Clinical trials: Extremity
Club Foot
Midfoot Osteotomy Versus 8-Plate Epiphysiodesis for Residual Metatarsal Adductus
Epiphysiodesis
- Trial name
- NCT07466043
- Testing
- Midfoot Osteotomy, 8-Plate Epiphysiodesis
- Volunteers
- 40 people
- Sponsor
- Assiut University
Soft Tissue Defects, Perforator Flap
Perforator Pedicled V-Y Advanced Flaps for Coverage in the Lower Limbs
Repair of soft tissue defects with hardware exposing in the lower limbs was considered as a severe challenge for plastic surgeons in reconstructive surgery.
- Trial name
- NCT06885450
- Testing
- Perforator Pedicled Flaps
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Development Delay
The Balance Influence of Shoe Inserts on Motor Development Delayed Children
Flatfoot, one of the most common foot problems experienced by preschool-aged children, characterized by the collapse of the foot's medial longitudinal arch.
- Trial name
- NCT02644317
- Testing
- Modified shoe inserts
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chung Shan Medical University
Cerebral Palsy
Effect of Kinesio-taping of Lower Limbs
The goal of this clinical trail is to test if kinesio-taping on lower limbs has an effect on balance and gait in children with diplegic cerebral palsy.
- Trial name
- NCT06326164
- Testing
- kinesio-taping., A designed physiotherapy program.
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Stroke
Effects of CHRIST on Upper Limb Function in Children With Pediatric Stroke
Pediatric stroke poses significant challenges due to its impact on a child's developing brain. Both ischemic and hemorrhagic strokes in children can result in long-term motor, sensory, and cognitive impairments, particularly…
- Trial name
- NCT07441057
- Testing
- CHRIST
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Clubfoot
Gait Analysis in Children With Clubfoot Treated With Tibialis Anterior Tendon Transfer
Patients with clubfoot treated with the Ponseti method and undergoing Tibialis Anterior tendon transfer from a prospective database are evaluated using gait analysis including the Oxford foot model and compared to a group of…
- Trial name
- NCT03953430
- Testing
- Gait analysis
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Orthopedic Hospital Vienna Speising
Phantom Limb Pain, Complex Regional Pain Syndromes
A Clinical Trial of Mirror Treatment for Phantom Pain
A randomized controlled clinical to examine the effect of mirror therapy on phantom pain and residual limb pain in patients with traumatic transtibial amputations in Cambodia.
- Trial name
- NCT02912975
- Testing
- Mirror treatment, Tactile treatment
- Where
- Cambodia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Trauma Care Foundation, Norway
Clubfeet, Adolescent Idiopathic Scoliosis
Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet
While studies have shown that better outcomes are associated with brace wear compliance in the scoliosis and clubfoot populations, compliance rates are still poor.
- Trial name
- NCT02755766
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Shriners Hospitals for Children
Anterior Cruciate Ligament Repair
Minimizing Tourniquet Pressures in Paediatric Orthopaedic Knee Surgery
Tourniquet cuffs are routinely used to stop blood flow in patients' arms or legs during surgery. This allows surgeons to better visualize anatomical structures during the procedure.
- Trial name
- NCT00439153
- Testing
- Tourniquet instrument capable of measuring LOP in combination with tourniquet cuffs
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of British Columbia
Cerebral Palsy Spastic Hemiplegic
Effectiveness of Universal Exercise Unit Exercise on Upper Limb Strength Using Biodex Isokinetic
The aim of the study is to determine the role of designed program in the universal exercise unit on upper limb function and strength in children with spastic hemiplegia.
- Trial name
- UEU/CP (NCT07233031)
- Testing
- Experimental, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Unilateral Cerebral Palsy
Validation of AI for Personalized Assessment and Rehabilitation of Upper Limb in Children With Unilateral Cerebral Palsy
Unilateral Cerebral palsy (UCP) is the most common neurological chronic disease in childhood with a significant burden on children, their families and health care system.
- Trial name
- AInCP (NCT06073522)
- Testing
- Artificial Intelligence for combining multi-domain data acquisition
- Where
- 2 sites in Italy, Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Limb-girdle Muscular Dystrophy
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4
This is a multicenter, global study of the effects of a single systemic dose of SRP-9003 on beta-sarcoglycan (β-SG) gene expression in participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- EMERGENE (NCT06246513)
- Testing
- SRP-9003, Glucocorticoid
- Where
- 10 sites in United States, Belgium and 4 more
- Volunteers
- 17 people
- Sponsor
- Sarepta Therapeutics, Inc.
Clubfoot
Percutaneous Achilles Tendon Tenotomy vs Tendo-Achilles Lengthening (TAL) in Neglected Clubfoot Children.
Achilles tendon tenotomy is the established worldwide gold standard for correcting idiopathic clubfoot. However, in neglected cases, surgical interventions such as percutaneous Achilles tendon tenotomy (PAT) and open…
- Trial name
- NCT07561697
- Testing
- Tenotomy of Achilles Tendon, Tendo-Achilles Lengthening
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Muhammad Aamir Latif
Duchenne Muscular Dystrophy
Validity and Reliability of the 6 Minute Pegboard Ring Test
This study aimed to investigate the validity and reliability of 6PBRT in individuals with DMD and its applicability on these patients.
- Trial name
- NCT06174025
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Çağtay Maden
Cerebral Palsy
Upper Extremity Strength in Cerebral Palsy
Rationale: Children with Cerebral Palsy (CP) experience limitations in motor activities and participation in the community, predominantly caused by impairments in muscle function.
- Trial name
- NCT02146989
- Testing
- reproducibility of upper extremity strength measurements
- Where
- 9 sites in Netherlands
- Volunteers
- 370 people
- Sponsor
- Maastricht University Medical Center
Foot Deformities, Flatfoot
Translation, Cross-cultural Adaptation, and Validation of the FPI-6 in Spain
The objective of this study is to translate, cross-culturally adapt, and validate the Spanish version of the Foot Posture Index (FPI-6).
- Trial name
- FPI-6-ES (NCT07590297)
- Testing
- Spanish version of the Foot Posture Index (FPI-6)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paloma López Ros
Hemiplegia and Hemiparesis, Cerebral Palsy Infantile
Effectiveness of the Functional Hand Splint and Specific Tasks in the Domiciliary Environment Applied to Children With Unilateral Cerebral Palsy
The main objective: To determine the effectiveness of a treatment that combines the application of a functional upper limb orthosis together with a home-based program of specific tasks in children with unilateral cerebral palsy…
- Trial name
- NCT03282422
- Testing
- Home-based protocol in specific tasks, Upper-limb splint
- Where
- 2 sites in Spain
- Volunteers
- 33 people
- Sponsor
- Universidad San Jorge
Cerebral Palsy Infantile, Upper Limb Spasticity
Peripheral Neurotomies of the Upper Limb in Children With Cerebral Palsy.
Cerebral palsy (CP) is the leading cause of neurological disability in children, with a prevalence of 2-2.5 per 1,000 live births in Europe.
- Trial name
- PN-ULCP (NCT07915466)
- Testing
- Peripheral neurotomy of the upper limb (musculocutaneous and/or median and/or ulnar).
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Hospices Civils de Lyon
Syndromic Ichthyoses, CHILD Syndrome
Novel Treatment for Syndromic Ichthyoses
This is an open label-pilot study to assess the efficacy and safety of a novel cholesterol-lovastatin topical solution in children with rare syndromic ichthyoses.
- Conditions
- Syndromic Ichthyoses, CHILD Syndrome, Smith Lemli Opitz Syndrome, Conradi Syndrome
- Trial name
- NCT01110642
- Testing
- Lovastatin
- Sponsor
- Northwestern University
Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder
Virtual Reality-Augmented Constraint-Induced Movement Therapy Versus Conventional Constraint-Induced Therapy for Upper Limb Rehabilitation in Children With Unilateral Cerebral Palsy.
Cerebral palsy (CP) causes persistent motor and postural impairments that can limit children's functional independence and participation.
- Conditions
- Cerebral Palsy Spastic Hemiplegic, Functionnal Neurological Disorder, Upper Limb Functions, Virtual Reality Based Therapy
- Trial name
- NCT07853937
- Testing
- Rehabilitation intervention
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Faculty of Medicine, Sousse
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