,350 people
- Sponsor
- Indiana University
Head Injury, Minor, Pediatric
Hypertonic Saline for Mild TBI in Pediatric Patients
The purpose of this study is to compare two different treatments (normal saline and hypertonic saline) for concussions to see if one makes more of a difference in symptoms that can occur following concussions.
- Conditions
- Head Injury, Minor, Pediatric, Emergency Department Patient
- Trial name
- NCT07060105
- Testing
- Hypertonic Saline ( 3% Sodium Chloride Saline), Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Texas at Austin
Emergency Patients
Analyzing Patient Flows at the Emergency Department by Data Analytics, Simulation, and Optimization
In this project, investigators apply operations research techniques, more specifically data analytics, system simulation, mathematical modelling, and optimization, for analyzing and improving operations in the Emergency…
- Trial name
- NCT05025683
- Where
- Hong Kong
- Volunteers
- 23,425 people
- Sponsor
- Chinese University of Hong Kong
Arterial Blood Pressure, Difficult Vein Access
Comparison of Traditional and Ultrasound-Guided Techniques for Vascular Access in Patients With Difficult Venous Access in Emergency Department.
The aim of this clinical trial is to compare the use of ultrasound versus the traditional palpation and visualization technique for vascular punctures, both peripheral venous and arterial punctures for arterial blood gas…
- Trial name
- PUVASECO (NCT07013994)
- Testing
- peripheral venous cannulation with ultrasound-guided technique, Arterial gas puncture using ultrasound-guided technique, Peripheral venous cannulation with traditional technique
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Mercedes Segunda Peralta Gámez
Time Until Identification of Defined Parameter
Electronic Pediatric Emergency Ruler vs the Broselow Tape.
Comparison of two different pediatric emergency rulers for length-based body weight estimation in pediatric emergencies. Primary outcome is the time needed to identify four defined parameters from the pediatric emergency rulers…
- Trial name
- ePERvsBT (NCT03953105)
- Testing
- ePER, BT
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Colon Perforation
Feasibility and Effects of an Enhanced Recovery vs Conventional Care After Emergency Colon Surgery for Patients With Left Colon Perforation.
A study was designed with a prospective cohort of all patients undergoing urgent surgery for left colon perforation between March 2014 and June 2017 who were treated according to a specific ERAS programme (ERAS group/29…
- Trial name
- NCT03611413
- Testing
- ERAS care
- Volunteers
- 50 people
- Sponsor
- Antonio Arroyo Sebastian
Asthma
Impact of Omalizumab on Corticosteroid Use, Emergency Room Visits and Hospitalizations
A retrospective database analysis to evaluate the impact of omalizumab on the use of corticosteroid, emergency-department visits and hospitalizations among patients with uncontrolled asthma and using high-dose Inhaled…
- Trial name
- NCT01460862
- Sponsor
- Novartis Pharmaceuticals
Asthma
Adequacy of Management of Patients With Asthma Exacerbation in Martinique
Asthma is a chronic respiratory disease whose goal of therapeutic, educational and preventive care is to prevent the onset of acute crisis, the most serious of which are life threatening.
- Trial name
- APEXA (NCT05253391)
- Testing
- Routine care
- Where
- 7 sites in Martinique
- Volunteers
- 339 people
- Sponsor
- University Hospital Center of Martinique