Clinical trials: Extremity
Stroke, Stroke Acute
Research on the Effectiveness of Neurorehabilitation After Stroke
This clinical trial aims to investigate the effectiveness of a novel neurorehabilitation technology for treating stroke in adults.
- Conditions
- Stroke, Stroke Acute, Stroke with Hemiparesis, Stroke, Acute
- Trial name
- NCT06753006
- Testing
- Neurorehabilitation simulator, Standard course
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Neurotechnika
Diabetic Neuropathy Peripheral
Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy
Part A of this trial is a multi-center, prospective, double-blinded, sham-controlled, randomized clinical trial. Part A will evaluate PEMF treatment compared to sham treatment in patients with painful diabetic distal symmetric…
- Trial name
- RELIEF (NCT03455543)
- Testing
- Active Provant Therapy System
- Where
- 18 sites in United States
- Volunteers
- 182 people
- Sponsor
- Regenesis Biomedical, Inc.
Parkinson Disease
High-intensity Interval Circuit Training in People With Parkinson Disease
The goal of the study is to compare different types of high intensity circuit exercises over an 8-class training series in people with Parkinson disease.
- Trial name
- NCT06576817
- Testing
- High intensity circuit exercise class - Lower and upper extremity, High intensity circuit exercise class - Lower extremity alone
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Pacific Northwest University of Health Sciences
Post-Stroke Spasticity
A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)
The goal of this clinical trial is to learn if the drug BMS-986368 works to treat post stroke spasticity in adults who have had a stroke.
- Trial name
- STIPS (NCT07704840)
- Testing
- Administration of BMS-986368
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Alberto Esquenazi
Neuroma, Phantom Limb Pain After Amputation
Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Neuroma, Phantom Limb Pain After Amputation, Stump Pain, Platelet-rich Plasma (PRP)
- Trial name
- PRP-NEUROMA (NCT07624890)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Local Anesthetic Injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Fatigue
Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults
The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic…
- Trial name
- NCT04938791
- Testing
- Isometric activity
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
Parkinson Disease
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome.
- Trial name
- NCT06738290
- Testing
- Targeted home-based touchscreen training
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Chronic Neck Pain
Pain, Fear of Movement, Neck Awareness and Upper Extremity Functionality in Chronic Neck Pain
Our study aims to investigate the parameters related to pain catastrophizing, fear of movement, neck awareness and upper extremity functionality in individuals with chronic neck pain - a cross-sectional study.
- Trial name
- NCT07247214
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Peripheral Arterial Disease
DOTAREM®-Enhanced MRA Compared to GADOVIST®-Enhanced MRA in Patients With Abdominal or Lower Limb Arterial Diseases
This study is an intra-individual comparison of DOTAREM®-enhanced MRA and GADOVIST®-enhanced MRA in the diagnosis of clinically significant abdominal or lower limb arterial diseases.
- Trial name
- NCT00955617
- Testing
- Contrast-enhanced MRA - Imaging examination
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Guerbet
Upper Extremity Problem
Ultrasound-Guided Erector Spinae Plane Block Following Upper Extremity Surgery
Postoperative pain is important following upper extremity surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.Ultrasound (US)-guided brachial plexus blocks such as interscalen…
- Trial name
- NCT04083274
- Testing
- Erector spinae plane block (Group E)
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Stroke, Healthy
fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects
Background: Following a stroke, as part of neurorehabilitation, the intensity of effort is important to promote neural changes and stimulate motor recovery.
- Trial name
- BIROBONIRS (NCT06116006)
- Testing
- Upper limb pointing movements in 3 experimental conditions
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Spinal Cord Injuries
Upper Limb Spinal Cord Stimulation for Rehabilitation Enhancement
In the United Kingdom, there are more than 1000 new cases of spinal cord injury (SCI) each year, with around half of these injuries affecting the cervical spine.
- Trial name
- Up-Stim (NCT05991804)
- Testing
- Transcutaneous spinal cord stimulation added to inpatient rehabilitation
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Cerebral Palsy
VR Versus Plyometric Exercise on Lower Limb Motor Control and Balance in Spastic Hemiplegic Children
To investigate and compare the effect of Virtual reality and Polymetric exercises on balance, selectivity of the lower extremity and quality of life in children with spastic cerebral palsy.
- Trial name
- NCT07827404
- Testing
- Virtual reality (VR), Plyometric exercises
- Volunteers
- 44 people
- Sponsor
- October 6 University
CAD
Effect of Phase I Cardiac Rehab With or Without Upper Limb Cycle Ergometer
The aim of the study is to investigate the effects of an upper limb cycle ergometer in phase I CABG patients. This will likely enhance various outcomes such as quality of life, dyspnea, functional outcome measure, cardiovascular…
- Trial name
- NCT07128849
- Testing
- upper limb exercise with arm ergometer, upper limb exercise with out arm ergometer
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Stroke
Passive Robots for Stroke Rehabilitation: A Feasibility Study
The purpose of this study is to examine the feasibility and effectiveness of a novel, multimodal approach that combines passive devices with noninvasive neuromuscular stimulation for upper extremity rehabilitation after stroke.
- Trial name
- NCT07218276
- Testing
- Functional Training with SepaRRo and NeuRRoFES
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Occlusion of the Femoral-popliteal Segment, Femoral Access
Choosing an Access for Endovascular Treatment of Femoral-popliteal Segment Occlusions
The aim of this study is to compare the shoulder and femoral approaches used in the endovascular treatment of occlusive lesions of the femoral-popliteal segment of the lower extremity arteries in terms of the frequency of…
- Conditions
- Occlusion of the Femoral-popliteal Segment, Femoral Access, Brachial Access
- Trial name
- ATFA (NCT07694050)
- Testing
- Brachial artery catheterization, Femoral artery catheterization
- Where
- Russia
- Volunteers
- 304 people
- Sponsor
- Pirogov Russian National Research Medical University
Stroke
Comparison of Tele-rehabilitation Versus In-clinic Rehabilitation for Upper Limb Motor Function Stroke Patients
To determine the effects of Tele-rehabilitation versus in-clinical rehabilitation for upper limb motor function and spasticity in chronic ischemic stroke patients.
- Trial name
- NCT05875818
- Testing
- In-clinic Rehabilitation, Tele-rehabilitation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Superior University
Essential Tremor
Kinematic-based BoNT-A Injections for Bilateral ET
The primary objective is to study the efficacy of botulinum toxin type A (Xeomin®) injected utilizing kinematically-based injection parameters for the treatment of upper extremity essential tremor (ET).
- Trial name
- NCT02551848
- Testing
- Botulinum toxin type A
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Western University, Canada
Stroke
Augmenting Cerebral Blood Flow in Acute Ischemic Stroke
The most common type of stroke is ischemic (lack of blood flow to the brain due to a clot blocking a blood vessel). Time is brain and an average of 1.9 million brain nerve cells per minute are destroyed in patients experiencing a…
- Trial name
- NCT06911385
- Testing
- Arm Remote Ischemic Conditioning plus Pneumatic Compression lower limb
- Volunteers
- 150 people
- Sponsor
- University of Alberta
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