Clinical trials: Endocrine Disorders
Diabetes, Retinopathy
Telemedicine Retinal Screening Utilizing a Mobile Medical Unit
Objective: To test the accuracy of a referral system for diabetic eye disease conducted by a trained screener using a digital camera, a mobile medical unit and a centralized image-storing software in underserved, ethnically…
- Trial name
- NCT01412905
- Where
- United States
- Volunteers
- 1,229 people
- Sponsor
- Scripps Whittier Diabetes Institute
Type 2 Diabetes
Pioglitazone/Glimepiride (Sonias) Combination Tablets Special Drug Use Surveillance Survey in Patients With Type 2 Diabetes Mellitus Who Respond Poorly to Pioglitazone
The purpose of this study is to evaluate the safety and efficacy of long-term use of pioglitazone/glimepiride combination tablets (Sonias Combination Tablets LD) in patients with type 2 diabetes mellitus who respond poorly to…
- Trial name
- NCT02098746
- Testing
- Pioglitazone/glimepiride
- Volunteers
- 294 people
- Sponsor
- Takeda
Breast Cancer, Chronic Myeloproliferative Disorders
Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon
RATIONALE: Beclomethasone may be an effective treatment for graft-versus-host disease. PURPOSE: Phase I/II trial to study the effectiveness of beclomethasone in treating patients who have graft-versus-host disease of the…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease
- Trial name
- NCT00010283
- Testing
- beclomethasone dipropionate
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Type 1 Diabetes
Hypothalamo-pituitary Adrenal Axis Activity and Neuropsychological Consequences in Type 1 Diabetes in Childhood
The general objective is to precise the role of HPA axis activity in neuropsychological consequences of type 1 diabetes. The investigators hypothesize that hyperactivity of HPA axis is associated with higher scores of depression…
- Trial name
- CORTICODIAB (NCT02377583)
- Testing
- T1DM analyses
- Where
- 3 sites in France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Diabetes
Using mHealth (Mobile Health) to Optimize Glycemic Control in Adults With Type 2 Diabetes: Proof of Concept Study
The objective of this study is to evaluate the efficacy of a diet-related mHealth (mobile health) intervention on glycated hemoglobin among adults with type 2 diabetes.
- Trial name
- mHealth (NCT05013294)
- Testing
- Intervention
- Where
- Kenya
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Polycystic Ovary Syndrome
A Cooking and Eating Study
Background. The polycystic ovary syndrome (PCOS) is a complex hormonal disorder that presents in susceptible girls around the time of menarche. Females with PCOS have high levels of androgens (e.g., testosterone).
- Trial name
- ACES (NCT01079845)
- Testing
- Nutrition Education, Dietary Counseling, and Cooking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Prediabetes, Type 1 Diabetes
Diabetes Prevention - Immune Tolerance
A double-blind, randomized investigator-initiated study to determine the safety and the effect of Diamyd® on the progression to type 1 diabetes in children with multiple islet cell autoantibodies Eligible children are 4 years or…
- Trial name
- DIAPREV-IT (NCT01122446)
- Testing
- Diamyd
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University
Diabetic Ketoacidosis
Children with Diabetic Ketoacidosis
In the present work we aim to 1. Response to therapy, During the management of DKA, acid base status, glycemia, and serum electrolytes are measured frequently to monitor the efficacy of treatment, detect complications of DKA and…
- Trial name
- NCT06599203
- Volunteers
- 130 people
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2, Obesity
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
To assess whether holding incretin-based therapy before endoscopy reduces the likelihood of clinically relevant Residual Gastric Volume (RGV).
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Gastroparesis
- Trial name
- NCT06533527
- Testing
- GLP-1 medication
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Diabetes, Red Blood Cell Survival
RBC Lifespan Measurement in Diabetic Children
HbA1c, a measure of mean blood glucose over the lifespan of a red blood cell (RBC), is a marker of increasing importance both for assessing glycemic control in children with known diabetes and for the diagnosis of diabetes in…
- Trial name
- NCT03073070
- Testing
- biotin labeled RBCs
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Guohua An
Type 1 Diabetes
Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children
The purpose of this study is to see whether low blood sugar at night can be reduced by using a system that turns off the insulin pump automatically.
- Trial name
- PSO4 (NCT01823341)
- Testing
- Pump suspension algorithm
- Where
- 3 sites in United States, Canada
- Volunteers
- 97 people
- Sponsor
- Jaeb Center for Health Research
Congenital Adrenal Hyperplasia
Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia
This study is a randomized, double-blind, active-controlled, phase III study of Chronocort® compared with immediate-release hydrocortisone replacement therapy in participants aged 16 years and over with Congenital Adrenal…
- Trial name
- CONnECT (NCT05063994)
- Testing
- Chronocort, Cortef
- Where
- 21 sites in United States, France and 1 more
- Volunteers
- 55 people
- Sponsor
- Neurocrine UK Limited
Thyroid Nodule
the Effect of Universal Salt Iodization on Thyroid Diseases
1. acquire the environmental iodine status of Hangzhou 2. acquire the iodine status of population in Hangzhou 3. acquire the prevalence of thyroid diseases in Hangzhou 4.
- Trial name
- NCT01838629
- Where
- China
- Volunteers
- 12,438 people, healthy volunteers welcome
- Sponsor
- Weimin Xu
Type 1 Diabetes, Autoimmunity
Prospective Assessment in Newborns for Diabetes Autoimmunity
This is an observational study designed to help researchers understand the genetics and pathogenesis of type 1 diabetes, and to identify biomarkers for disease and disease complication prediction.
- Trial name
- PANDA (NCT00649246)
- Where
- 3 sites in United States
- Volunteers
- 25,055 people, healthy volunteers welcome
- Sponsor
- Augusta University
Type 1 Diabetes
Comparison of an Artificial Pancreas Versus Threshold Low Glucose Suspend in Type 1 Diabetic Children
The objective of this study is to assess the efficacy of an Artificial Pancreas system which includes a Control-To-Range algorithm, versus standard Insulin Pump Therapy with Threshold Low glucose Suspend feature.
- Trial name
- SHAN (NCT02509429)
- Testing
- Insulin therapy (aspart, lispro ou glulisine) with Control-to-Range algorithm, Insulin therapy ((aspart, lispro ou glulisine) withThreshold Low Glucose Suspend
- Where
- 4 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier
Papillary Thyroid Carcinoma
Humanistic Continuing Care Via WeChat for Patients Undergoing Thermal Ablation of Papillary Thyroid Carcinoma
The goal of this clinical trial is to test whether human-centered nursing care lowers emotional distress and improves quality of life for people who are awake during thyroid thermal ablation.
- Trial name
- NCT07302672
- Testing
- Humanistic Continuing Care via WeChat, Usual Care (No Structured WeChat Program)
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Ming-an Yu
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Glucose Intolerance During Pregnancy, Body Composition
- Trial name
- eMOM (NCT03681054)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Diabetes, Diabetes Mellitus, Type 2
Safety of NovoMix® 30 or Levemir® for Treatment of Type 2 Diabetics in Macedonia
This study is conducted in Europe. The aim of this observational study is to investigate the incidence of serious adverse drug reactions when using NovoMix® 30 (biphasic insulin aspart 30) or Levemir® (insulin detemir) for…
- Trial name
- NCT00842894
- Testing
- insulin detemir, biphasic insulin aspart 30
- Where
- North Macedonia
- Volunteers
- 3,421 people
- Sponsor
- Novo Nordisk A/S
Coronary Heart Disease, Diabetes
The Effect of Autonomic Neuropathy Status on the Endpoint Events in Diabetes Patients With Coronary Heart Disease and Sleep Apnea.
Background: diabetes combined with cardiac autonomic neuropathy (CAN) can denervate the heart, which may prevent patients with sleep apnea syndrome from bradycardia in the early stage, and directly show an increased risk of…
- Conditions
- Coronary Heart Disease, Diabetes, Sleep Apnea Syndrome, Cardiovascular Autonomic Neuropathy (CAN)
- Trial name
- NCT07723222
- Testing
- The total score of Ewing test (i.e. cardiovascular autonomic reflex test and heart rate variability) was ≥1, which was divided into cardiac autonomic neuropathy group (CAN grou
- Volunteers
- 326 people
- Sponsor
- Xiangtan Central Hospital
Achondroplasia
A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia
This is a Phase 3, multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of infigratinib in children and adolescents with achondroplasia (ACH) who have completed at least 26 weeks of…
- Trial name
- PROPEL3 (NCT06164951)
- Testing
- Infigratinib 0.25 mg/kg/day
- Where
- 27 sites in United States, Argentina and 8 more
- Volunteers
- 114 people
- Sponsor
- QED Therapeutics, a BridgeBio company
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.