Clinical trials: Endodontics
Endodontic Inflammation, Pulp Disease, Dental
Evaluation of Clinical and Radiological Success of Vital Amputation Treatment
Total amputation therapy; is a treatment method aimed at maintaining the vitality of the radicular pulp remaining as a result of complete removal of coronal pulp tissue.
- Trial name
- NCT03883295
- Testing
- Control, NeoMTA Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pulpitis
Vital Pulp Therapy to Treat Irreversible Pulpitis
The purpose of this study is to demonstrate non-inferiority of pulpotomy treatment (with new endodontic bio-materials) as a new treatment with one-visit root canal therapy as reference treatment in pain relief and clinical and…
- Trial name
- VPT (NCT00748280)
- Testing
- One-visit root canal therapy, pulpotomy
- Where
- Iran
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Tooth,Non-vital
Postoperative Pain Following Irrigation With Endodontic Needle, Sonic and Passive Ultrasonic Techniques
The aim of this study is to compare the postoperative pain after root canal treatment following irrigation by endodontic needle, sonic and passive ultrasonic irrigation techniques.
- Trial name
- NCT02912286
- Testing
- conventional needle irrigation, passive ultrasonic irrigation, sonic irrigation
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
randomized clinical trial which Evaluate thr Post-operative Pain Following Platelet Rich Plasma (PRP) Revascularization versus Conventional Endodontic Treatment of Non-vital Mature Mandibular Molars with Chronic Peri-apical…
- Trial name
- NCT03350841
- Testing
- Platelet rich plasma PRP, root canal treatment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effectiveness of Microscope During Apical Surgery in Endodontic Treated Teeth.
RCT: Effectiveness of a Microscope During Dental Root Apical Surgery
An endodontic treatment is the standard therapy for teeth with periapical periodontitis. The overall success rate for this treatment is high; 97% of the treated teeth are retained in the oral cavity after 8 years (Salehrabi \&…
- Trial name
- NCT01759069
- Testing
- Surgical treatment with microscope
- Where
- Netherlands
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Photochemotherapy Reaction, Dental Pulp Necrosis
Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study
Microorganisms play a critical role in the etiology and pathogenesis of apical periodontitis. Enterococcus faecalis and Candida sp. are frequently associated with persistent infections.
- Conditions
- Photochemotherapy Reaction, Dental Pulp Necrosis, Polymerase Chain Reaction, Infection
- Trial name
- NCT03212729
- Testing
- ANTIMICROBIAL PHOTODYNAMIC THERAPY, Conventional endodontic treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Chronic Apical Periodontitis, Pulp Necrosis
Clinical and Inflammatory Outcomes of Regenerative Endodontic Treatment Using Injectable Platelet-Rich Fibrin in Mature Necrotic Teeth With Chronic Apical Periodontitis.
This randomized clinical trial aims to compare regenerative endodontic treatment using injectable platelet-rich fibrin (i-PRF) with conventional root canal treatment in mature necrotic anterior teeth with chronic apical…
- Trial name
- REGEN-iPRF (NCT07913399)
- Testing
- Conventional Root Canal Treatment, Regenerative Endodontic Treatment with i-PRF, Injectable Platelet-Rich Fibrin (i-PRF)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Endodontic Disease, Regenerative Endodontics
Evaluation of Different Scaffolds in Regenerative Endodontic Treatment
The aim of this study is to evaluate and compare the regenerative potentials of Injectable Platelet-Rich Fibrin (I-PRF), Platelet-Rich Fibrin (PRF), and Blood Clot (BC) as different scaffolds regarding: Radiographic outcomes…
- Trial name
- NCT06945965
- Testing
- Injectable platelet-rich fibrin (i-PRF) scaffold, platelet-rich fibrin (PRF)scaffold, blood clot (BC) scaffold
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Regenerative Endodontics
Clinical and Radiographic Outcomes of PRF, Chitosan, and Blood Clot in Regenerative Endodontics of Molars
This clinical trial aimed to evaluate the long-term effects of using chitosan, blood clots, and platelet-rich fibrin as scaffolds in regenerative endodontics on tooth development.
- Trial name
- NCT07119619
- Testing
- Regenerative Endodontic Treatment Using a Blood Clot as a Scaffold, Regenerative Endodontic Treatment Using a Chitosan as a Scaffold, Regenerative Endodontic Treatment Using a Platelet Rich Fibrin as a Scaffold
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Inonu University
Apical Periodontitis
Lesion Healing After Regenerative Endodontic Treatment
Endodontics involves various therapeutic interventions for diagnosing, preventing, and managing pulpal and periradicular pathologies.
- Trial name
- NCT06843850
- Testing
- regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Endodontic Treatment of Primary Teeth
Mechanized Instrumentation for Endodontic Treatment of Primary Teeth
Mechanized instrumentation systems stand out amongst various devices used in modern Endodontics. Its use in Pediatric Dentistry, its action in primary teeth, has been in the center of many discussions and laboratory studies.
- Trial name
- NCT03453658
- Testing
- Manual instrumentation, Reciprocating Instrumentation
- Where
- Brazil
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Regenerative Endodontic, Apexification
Comparison of Apexification and Regenerative Endodontic Therapy: a Retrospective Study
In this study, the effects of mineral trioxide aggregation (MTA) apexification and regenerative endodontic treatment (RET) methods on periapical healing was compared with fractal analysis (FD) and periapical index (PAI).
- Conditions
- Regenerative Endodontic, Apexification, Fractals
- Trial name
- NCT05213026
- Testing
- Regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Pulp Necroses
Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency.
- Trial name
- PRF (NCT05517187)
- Testing
- no intervention, Platelet rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahda University
Apical Termination Point
Effect of Different Apical Termination Point Guided by Electronic Apex Locator on Post Endodontic Pain , A Randomized Control Trial.
This randomized control trial compares the different apical termination point by using electronic apex locator J morita root ZX on post endodontic pain patient with single rooted teeth will be randomly assigned in to three groups…
- Trial name
- NCT07642349
- Testing
- apical constriction and length determintion
- Where
- Pakistan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Prof Nazeer Khan
Pulp and Periapical Tissue Disease
Regenerative Endodontics for Non-vital Primary Molars
Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold
- Trial name
- NCT05098483
- Testing
- Regeneration in primary molars by using MTA, Regeneration in primary molars by using biodentine, Conventional Root canal treatment in primary molars
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Musculoskeletal System Disease, Position Sense Disorders
Postural and Muscle Fatigue Analysis of Endodontic Residents
Musculoskeletal disorders (MSDs) are a significant occupational health problem for dentists and have been linked to a decline in quality of life, often leading to stress-related illnesses and early retirement.
- Conditions
- Musculoskeletal System Disease, Position Sense Disorders, Symptoms and Signs, Postural; Defect
- Trial name
- NCT06282653
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Pain
Management of Post Endodontic Re-treatment Pain With Low-Level Laser Therapy
In this clinical trial investigators aimed to evaluate Post endodontic re-treatment pain after irradiation of low level laser therapy
- Trial name
- NCT03023761
- Testing
- low level laser
- Where
- Iran
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University