Clinical trials: Endothelial Corneal Dystrophy
Keratoconus, Fuchs Dystrophy
Femtolaser Assisted Keratoplasty Versus Conventional Keratoplasty
This pilot study will compare upto 15 patients undergoing femtolaser assisted keratoplasty (using CE[Conformité Européene] approved femtolaser apparatus) with upto 15 patients undergoing conventional keratoplasty with a manual…
- Conditions
- Keratoconus, Fuchs Dystrophy, Corneal Disease
- Trial name
- NCT03619434
- Testing
- Femtosecond Laser, Trephine blade
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Southampton
Corneal Dystrophy
Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal Subjects
The purpose of this study is to compare corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with special reference to glycemic status.
- Trial name
- NCT01084850
- Where
- Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Fuchs Endothelial Corneal Dystrophy, Descemet Membrane Endothelial Keratoplasty (DMEK)
Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)
The goal of this clinical trial is to learn if a longer period of lying on the back after corneal transplant surgery (Descemet Membrane Endothelial Keratoplasty, DMEK) helps the transplant stick better in the eye.
- Trial name
- SUPINE (NCT07373821)
- Testing
- Duration of Supine Positioning
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Heidelberg
Congenital Hereditary Endothelial Dystrophy of Cornea
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops
CHED- Congenital Endothelial Endothelial Dystrophy is a condition that causes corneal cloudiness. Since, currently only surgery is being done to cure this condition, we are taking up the research of using topical eye drops for…
- Trial name
- NCT04843839
- Testing
- Nepafenac 0.1% Oph Susp, Refresh Tears 0.5% Lubricant Eye Drops
- Where
- India
- Volunteers
- 30 people
- Sponsor
- L.V. Prasad Eye Institute
Fuchs' Endothelial Dystrophy, Cataract
Risk Assessment for Progression to DMEK Following Cataract Surgery in Fuchs Endothelial Corneal Dystrophy
Justification. Fuchs' corneal endothelial dystrophy (FECD) is one of the main causes of corneal transplantation. In many cases, the corneal decompensation derived from this dystrophy is triggered as a consequence of cataract…
- Trial name
- NCT04072029
- Testing
- Phacoemulsification with intraocular lens implantation
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Pseudophakic Bullous Keratopathy, Fuchs' Endothelial Dystrophy
Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEK
To evaluate the clinical outcomes (pos toperative best corrected visual acuity, endothelial count) and anatomical results (interface smoothness) of DSAEK with Femto LDV-prepared grafts from the endothelial side.
- Trial name
- NCT06652321
- Testing
- Endothelial Side Up Femtosecond Laser Assisted DSAEK
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Dar El Oyoun Hospital
Fuchs' Endothelial Dystrophy
The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy
The purpose of this study is to gain further insights into the molecular pathogenesis of Fuchs' endothelial corneal dystrophy (FECD), to identify targets for potential specific drug therapy.
- Trial name
- NCT01795001
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 460 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven