Clinical trials: Esotropia
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Esotropia
Botulinum Toxin Injection Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia
This is a single-center, prospective, randomized controlled trial evaluating type A botulinum toxin injection and prism therapy for the treatment of small-angle acute acquired concomitant esotropia.
- Trial name
- NCT06714877
- Testing
- prism treatment group, botulinum toxin group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Acquired Esotropia
Botox Instead of Strabismus Surgery (BISS)
The purpose of the study is to evaluate if strabismus can be successfully treated requiring less surgical interventions with a Botox-based treatment regimen compared to a purely surgery based treatment regimen.
- Trial name
- BISS (NCT03459092)
- Testing
- Botulinum toxin type A, Strabismus surgery
- Where
- 8 sites in France, Switzerland
- Volunteers
- 63 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Strabismus
Lateral Rectus Resection Versus Lateral Rectus Plication in Patients With Residual Esotropia
In this study, the surgical outcomes of lateral rectus plication and resection techniques on patients with residual esotropia will be compared.
- Trial name
- NCT04213768
- Testing
- Lateral rectus plication, Lateral rectus Resection
- Where
- 2 sites in Iran
- Volunteers
- 57 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Binocular Vision Disorder, Binocular Eye Movement Disorder
Performance and Safety Evaluation of the S360 Medical Device Software.
The aim of this interventional, cross-sectional study is to evaluate the performance and the safety of the medical device software S360.
- Conditions
- Binocular Vision Disorder, Binocular Eye Movement Disorder, Ocular Motion; Disorder
- Trial name
- ArgoS360 (NCT05522595)
- Testing
- S360
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Sierra Neurovision
Accommodative Esotropia
Under-correction in Refractive Accommodative Esotropia
In most clinics, physicians reduce diopter of hyperopic glasses in older patients with accommodative esotropia. However, there are risks of decompensation in that practice.
- Trial name
- NCT01179711
- Testing
- Glasses prescription
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Strabismus
Bilateral Recession or Unilateral Recession-Resection as Surgery for Infantile Esotropia
Infantile esotropia is corrected in most cases by bilateral recession of the medial rectus muscles (BR) or by unilateral recession of the medial rectus muscle and resection of the lateral rectus muscle (RR).
- Trial name
- NCT00304577
- Testing
- Bilateral recession, Unilateral recession and resection
- Where
- 12 sites in Germany, Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Strabismus, Nystagmus, Congenital
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus.
- Trial name
- NCT04770519
- Testing
- whole genome sequencing or whole exome sequencing
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Infantile Esotropia
Study of Clinical Types and Treatment Outcomes of Pediatric Esotropia in Sohag University Hospital
Strabismus (or squint) is defined as the presence of misalignment between the visual axes of the 2 eyes presenting with deviation of the eyes.
- Trial name
- NCT06221098
- Testing
- bilateral medial rectus recession
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Myopia, Strabismus
A Trial of Bifocals in Myopic Children With Esophoria
To test the hypothesis that correction with bifocal spectacle lenses rather than single-vision lenses will slow the progression of myopia in children with near-point esophoria.
- Conditions
- Myopia, Strabismus, Esophoria
- Trial name
- NCT00000128
- Testing
- Bifocal Spectacle Lenses
- Sponsor
- National Eye Institute (NEI)
Cycloplegia, Refractive Errors
Cycloplegic Refraction in Pediatric Patients With Esotropia
The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations with esotropia.
- Conditions
- Cycloplegia, Refractive Errors, Esotropia, Vision Disorders
- Trial name
- NCT06077682
- Testing
- Cyclopentolate, Tropicamide
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Islamic Hospital, Jordan
Esotropia
A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD
Childhood esotropia (ET) is a common cause of visual disability, and its early management is critical for optimal visual and developmental outcomes.
- Trial name
- ETS4 (NCT07470164)
- Testing
- Botulinum toxin A, bilateral medial rectus recession
- Volunteers
- 244 people
- Sponsor
- Jaeb Center for Health Research
Partially Accommodative Esotropia
Augmented Medial Rectus Muscle Recession Versus Posterior Scleral Fixation in Partially Accommodative Esotropia
Prospective randomized interventional comparative study
- Trial name
- NCT02413463
- Testing
- augmented recession, Faden
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Congenital Esotropia
An Observational Cohort Study to Explore the Clinical Outcome of Congenital Strabismmus Based on Etiology and Timing of Surgery
Through high-throughput sequencing and genotype/clinical phenotype/image phenotype analysis, this study will detect and find the clinical characteristics, genetic mode and gene diagnosis of children with congenital strabismus and…
- Trial name
- strabismus (NCT06614335)
- Testing
- After 6 months of observation, there was still a residual inclination of more than 15 prism degrees which needed to be corrected by a second operation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qiyu Bo
Myopia, Esophoria
Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
The purpose of this study is to determine whether bifocal soft contact lenses are effective in controlling the progression of myopia in children and adolescents that exhibit a tendency to excessively cross their eyes while…
- Conditions
- Myopia, Esophoria, Fixation Disparity
- Trial name
- NCT00214487
- Testing
- Bifocal Contact Lenses
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Esotropia
Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin
To investigate long-term treatment outcomes of patients receiving botulinum toxin A therapy for infantile and acquired esotropia.
- Trial name
- NCT00746304
- Where
- Taiwan
- Volunteers
- 164 people
- Sponsor
- National Taiwan University Hospital
Esotropia
Congenital Esotropia Observational Study (CEOS)
To observe the early course of congenital esotropia, a form of childhood strabismus. This will determine the probability of spontaneous resolution.
- Trial name
- NCT00000163
- Sponsor
- National Eye Institute (NEI)
Refractive Errors, Esotropia
Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and Amblyopia
To investigate changes in refractive errors and evaluate clinical outcomes of strabismus surgery in patients with both amblyopia and partially refractive esotropia (PAET).Amblyopic patients with PAET were enrolled.
- Conditions
- Refractive Errors, Esotropia, Amblyopia Strabismic
- Trial name
- NCT04429659
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sakarya University
V Pattern Esotropia, Monocular Exotropia With V Pattern
Correction of V-pattern Strabismus by Graded Recession of Inferior Oblique Muscle .
V pattern strabismus is the commonest of alphabet pattern. Its identification is essential to plan a proper surgical management. Graded recession is a very logical approach to treat inferior oblique overaction (IOOA).
- Trial name
- Pattern (NCT05786053)
- Testing
- graded recession of inferior oblique muscle
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University