Clinical trials: Executive Function Disorders
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Drepanocytosis, Chronic Neurological Deficiency
Transfusion Exchanges and Cognition in Sickle Cell Disease
DREPA-COG is an observational study evaluating the effect of exchange transfusions on cognitive function in adults with severe sickle cell disease (SS or Sβ0).
- Trial name
- DREPA-COG (NCT07168447)
- Where
- 6 sites in France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier St Anne
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Bipolar Disorder
The Effect of Intranasal Insulin on Neurocognitive Function in Euthymic Patients With Bipolar Disorder
It is hypothesized that the intranasal administration of insulin will enhance hippocampal-dependent neurocognitive performance in euthymic patients with bipolar I or II disorder.
- Trial name
- NCT00314314
- Testing
- Intranasal Insulin, Diluent
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Parkinson's Disease
Gait Characteristics and Cognitive Evolution in Parkinson Disease
Parkinson's disease (PD) is a chronic progressive nervous system disease with gradual motor impairment. Cognitive dysfunction is common in PD, even in the early stages, and it is characterized by impairments in executive…
- Trial name
- GECO-PD (NCT04297800)
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Preterm Infant
Executive Functions and Preterm Children in 3 to 4 Year Old
Preterm children have a high risk for neurodevelopmental impairments. The impact on motor functions and neurosensory functions is demonstrated but the incidenceof executive functions is not described for preterm infants.
- Trial name
- NCT03700463
- Testing
- BRIEF parental survey
- Where
- France
- Volunteers
- 356 people
- Sponsor
- Nantes University Hospital
Schizophrenia
Emotional and Cognitive Abilites of Schizophrenia Patients at Various Time Points
Longitudinal investigation of cognitive, emotional and illness awareness of schizophrenia outpatients (Shalvata Mental Health Center).
- Trial name
- NCT00518999
- Volunteers
- 120 people
- Sponsor
- Shalvata Mental Health Center
Behavioral and Emotional Disorder With Onset in Childhood
Emotional Dysregulation and Other Psychopathological Dimensions in Clinical Preschoolers
The purpose of the study is to investigate the emotional-behavioral dysregulation and its possible correlation with the main demographic and psychopathological variables in a sample of preschool children with internalizing and…
- Trial name
- NCT07805668
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Fondazione Stella Maris
Mild Cognitive Impairment (MCI)
Creative Dance-Supported CO-OP Approach in Older Adults With Mild Cognitive Impairment
The goal of this clinical trial is to evaluate if the CO-OP (Cognitive Orientation to daily Occupational Performance) approach, supported by creative dance, can improve cognitive functions in older adults with mild cognitive…
- Trial name
- COOP-DANCE (NCT06644690)
- Testing
- CO-OP with Creative Dance, CO-OP Only
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Çankırı Karatekin University
Traumatic Brain Injury, Cerebrovascular Accident (CVA)
Managing Dysexecutive Syndrome (DS): CIHR 2011-2014
Successful community participation following acquired brain injury (ABI) continues to be an elusive goal for patients, clinicians and researchers.
- Conditions
- Traumatic Brain Injury, Cerebrovascular Accident (CVA), Acquired Brain Injury
- Trial name
- NCT01414348
- Testing
- Conventional rehabilitation., Novel rehabilitation approach
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Baycrest
Parkinson's Disease
Executive, Activities of Daily Living, and Cholinergic Functions in Parkinson's Disease
This research study will evaluate functions of memory, thinking, behavior, and daily life activities and how these relate to the measurement of certain chemicals (acetylcholine and dopamine) in the brain using an imaging…
- Trial name
- NCT00737217
- Testing
- Behavioral assessment/questionnaire
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Aging, Alzheimer's Disease (AD)
Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study
Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk.
- Trial name
- MUST (NCT06995638)
- Testing
- Web-based Cognitive Training (with strategy), Web-based Cognitive Training (without strategy)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Attention Deficit Hyperactivity Disorder, Executive Dysfunction
Executive Control Training for Adolescents With ADHD: A Randomized Controlled Effectiveness Trial
The goal of this clinical trial is to evaluate an evidence-based, non-pharmacological treatment alternative: Goal Management Training (GMT) for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- ADHD Effect (NCT05874791)
- Testing
- Goal Management training
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Cognitive Orientation, Executive Dysfunction
THE EFFECT OF THE COGNITIVE ORIENTATION TO DAILY OCCUPATIONAL PERFORMANCE (CO-OP) APPROACH IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER ON MOTOR PERFORMANCE AND EXECUTIVE FUNCTIONS
Attention deficit and hyperactivity disorder (ADHD) is a behavioural and neurodevelopmental disorder that can affect behavioural, emotional, academic, social, and cognitive functions and is not age-appropriate.
- Conditions
- Cognitive Orientation, Executive Dysfunction, Motor Activity
- Trial name
- NCT05125120
- Testing
- COGNİTİVE ORİENTATİTON DAİLY OCCUPATİONAL PERFORMANCE APPROACH
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Early Onset Parkinson Disease, Early Stage Parkinson Disease
Dual-task Performance in Young-onset PD
This study aimed to investigate the effects of Game based dual-task training with treadmill on executive function and dual-task performance in individuals with early-onset PD and discuss the correlation between the change values…
- Trial name
- NCT04033393
- Testing
- Game based dual-task training, Treadmill training
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Traumatic Brain Injury
Virtual Reality in Rehabilitation of Executive Functions in Children With Mild or Moderate Traumatic Brain Injury
Traumatic brain injury (TBI) causes lifelong disability. Children with TBI often have difficulties in attention regulation and executive functions affecting their daily living.
- Trial name
- VREALFUN-TBI (NCT06127459)
- Testing
- Parental Guidance, Virtual Reality Game
- Where
- Finland
- Volunteers
- 44 people
- Sponsor
- Merja Nikula
Executive Dysfunction, ASD
Effect of rTMS on the Abnormal Executive Function of ASD Children
In this study, the investigators will explore the effects of repetitive transcranial magnetic stimulation (rTMS) on executive function deficits in high function autism spectrum disorder.
- Trial name
- NCT04237870
- Testing
- Active cTBS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Obesity, Weight Loss
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted…
- Conditions
- Obesity, Weight Loss, Weight Management, Dietary Intervention
- Trial name
- NCT06809166
- Testing
- Contrave, Diet Program
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Mild Cognitive Impairment
DIetary Supplements, Executive funcTions and Vitamin D (DIET-D)
The purpose of this study is to compare the effect after 12 weeks of the oral intake of Lecitone®Se + 200UI/day of D3 vitamin with the effect of a placebo on changes in cognitive performance in Trial Making Test score part B…
- Trial name
- DIET-D (NCT01708005)
- Testing
- Lecitone®Se-Vitamin D3
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Angers