Clinical trials: Endothelial Progenitor Cells
Coronary Artery Disease
Deutsches Dual Therapy Stent Register
The DTS.DE registry is an initiative for the collection of high quality process and historical data of implantations with the COMBO Dual Therapy Stent in Germany.
- Trial name
- DTS Register (NCT02102997)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- OrbusNeich
Graft-Versus-Host Disease
Tissue Repair in Stem Cell Transplant Recipients
Primary Objective: 1. To determine whether rhG-CSF treatment will increase the frequency of donor-derived cells contributing to repair of damaged epithelial/endothelial or solid organ-specific tissue caused by graft-versus-host…
- Trial name
- NCT00501228
- Testing
- Filgrastim
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- M.D. Anderson Cancer Center
Coronary Arteriosclerosis
Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease
This study will measure and compare the levels of endothelial progenitor cells (EPCs) in the blood of people with and without risk factors for atherosclerosis (hardening of the arteries) to see if there is a relationship between…
- Trial name
- NCT00013975
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Effect of Nitric Oxide Donor on Endothelial Progenitor Cells in Patients With Coronary Artery Disease
Regular exercise reduces the risk of heart problems, in part because it improves the work of the endothelium (the cells that line blood vessels).
- Trial name
- NCT00090558
- Testing
- nitroglycerin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sinusoidal Obstruction Syndrome
Sinusoidal Obstruction Syndrome for Stem Cell Transplant Patients Biomarker Study
The goal of this is to learn more about stem cell transplant and complications that some people have after their transplants, in particular sinusoidal obstruction syndrome (SOS), also called veno-occlusive disease of the liver.
- Trial name
- SOSBiomarker (NCT03132337)
- Testing
- Serial Blood Draws
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Hematopoietic Stem Cell Transplant (HSCT), Endothelial Injury
Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index
Chemotherapy and radiation used in patients undergoing bone marrow transplant (BMT) disrupts the endothelial lining (a thin layer of cells inside the blood vessels) which is found all throughout the body including the kidney…
- Trial name
- NCT05524246
- Testing
- Pravastatin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myocardial Infarction, Reperfusion Injury
Role of Adiponectin and Endothelial Progenitor Cells in Reperfusion Injury in Patients With Acute Myocardial Infarction
There is experimental evidence that low levels of adiponectin are associated with more reperfusion injury. In addition experimental studies have demonstrated that endothelial progenitor cells may have a favorable effect on…
- Trial name
- R²ACE (NCT01414452)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Universiteit Antwerpen
Coronary Arteriosclerosis
The Effect of Exercise on Stem Cell Mobilization and Heart Function in Patients Undergoing Cardiac Rehabilitation
This study will look at the effect of a cardiac rehabilitation exercise program on release of stem cells from the bone marrow and on heart function.
- Trial name
- NCT00053456
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Vascular Formation
Effect of Regular Exercise on Vascular Function and Cardiovascular Risk in a Sedentary Work Force
This study will evaluate the effects of NHLBI's employee exercise program, Keep the Beat, on blood vessel function. Damage to blood vessels can cause narrowing of the vessels, resulting in reduced blood flow to parts of the body…
- Trial name
- NCT00246883
- Testing
- Exercise
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Atherosclerosis
Endothelial Dysfunction in Obese Children
The purpose of this study is to objectify the effect of diet and exercise on early markers of atherosclerosis in obese children.
- Trial name
- EDOC (NCT01461226)
- Testing
- Exercise training, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 61 people
- Sponsor
- University Hospital, Antwerp
Central Nervous System
Investigating Endothelial Precursor Cells (EPCs)
Recent studies suggest that cells in the bone marrow-endothelial precursor cells (EPCs)-can provide a blood supply to cancerous tumors.
- Trial name
- NCT00067067
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Congenital Disorders of Glycosylation
Role of the Endothelium in Stroke-like Episode Among CDG Patients
The aim of the study is to evaluate the role of the endothelial barrier in the occurrence of stroke-like episode. And to study the protein C system on the surface of the endothelium.
- Trial name
- PECDG (NCT03250728)
- Testing
- Peripheral blood puncture
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
Age and Endothelial Progenitor Cell Mobilization
It is hypothesized that aging is associated with reduced vascular injury-induced endothelial progenitor cell activity, resulting in impaired vascular repair and increased vascular disease.
- Trial name
- AGE-PCI (NCT00585949)
- Testing
- Percutaneous Coronary Angioplasty, Angiography
- Where
- 2 sites in United States
- Volunteers
- 123 people
- Sponsor
- Emory University
Haploidentical Hematopoietic Stem Cell Transplantation
Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation
The aim of the study is to evaluate the efficacy of the prophylactic administration of N-acetyl-L-cysteine (NAC) in acute leukemia patients with complete remission pre- and post-allotransplant on the occurrence of poor graft…
- Trial name
- NCT03236220
- Testing
- N-acetyl-L-cysteine
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Peking University People's Hospital
Placental Transfusion, Stem Cells
Placental Transfusion Methods and Stem Cells
To measure the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells levels, and placental residual volume by delayed cord clamping, umbilical cord milking or immediate cord clamping in newborns at different…
- Trial name
- NCT03983902
- Testing
- Delayed cord clamping, Umbilical cord milking, Immediate cord clamping
- Volunteers
- 96 people
- Sponsor
- Ankara University
Congestive Heart Failure
The Effect of Left Ventricular Filling Pressure on Pulmonary Clearance of Free Radical Loaded White Blood Cells and Platelets in Congestive Heart Failure Patients Before and After Biventricular Pacing
1. To assess whether a correlation exist between the degree of pulmonary clearance of free radical positive white bloodcells and platelets and the degree of pulmonary congestion in congestive heart failure (CHF) patients 2.
- Trial name
- OXIS-PACING (NCT00716885)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Amsterdam UMC, location VUmc
Atypical Hemolytic Uremic Syndrome
Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy
Hemolytic Uremic Syndrome (HUS) is a rare disease characterized by rupture of red blood cells (hemolytic anemia), low platelet count (thrombocytopenia), and thrombotic occlusion of small vessels (thrombotic microangiopathy), with…
- Trial name
- aHUS-iPSC-EC (NCT05805202)
- Testing
- Blood sampling and urine analysis
- Where
- Italy
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Physical Activity, Endothelial Dysfunction
Recreational Physical Activity and Cardiometabolic Profile
The purpose of present study was to investigate the effect of 10 weeks of recreational physical activity program on the irisin levels, progenitor endothelial cells and cardiometabolic profile in healthy children.
- Conditions
- Physical Activity, Endothelial Dysfunction, Metabolic Syndrome x
- Trial name
- NCT02982967
- Testing
- Physical Activity
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo