Clinical trials: Endoscopic Therapy
Paediatric Hydrocephalus
Efficacy of Combined Endoscopic Third Ventriculostomy and Choroid Plexus Cauterization in Treatment of Hydrocephalus
Hydrocephalus remains one of the most common conditions encountered in neurosurgery, traditionally managed by ventriculoperitoneal (VP) shunting.
- Trial name
- NCT07735936
- Testing
- Combined endoscopic third ventriculostomy & coroid plexus cauterization
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Pilonidal Sinus
Pilonidal Excision Versus Endoscopic Surgery
Compare clinical outcomes of endoscopic pilonidal sinus treatment (EPSiT) with excision treatment with a randomised clinical trial.
- Trial name
- PEVES (NCT03923621)
- Testing
- EPSiT, Excision
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Helens & Knowsley Teaching Hospitals NHS Trust
Early Gastric Cancer
Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection for Early Gastric Cancer
The purpose of this study is to determine whether Endoscopic Submucosal Dissection combine with Laparoscopic Regional Lymph node Dissection for early gastric cancer can improve Disease-free survival ？
- Trial name
- NCT02325999
- Testing
- ESD AND LRLD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Endoscopic Pilonidal Sinus
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease
Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily…
- Trial name
- NCT04418310
- Testing
- Lay open and curettage, Endoscopic (E.P.Si.T) method
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Endoscopy, Peptic Ulcer
High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic Treatment
The study was designed to evaluate the efficacy an adjuvant use of standard dose or high dose of proton pump inhibitor after combined endoscopic hemostasis therapy.
- Conditions
- Endoscopy, Peptic Ulcer, Bleeding, Proton Pump Inhibitors
- Trial name
- NCT00709046
- Testing
- High dose pantoprazole infusion, Standard dose pantoprazole infusion
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Pain
Effect of Virtual Endoscopy Simulator Training on Real Patient Endoscopy
Trainees (Residents in internal medicine), naive to real patient endoscopy, will be randomized to receive either 3 weeks/2 hours per day of structured training for a total of 20 hours on the virtual endoscopy simulator GI-Mentor…
- Trial name
- endosim (NCT00576043)
- Testing
- Simulator Training
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Vienna
Peptic Ulcer Hemorrhage
Resolution Endoclips Vs Epinephrine Injection and Heater Probe
To compare the efficacy of a novel endoscopic clipping device(Resolution Clip™) and conventional epinephrine injection and heater probe thermocoagulation in control of peptic ulcer bleeding and prevention of recurrent bleeding
- Trial name
- NCT00165009
- Testing
- Resolution clip (endo-clipping device)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Chinese University of Hong Kong
Hydrocephalus in Children
Precision Surgery for Pediatric Hydrocephalus: VPS vs. ETV With ML-Guided Prediction
Study type: Multicenter retrospective cohort study with prospective validation Primary purpose: To determine whether an individualized, imaging-guided treatment algorithm Ventriculoperitoneal shunt (VPS) vs endoscopic third…
- Trial name
- VPS ETV ML (NCT07330206)
- Testing
- MRI-Guided Precision Shunt or ETV Strategy
- Where
- China
- Volunteers
- 800 people
- Sponsor
- West China Hospital
Lumbar Herniated Disc
US-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the feasibility and efficacy of US-MR image fusion-guided percutaneous transforaminal endoscopic discectomy for the treatment of lumbar disc herniation
- Trial name
- NCT03403244
- Testing
- US-MR image fusion-guided PTED, fluoroscopy-guided PTED
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Obese Adolescents, Obesity, Morbid
ESG in Obese Adolescents
The primary goal of this pilot study is to learn if the use of the Apollo Endosurgery ESG System is a safe, well tolerated intervention for weight loss in adolescents with obesity.
- Conditions
- Obese Adolescents, Obesity, Morbid, Obesity/Therapy
- Trial name
- NCT06914765
- Testing
- Endoscopic Sleeve Gastroplasty (ESG) Procedure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Crohn Disease
Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease
Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both.
- Trial name
- CAMEO (NCT05781152)
- Testing
- Anti-TNF therapy
- Where
- 26 sites in United States, Canada
- Volunteers
- 1,270 people
- Sponsor
- Connecticut Children's Medical Center
Early Gastric Cancer
Endoscopic Submucosal Dissection Versus Surgery in the Treatment of Early Gastric Cancer
In this study, patients who are going to undergo endoscopic submucosal dissection (ESD) or surgery for early gastric cancer will be enrolled and divided into ESD group and Surgery group according to the procedure they go through.
- Trial name
- NCT03857737
- Testing
- endoscopic submucosal dissection, Surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Vesico-Ureteral Reflux
Endoscopic Injection of Dextranomer/Hyaluronic Acid Versus Ureteral Reimplantation In Treatment of Vesicoureteral Reflux
In this study, the investigators aim to compare the outcomes of Dextranomer/hyaluronic acid (Dexell®) and extravesical reimplantation (Lich- Gregoir) procedures for primary vesicoureteral reflux (VUR) grades III and IV in…
- Trial name
- NCT04798443
- Testing
- subureteral endoscopic Injection of Dextranomer/Hyaluronic acid (Dexell), open ureteral reimplantation (Lich-Gregoir)
- Volunteers
- 60 people
- Sponsor
- Elsayed Salih
Obesity, Morbid
Aspiration Therapy for Obese Adolescents
Interventional studies devoted to adolescents are relatively rare in the world. This has several reasons. Treatment and research on obesity are centered on advanced forms of obesity in adults, bearing in mind that social and…
- Trial name
- NCT03598920
- Testing
- AsspireAssist, Nutritional consulting
- Where
- 3 sites in Czechia
- Volunteers
- 20 people
- Sponsor
- University Hospital Ostrava
Cervical Preinvasive Disease
Tissue Sparing Therapy of Female Precancerous Genital Lesions With VITOM
Object of the study is the evaluation of the use of a rigid laparoscope for the diagnosis and therapy of lesions of the female genital tract as a substitution or a complementary method to colposcopy with the development of new…
- Trial name
- VITOM (NCT01601769)
- Testing
- Vitom, Colposcopy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Rhinosinusitis With Nasal Polyps
Efficacy of Long-Term Low Dose Macrolide Therapy in Preventing Early Recurrence of Nasal Polyps After Endoscopic Sinus Surgery
This randomized controlled trial evaluated the effectiveness of long-term, low-dose clarithromycin (250 mg/day) in reducing symptoms, improving endoscopic and radiologic scores, and preventing early recurrence of nasal polyps…
- Trial name
- NCT07316959
- Testing
- clarithromycin 250 mg
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Jinnah Medical University
Sedation Complication
Comparison of High-Flow Nasal Cannula Oxygen Application and Classic Nasal Cannula Oxygen Application
Recently, sedation practices have increased for diagnostic and interventional procedures for children in non-operating rooms. On the other hand, the rate of respiratory complications especially in non-operating room sedation…
- Trial name
- NCT04472273
- Testing
- high-flow nasal cannula / classic nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Upper Gastrointestinal Bleeding
Oral vs Intravenous and Proton Pump Inhibitor (PPI）for Peptic Ulcer Bleeding (PUB)
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality. Endoscopic therapy significantly reduces further bleeding, surgery, and mortality in patients with bleeding peptic ulcers and is…
- Trial name
- NCT01123031
- Testing
- lansoprazole, esomeprazole
- Sponsor
- Changhua Christian Hospital
Diabetes Mellitus, Type 2, Obesity
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
To assess whether holding incretin-based therapy before endoscopy reduces the likelihood of clinically relevant Residual Gastric Volume (RGV).
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Gastroparesis
- Trial name
- NCT06533527
- Testing
- GLP-1 medication
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic