Clinical trials: Enterocolitis, Necrotizing
Necrotizing Enterocolitis
Administration of Arginine Supplementation in Preterm Infants
Calprotectin is a cytosolic component of neutrophils .Fecal calprotectin(FC) is a useful marker for exacerbation of inflammatory bowel disease in children .FC may be a useful marker for necrotizing enterocolitis (NEC).
- Trial name
- NCT01336998
- Testing
- arginine
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Alexandra Hospital, Athens, Greece
Necrotizing Enterocolitis
Monitoring Necrotizing Enterocolitis in Premature Infants
The investigators are studying a disease called "necrotizing enterocolitis" (or "NEC" for short), which affects premature infants.
- Trial name
- NCT01287559
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Spectros Corporation
Sepsis, Bronchopulmonary Dysplasia
Cysteine Supplementation in Critically Ill Neonates
Critically ill babies less than 1 month of age have deficient amounts of the antioxidant glutathione and a high incidence of disease associated with oxidative injury compared to healthy babies.
- Conditions
- Sepsis, Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Retinopathy of Prematurity
- Trial name
- NCT00254176
- Testing
- Parenteral cysteine-HCl supplementation
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of California, Los Angeles
Necrotizing Enterocolitis, Premature Birth
Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder that primarily affects preterm infants. About 10% of babies less than 32 weeks gestation at birth will develop it.
- Trial name
- NCT00059449
- Where
- 3 sites in United States
- Volunteers
- 372 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Patent Ductus Arteriosus
Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus
The purpose of this study is to examine if a higher dose of indomethacin will increase the rate of ductus arteriosus closure in extremely premature infants without increasing the side effects.
- Trial name
- NCT00187447
- Testing
- indomethacin (two different dosing regimens)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Necrotizing Enterocolitis
Pentoxifylline in the Treatment of NEC in Premature Neonates
Pentoxifylline improves microcirculation and decreases TNF alpha levels associated with sepsis, rendering it of potential therapeutic value in necrotizing enterocolitis in premature neonates.
- Trial name
- NCT00271336
- Testing
- Pentoxifylline
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Necrotizing Enterocolitis, Sepsis
Lactulose Supplementation in Premature Infants
A pilot study to test the safety of use of lactulose in preterm infants and to preliminary assess the hypothesis that lactulose would support the early growth of Lactobacilli in the stools of premature infants and possibly would…
- Trial name
- NCT00616876
- Testing
- Lactulose, Dextrose
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Bnai Zion Medical Center
Necrotizing Enterocolitis
Necrotizing Enterocolitis (NEC) Surgical Database
The general objectives of this protocol are to develop a multi-center prospective data collection process to identify risk factors for progression of Necrotizing Enterocolitis (NEC).
- Trial name
- NCT00120159
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Enterocolitis, Necrotizing
Probiotics Reduce Incidence of Necrotizing Enterocolitis for Very Low Birth Weight Infants
We investigate the efficacy of probiotics in reducing the incidence and severity of necrotizing enterocolitis (NEC) for very low birth weight (VLBW) infants.A prospective, masked, multi-center randomized control trial will be…
- Trial name
- NCT00540033
- Testing
- infloran
- Where
- Taiwan
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Necrotizing Enterocolitis
Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants
The primary purpose of this study is to compare two surgical treatments for perforated necrotizing enterocolitis in very low birth weight babies.
- Trial name
- NCT00252681
- Testing
- laparotomy, primary peritoneal drainage
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Yale University
Necrotizing Enterocolitis, Sepsis
Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
OBJECTIVES: I. Compare the incidence of late onset sepsis and/or necrotizing enterocolitis and duration of hospitalization in low birth weight infants fed with fortified mother's milk supplemented with either fortified…
- Trial name
- NCT00005888
- Testing
- Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)