Clinical trials: Executive Function Disorders
Neurological Diseases or Conditions
Rehabilitation Through the Italian Version of the Teen Online Problem-Solving (TOPS) Program
The study aims at evaluating the feasibility and the efficacy of the Teen On-line Problem Solving program (TOPS) in improving executive functioning and behavior problems in adolescents with neurological condition aged 11-19…
- Trial name
- TOPS (NCT05169788)
- Testing
- Teen On-line Problem Solving
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit Hyperactivity Disorder
Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder
The present project is to identify the relationship between ADHD and the metabolites of tryptophan.
- Trial name
- NCT03901859
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Asthma
Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social…
- Conditions
- Autism Spectrum Disorder, Asthma, Executive Dysfunction, Emotional Problem
- Trial name
- NCT03269110
- Testing
- SRS 2, CBCL, BRIEF-P
- Where
- 58 sites in Australia, Canada and 2 more
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Family Health, Child Health
Healthy Children 2021 Study in Childcare Centers
In Portugal, 17.3% of children under 10 years old are overweight and 7.7% are obese. Research has shown the implementation of healthy lifestyle promotion programs and obesity prevention, however "best practices" are far from…
- Conditions
- Family Health, Child Health, Sleep, Child
- Trial name
- HC2021 (NCT04082247)
- Testing
- The education and training of early childhood educators and their intervention on children
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Minho
Attention Deficit Hyperactivity Disorder (ADHD), Brain Computer Interface
A Brain-Computer Interface-Based Attention Training Program Compared With Methylphenidate and Citicoline
The goal of this observational study is to learn whether a brain-computer interface (BCI)-based attention training program, used alone or together with medication, can improve attention, executive functioning, and emotional…
- Trial name
- Brain-Computer (NCT07333339)
- Testing
- Brain-Computer Interface-Based Attention Training
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Uludag University
Executive Function (Cognition), Soccer Training
Cognitive-Integrated Soccer Training and Performance
This study will examine whether an 8-week soccer-specific cognitive-motor training program can improve executive functions, decision-making, and soccer skill performance in youth soccer players.
- Conditions
- Executive Function (Cognition), Soccer Training, Performance, Motor Development
- Trial name
- NCT07284940
- Testing
- Cognitively Engaging Soccer Practice, Conventional Soccer Practice
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Fan Mao
Pediatric Obesity, Executive Function
Acceptance-based Care for Child Eating and Physical Activity Treatment
The purpose of this study is to develop and pilot test a new type of patient-centered, family-based treatment for children aged 8-12 with obesity and their caregivers.
- Conditions
- Pediatric Obesity, Executive Function, Self-Regulation
- Trial name
- ACCEPT (NCT03368716)
- Testing
- Acceptance-based Behavioral Treatment (ABBT)
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Attention Deficit Hyperactivity Disorder (ADHD), Attention Deficit Disorder (ADD)
Home-Based tDCS in Children With ADHD: A Randomized, Sham-Controlled tDCS and fNIRS Study
The purpose of this study is to investigate the efficacy of twenty daily sessions of home-based tDCS over the left DLPFC, right IFG on attention and response inhibition in children with ADHD.
- Trial name
- NCT04634006
- Testing
- Home-based transcranial direct current (tDCS) device
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- Onze Lieve Vrouw Hospital
Congenital Heart Disease, Neurodevelopment
Improving Neurodevelopment in Adolescents With Congenital Heart Disease
Executive dysfunction can profoundly impact all dimensions of a child's development. Impairments in executive function are a central component of the neurodevelopmental phenotype associated with CHD, and manifest as behavioral…
- Conditions
- Congenital Heart Disease, Neurodevelopment, Executive Function, Working Memory Training
- Trial name
- NCT02759263
- Testing
- Cogmed Working Memory Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Phenylketonuria
Phase 2 Study of Glycomacropeptide Versus Amino Acid Diet for Management of Phenylketonuria
For individuals with Phenylketonuria (PKU), the investigators hypothesize that glycomacropeptide will provide an acceptable form of low-phenylalanine dietary protein that will improve dietary compliance, blood phenylalanine…
- Trial name
- PKU (NCT01428258)
- Testing
- GMP Diet/GMP Medical Foods, AA Diet/AA Medical Foods
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder
Examining the Efficacy of the T-STEP
The objective of this study is to evaluate the TEACCH School Transition to Employment and Post-Secondary Education (T-STEP) Program.
- Trial name
- NCT04612231
- Testing
- TEACCH School Transition to Employment and Postsecondary Education (T-STEP), Counseling Services Alone
- Where
- 5 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Hyperactivity Disorder (ADHD)
Home-Based Executive Function Training Intervention For Attention-Deficit/ Hyperactivity Disorder-prone Children
This study aims to investigate the effectiveness of a home-based executive function training Intervention on children's ADHD symptoms, executive function and parents' parenting stress.
- Trial name
- NCT06950866
- Testing
- Home-based executive function training therapy
- Volunteers
- 100 people
- Sponsor
- Wuhan Mental Health Centre
Epilepsy in Children, Executive Dysfunction
Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy
The goal of this multi-site clinical trial is to determine the effectiveness of two components of a web-based intervention (Epilepsy Journey) to improve executive functioning in adolescents with epilepsy.
- Trial name
- NCT06608966
- Testing
- Epilepsy Journey web-based modules, Telehealth with a therapist
- Where
- 3 sites in United States
- Volunteers
- 310 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ADHD
Effect of Risperidone on Cognitive Functions in Adolescents With ADHD and Behavioral Disturbances
Introduction: The use of low dose risperidone and other antipsychotic drugs off-label as augmentation treatment for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) and Disruptive Behavioral Disorder (DBD) has…
- Trial name
- NCT02906501
- Testing
- The Penn Web-Based Computerized Neurocognitive Battery, The Iowa Gambling Test (IGT)
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Shalvata Mental Health Center
ADHD
Experimental Research on the Training of Executive Functions Through the APP "The Apollo & Rosetta Adventures" (E-FAR) in Children with ADHD (8-13 Yrs)
ADHD is one of the most prevalent neurodevelopmental disorders, with a strong impact on general functioning and in daily life. Executive Functions play an important role on this disorder, and numerous treatments have been…
- Trial name
- E-FAR (NCT06881719)
- Testing
- The Adventures of Apollo & Rosetta
- Where
- 2 sites in Italy
- Volunteers
- 35 people
- Sponsor
- University of Milano Bicocca
Obesity
The Influence of Obesity on Level of Depression and Cognitive and Executive Functions
The proposed study is a randomized, open, comparative research involving an intervention group and two control groups. The aims of the study are: 1.To compare levels of depression in female adolescents with obesity and a control…
- Trial name
- NCT03087994
- Testing
- Nutritional guidance intervention
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Healthy
Executive Training and Brain in Adolescent
The purpose of this study is to investigate the cognitive and brain effects of inhibitory control (IC) training at adolescence.
- Trial name
- APEX-ADO (NCT03084848)
- Testing
- Training
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder
Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
The aim of the study is to determine the effects of usage of augmented reality for Restricted and repetitive behavior and executive function of children with autism spectrum disorder
- Trial name
- NCT05962047
- Testing
- Games of WonderTree Augmented Reality, Traditional therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Attention Deficit/Hyperactivity Disorder
Structural and Functional Connectivity of Frontostriatal and Frontoparietal Networks as Endophenotypes of ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, clinically and genetically heterogeneous neuropsychiatric disorder with lifelong executive dysfunctions.
- Trial name
- NCT01682915
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- National Taiwan University Hospital
Intracranial Central Nervous System Disorder, Mental Disorder
Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
This study will examine the underlying mental processes that determine how people understand social behavior, remember information, and think.
- Conditions
- Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
- Trial name
- NCT00024908
- Where
- United States
- Volunteers
- 949 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)