Clinical trials: Endophthalmitis
Cataract, Postoperative Complications
Validation of an Artificial Intelligence System for Postoperative Management of Cataract Patients
Cataract surgery is the current standard of management for cataract patients, which is typically succeeded by a postoperative follow-up schedule.
- Conditions
- Cataract, Postoperative Complications, Artificial Intelligence
- Trial name
- NCT04138771
- Testing
- An artificial intelligence system for postoperative management of cataract patients
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Endophthalmitis
Preoperative Topical Gatifloxacin on Anterior Chamber Cultures After Cataract Surgery
Postoperative endophthalmitis, a possible severe complication of cataract surgery, is an infection of the anterior chamber of the eye caused by bacterial contamination and colonization through surgical incisions.
- Trial name
- NCT00335231
- Testing
- gatifloxacin ophthalmic (ZYMAR)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Endophthalmitis
Endogenous Endophthalmitis in the Inpatient Setting
The purpose of this study is to determine the rate of endogenous endophthalmitis in patients admitted to Stanford Hospital with a systemic infection and positive blood cultures, as this may improve the clinical care of this…
- Trial name
- NCT01323868
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Stanford University
Endophthalmitis
Clinical Features and Visual Prognosis of Infectious Endophthalmitis
The aim of this observational study was to retrospectively examine the clinical data of patients with infectious endophthalmitis and to analyse their clinical characteristics.
- Trial name
- NCT06755177
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongnan Hospital
Endophthalmitis, Cataract
Early Vitrectomy for Endophthalmitis After Cataract Surgery
Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness.
- Conditions
- Endophthalmitis, Cataract, Vitreous Detachment, Retinal Detachment
- Trial name
- NCT05249413
- Testing
- Early 23-gauge pars-plana vitrectomy
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Benha University
Endophthalmitis and Orbital Cellulitis
Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19)
To report on cases presented with combined endophthalmitis and orbital cellulitis as a first presentation of covid-19 infection.
- Trial name
- NCT04456556
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Minia University
Juvenile Rheumatoid Arthritis, Uveitis
TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid Arthritis
This study will investigate the safety and effectiveness of the drug TNFR:Fc to treat uveitis (eye inflammation) in patients with juvenile rheumatoid arthritis.
- Trial name
- NCT00001862
- Testing
- Enbrel
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Eye Institute (NEI)
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Endophthalmitis
Severe Intraocular Infection
The host-immune reaction to infection is essential for the comprehension of the disease and the development of new therapies. The aim of the study is to describe intraocular cytokines network in aqueous humor using multiplex…
- Trial name
- NCT02818062
- Testing
- Cytokines dosage in Aqueous humor
- Where
- 7 sites in France
- Volunteers
- 263 people
- Sponsor
- University Hospital, Strasbourg, France
Cataracts
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
This study will test the effectiveness of an intraocular lens treated with heparin in reducing or preventing inflammation after cataract surgery in patients with uveitis.
- Trial name
- NCT00001311
- Testing
- heparin-surface modified intraocular lens
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Chlamydia Infections, Ophthalmia Neonatorum
Clinical Trial of Eye Prophylaxis in the Newborn
To compare the effectiveness of silver nitrate drops, erythromycin ointment, or no medication in preventing neonatal conjunctivitis caused by Chlamydia trachomatis and other eye infections.
- Trial name
- NCT00000120
- Testing
- Erythromycin Ointment, Silver Nitrate Drops
- Sponsor
- National Eye Institute (NEI)
Endophthalmitis, Eye Infections
Endophthalmitis Vitrectomy Study (EVS)
To determine the role of initial pars plana vitrectomy in the management of postoperative bacterial endophthalmitis. To determine the role of intravenous antibiotics in the management of bacterial endophthalmitis.
- Trial name
- NCT00000130
- Testing
- Intravitreal Antibiotics, Initial Pars Plana Vitrectomy
- Sponsor
- National Eye Institute (NEI)
Strabismus, Surgery
Povidone-iodine Antisepsis for Strabismus Surgery
The purpose of this study is to compare the efficacy of 5 % vs. 1.25 % povidone-iodine (PI) as preoperative antiseptic prior to strabismus surgery in children as a prophylaxis of endophthalmitis.
- Conditions
- Strabismus, Surgery, Endophthalmitis
- Trial name
- PASS (NCT00461656)
- Testing
- Preoperative conjunctival irrigation with 5% or 1.25% PI
- Where
- 9 sites in Germany, Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
Endophthalmitis, Endophthalmitis Postoperative
Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-Intravitreal Injection Endophthalmitis
This prospective comparative interventional study evaluated the anatomical and visual outcomes of phacovitrectomy versus pars plana vitrectomy (PPV) alone in patients with post-intravitreal injection endophthalmitis.
- Conditions
- Endophthalmitis, Endophthalmitis Postoperative, Intravitreal Injection Patients
- Trial name
- NCT07717944
- Testing
- Phacovitrectomy, Pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Endophthalmitis, Prophylaxy of Post Traumatic Endophthalmitis
Prophylaxis of Acute Post-Traumatic Bacterial Endophthalmitis
Purpose: To evaluate the efficacy of combined intraocular injection of gentamycin and clindamycin in prevention of acute posttraumatic bacterial endophthalmitis (APBE) following penetrating eye injuries.
- Conditions
- Endophthalmitis, Prophylaxy of Post Traumatic Endophthalmitis, Bacterial Endophthalmitis
- Trial name
- NCT00398658
- Testing
- gentamycin and clindamycin
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Endophthalmitis
Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 Months
OZURDEX endophthalmitis is a rare and potentially very serious pathology. Different treatments can be carried out early and change the functional prognosis of the patient.
- Trial name
- NCT06268561
- Testing
- Visual acuity analysis, Intraocular pressure analysis, Analysis of optical coherence tomography (OCT) images
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Conjunctivitis, Iritis
Screening for NEI Clinical Studies
This screening protocol is designed to facilitate patient recruitment to National Eye Institute (NEI) clinical research studies.
- Conditions
- Conjunctivitis, Iritis, Keratitis, Retinitis
- Trial name
- NCT00001734
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- National Eye Institute (NEI)
Endophthalmitis
OTX-14-002: Device Exposure Registry
The objective of the study is to collect post-approval data relative to the incidence of endophthalmitis for cataract surgery patients treated with the FDA-approved ReSure Sealant when used by a broad group of physicians under…
- Trial name
- NCT02309736
- Testing
- ReSure Sealant
- Sponsor
- Ocular Therapeutix, Inc.
Post-operative Endophthalmitis
Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis
One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more…
- Trial name
- Endophtalmitis (NCT01768078)
- Testing
- Intravitreal injection of Betamethasone + antibiotics, Intravitreal injection of antibiotics
- Where
- 6 sites in France
- Volunteers
- 112 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Ophthalmia Neonatorum
Prevalence of Conjunctivitis and Indentification of Risk Factors With and Without Prophylactic Antibiotic Treatment in Neonates
The French guidelines for the use of Rifamycine eye drops in delivery room to prevent neonatal conjunctivitis have been actualized.
- Trial name
- CRY-NOT (NCT03528915)
- Testing
- Rifamycine treatment, whithout Rifamycine treatment
- Where
- France
- Volunteers
- 881 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens