Clinical trials: Executive Function Disorders
Executive Function Deficits (EFD)
Unstuck-Early Childhood Effectiveness & Implementation Trial
The goal of this clinical trial is to learn if a new school-based, Tier 2 (selective) cognitive-behavioral intervention called Unstuck and On Target for Early Childhood (Unstuck-EC) can treat executive function deficits in young…
- Trial name
- NCT07832344
- Testing
- Unstuck and On Target for Early Childhood
- Volunteers
- 90 people
- Sponsor
- Children's National Research Institute
Attention Deficit Hyperactivity Disorder
Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD
This study looks to examine whether or not INTUNIV extended release can help children aged 6-12 years diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) in improving Executive Function when added to their usual care…
- Trial name
- NCT01985581
- Testing
- Guanfacine extended release, Stimulant therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- JPM van Stralen Medicine Professional
Autism Spectrum Disorder
Activities of Daily Living Participation Characteristics Among School-Aged Children With Autism Spectrum Disorder
This study aimed to investigate the performance of activities of daily living (ADL) among 53 children ages 6-10 years: 17 with high-severity ASD (HS-ASD), 16 with low-severity ASD (LS-ASD), and 20 controls with typical…
- Trial name
- NCT05186103
- Testing
- observation
- Where
- Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sara Rosenblum
Autism Spectrum Disorder, Executive Dysfunction
Non-invasive Brain Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Conditions
- Autism Spectrum Disorder, Executive Dysfunction, Child Autism
- Trial name
- NCT05105126
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Teaching Academic Success Skills to Students With Autism Spectrum Disorders in Clinical Setting
The goal of the study is to develop an academic EF intervention, Teaching Academic Skills to Kids (TASK), for high functioning (i.e., IQ score ≥80) middle-school youth with ASD and EF deficits.
- Trial name
- TASK-R21 (NCT03606343)
- Testing
- Teaching Academic Skills to Kids
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention Deficit Hyperactivity Disorder
Investigating the Effects of the Temporal Adaptation Approach in Children With ADHD
This study investigates the impact of temporal adaptation interventions on children with Attention Deficit Hyperactivity Disorder (ADHD), focusing on activity self-efficacy, time perception, daily activity routines, and executive…
- Trial name
- NCT06770725
- Testing
- Temporal Adaptation Intervention, Conventional Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Epilepsy
Web-based Intervention to Improve Executive Functioning in Teens With Epilepsy (Epilepsy Journey)
The purpose of this study is to establish the feasibility, accessibility, acceptability, and preliminary efficacy of an individually-tailored intervention to improve EF in adolescents with epilepsy (EFI-E).
- Trial name
- NCT02925663
- Testing
- EFI-E
- Volunteers
- 32 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
High School SUCCESS: Vocational Soft Skills Program for Transition-Age ASD Youth
By utilizing community-based participatory research methods, this research was conducted in collaboration with the community through our partnership of researchers, educators, providers and consumers (Active Collaborative Hub for…
- Trial name
- TAY SUCCESS (NCT04953793)
- Testing
- TAY SUCCESS, Usual Care
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Rady Children's Hospital, San Diego
Heart Defect, Congenital, Executive Dysfunction
Executive Function Intervention for Children With Complex Congenital Heart Disease
Children with complex congenital heart disease (cCHD) nowadays survive thanks to medical advances into their teenage years and adulthood. However, many of them have difficulties with so-called executive functions.
- Trial name
- E-Fit Heart (NCT07692958)
- Testing
- E-Fit Intervention
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Bea Latal
Acquired Brain Injury
Implementation of a HABIT-ILE Intervention at William Lennox Neurological Hospital (NeuREHA)
Using a randomized controlled trial design, in an hospital environment, possible changes induced by the "Hand-arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)" treatment program will be investigated in…
- Trial name
- NeuREHA (NCT05900778)
- Testing
- HABIT-ILE, Conventional intervention
- Where
- 3 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Université Catholique de Louvain
Pediatric Obesity, Binge-Eating Disorder
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and…
- Trial name
- NCT04701671
- Testing
- Observational (not including MRI scanning), Observational (including MRI scanning)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Balance and Executive Functions in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy commonly experience difficulties with balance and may also have challenges involving attention, working memory, cognitive flexibility, and inhibitory control.
- Trial name
- NCT07829770
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Attention-Deficit/Hyperactivity Disorder (ADHD)
Investigation of the Association of Multimodal Neuroimaging and Peripheral Biomarkers With Executive Functions and Emotional Regulation in Adolescents With Attention-Deficit/Hyperactivity Disorder
The purpose of this observational study is to investigate the relationships among resting-state brain connectivity, peripheral blood biomarkers, executive functions, and emotional regulation in adolescents with…
- Trial name
- NCT07800117
- Testing
- No Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Attention Deficit Hyperactivity Disorder
Cognitive-Motor Rehabilitation, Stimulant Drugs, and Active Control in the Treatment of ADHD
The investigators administered a randomized controlled trial (RCT) through random assignment of children with ADHD into three different groups to compare the effects of cognitive-motor rehabilitation, immediate release…
- Trial name
- ADHD (NCT02780102)
- Testing
- Cognitive-Motor Rehabilitation, Ritalin, Active Control
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Allameh Tabatabai University
Traumatic Brain Injury
VR-based EF Rehabilitation for Pediatric TBI
Childhood traumatic brain injury (TBI) poses significant impairment in children's executive functions (EFs) for moderate to severe injuries, yet interventions specifically designed for children's EF rehabilitation post-TBI and…
- Trial name
- NCT03611062
- Testing
- VR Executive Functions Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Massachusetts, Lowell
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Hyperglycemia, Type 1 Diabetes Mellitus
The Influence of Acute Hyperglycaemia on Brain in T1D
The study is going to include 20 adolescents, 5-10 years after onset of T1D, aged 12-20 years, on insulin pump. The participants are going to have MRI of the head in euglycaemic and hyperglycaemic state.
- Trial name
- NCT03188757
- Testing
- hyperglycaemic clamp
- Where
- Slovenia
- Volunteers
- 20 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Autism Spectrum Disorder
Exercise Interventions for Children With Autism Spectrum Disorder
The purpose of this clinical trial is to find out whether exergame and aerobic exercise can improve sleep, movement skills, thinking abilities, and brain activity in children with autism spectrum disorder (ASD).
- Trial name
- NCT07789457
- Testing
- Exergaming, Aerobic exercise, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder
Skills Training for Adolescents With ADHD
The proposed study will be an initial test of a cognitive-behavioral intervention for adolescents with ADHD who are receiving medication treatment.
- Trial name
- NCT01019252
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Virtual Reality Supported Rehabilitation for Children's Executive and Metaphonological Skills
Executive functions and metaphonological skills are closely interconnected in supporting language development and learning processes.Investigating this relationship could offer new insights into how executive and metaphonological…
- Trial name
- NCT07426289
- Testing
- vrrs, Treatment as usual
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo