Clinical trials: Excavatum, Pectus
Funnel Chest
Cardiorespiratory Assessment and Quality of Life After Surgical Correction of Congenital Wall Malformations
The main objective of this study is to characterize the cardiorespiratory functional gain in patients with pectus excavatum following corrective surgery.
- Trial name
- HeartSoar (NCT03770390)
- Testing
- Surgical correction of pectus excavatum
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Montpellier
Pectus Excavatum
Comparative Analysis Of Modified Vs. Classical Nuss Technique In The Surgical Correction Of Pectus Excavatum "
Although the NUSS technique has become the standard minimally invasive procedure for correcting this deformity, there is a lack of comparative data between the classic and modified NUSS techniques.
- Trial name
- PE (NCT07312448)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Pectus Excavatum
Pain, Exercise and Psychological Well-being in Pectus Excavatum
Recovery following major surgical procedures can be influenced by both physical (optimization of cardiopulmonary function, pain control, activity) and psychological factors.
- Trial name
- PEP (NCT02337621)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Phoenix Children's Hospital
Funnel Chest
Evaluation of Chest Wall Motility After MIRPE
Pectus excavatum (PE) is the most common congenital deformity of the chest wall and surgical treatment using the minimally invasive technique (MIRPE) is consolidating as the choice to perform PE correction.
- Trial name
- NCT05124626
- Testing
- MIRPE with two bars, MIRPE with one bar
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum
Non-invasive Negative Pressure Treatment for Pectus Excavatum
The purpose of this study is to determine whether the non-invasive negative pressure treatment with the use of the device Vacuum Bellfor is effective for the pectus excavatum treatment
- Trial name
- NCT01816373
- Testing
- Vacuum Bell
- Where
- 2 sites in Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pectus Excavatum
Field-test and Psychometric Validation of the Pectus Excavatum Evaluation Questionnaire in the Dutch Pectus Excavatum Population
A questionnaire that can measure disease severity from the patients perspective in patients with pectus excavatum already exists in English (Pectus Excavatum Evaluation Questionnaire; PEEQ).
- Trial name
- TRANSLATE (NCT06918392)
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Erik de Loos
Pectus Excavatum, Pectus Excavatum Deformity
The Effects of Schroth Based Exercise Therapy in Adolescents with Pectus Excavatum
Research on exercise methods for pectus excavatum (PE) is limited, highlighting the need for further studies. This study investigated the effects of Schroth-based exercise therapy combined with vacuum treatment in 35 adolescents…
- Conditions
- Pectus Excavatum, Pectus Excavatum Deformity, Funnel Chest, Chest Deformities
- Trial name
- NCT06763406
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Hacettepe University
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Funnel Chest, Excavatum, Pectus
Cryoanalgesia Aplication Time Optimization During Nuss Procedure
This study compared standard therapy (multimodal analgesia with 2 minutes cryoanalgesia) versus a novel approach (multimodal analgesia with 1 minute cryoanalgesia) in subject undergoing minimal invasive modyfied Nuss procedure…
- Trial name
- NCT05831137
- Testing
- shorter cryoanalgesia
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Pectus Excavatum, Pain, Postoperative
Sub-Paraspinal Block in Nuss Patients. A Pilot Project
The purpose of this pilot study was to evaluate effectiveness of a novel regional anesthesia technique developed at the investigators institution, as part of a quality improvement initiative, to assist with multilevel thoracic…
- Trial name
- NCT02169297
- Testing
- Ultrasound-guided Sub-Paraspinal Block, PCA only
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Pectus Excavatum
Pectus Excavatum Camouflage (IT)
The clinical study evaluates the use of a custom-made medical-grade polycaprolactone-PCL Pectus scaffold implantation with Autologous Fat Grafting for pectus excavatum camouflage (IT).
- Trial name
- NCT05634070
- Testing
- PCL Pectus scaffold implantation and autologous fat grafting
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- BellaSeno GmbH
Pectus Excavatum, Pain, Postoperative
Pectus ESC Outcomes and Comparative Effectiveness Study
Investigators hypothesize that Erector spinae catheter pain management protocol would allow patients to have earlier and more effective rehabilitation with decreased length of hospital stay.
- Trial name
- PectusESC (NCT05063695)
- Testing
- Multimodal Erector spinae catheter protocol
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pectus Excavatum
Quantifying Changes in the Thoracic Wall After Nuss Bar Removal in Pectus Excavatum Patients Using 3D Imaging
Pectus excavatum (funnel chest) is the most common congenital anterior thoracic wall deformity. It can be associated not only with cosmetic concerns but also with psychosocial and limiting somatic complaints.
- Trial name
- CHEST (NCT07498699)
- Where
- Netherlands
- Volunteers
- 69 people
- Sponsor
- Erik de Loos
Funnel Chest, Pectus Excavatum
Intraoperative Cryoanalgesia Versus Thoracic Epidural Block in MIRPE (Minimally Invasive Repair of Pectus Excavatum)
The main objective of this study is to compare epidural blockade with cryoanalgesia of the intercostal nerves as an analgesic method in the postoperative period of minimally invasive repair of pectus excavatum (MIRPE).
- Conditions
- Funnel Chest, Pectus Excavatum, Postoperative Pain After Video Assisted Thoracic Surgery, Postoperative Pain
- Trial name
- FROZEN MIRPE (NCT07431632)
- Testing
- Cryotherapy, Epidural
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Pectus Excavatum, Funnel Chest
Cryoanalgesia vs. Epidural in the Nuss Procedure
The purpose of this study is to determine whether cryoanalgesia provides better pain control for minimally invasive pectus excavatum repair (the Nuss procedure) than thoracic epidural.
- Trial name
- NCT02721017
- Testing
- Cryoanalgesia, Thoracic epidural (ropivicaine, fentanyl)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Pectus Excavatum
Investigation of the Effectiveness of Telerehabilitation Training in Pectus Excavatum Deformity
The aim of this study is to investigate the effectiveness of telerehabilitation-based exercise training in addition to Vacuum Bell therapy on physical fitness, respiratory functions, posture and psychosocial factors in boys aged…
- Trial name
- NCT06635083
- Testing
- Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Eastern Mediterranean University
Pectus Excavatum
Effects of Exercise Therapy on Pectus Excavatum
Pectus excavatum (PE); It is an anterior chest wall deformity, characterized by varying degrees of depression of the sternum and costal cartilage, usually occurring at birth or in the first year of life.
- Trial name
- NCT04167865
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Acibadem University
Pectus Excavatum, Funnel Chest
Optical Surface Imaging Versus Conventional Photography as a Tool to Document the Surface Geometry of Pectus Excavatum
Pectus excavatum is the most common congenital anterior chest wall deformity, known to occur in 1:400 of new-borns. Complaints may be of cosmetic nature or as a consequence of (cardio)pulmonary impairment.
- Trial name
- NCT04185870
- Testing
- 3D scan, Standard photography
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen