Clinical trials: Extremity
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Pes Planus
Low Dye Taping Technique and Temporary Felt Insoles on Pain and Disability in Children With Pes Planus.
This study aims to determine comparative effects of low dye taping technique and temporary felt insoles on pain and disability in children with pes planus.
- Trial name
- NCT05764967
- Testing
- Low Dye Taping, Temporary Felt Insoles
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Soft Tissue Sarcoma
Post-Operative Chemoradiation for Extremity & Trunk Soft Tissue Sarcoma
The goal of this clinical research study is to learn if the combination of radiation therapy plus low dose doxorubicin chemotherapy given after surgery is effective in the treatment of sarcoma.
- Trial name
- NCT00502411
- Testing
- Doxorubicin, Radiation Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Clubfoot
Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)
The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be…
- Trial name
- NCT00474344
- Where
- 2 sites in United States, Canada
- Volunteers
- 370 people
- Sponsor
- University of British Columbia
Cerebral Palsy, Muscle Spasticity
Effects of Repeated Botulinum Toxin Injections in Children With Cerebral Palsy
One of the disorders observed in children with cerebral palsy (CP) is abnormal muscle tone, and the most common tone problem is spasticity.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Vascularization
- Trial name
- NCT05295563
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Gazi University
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Limb Injury
X-rays Trauma Request's by the Triage And Intake Nurse Intake and Referral Nurse:
The number of consultations in emergency departments is increasing day by day, and the time to treat patients is getting longer.
- Trial name
- DARIO (NCT05669157)
- Testing
- Radiography request by nurse, Radiography request by physician
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Exercise Addiction, Trunk Muscle Strength
The Effect of Core Stabilization Exercises in Female Wrestlers
This study was planned to investigate the effect of core stabilization exercise program on trunk muscle strength, spinal stability and upper extremity performance in elite wrestling athletes.
- Conditions
- Exercise Addiction, Trunk Muscle Strength, Upper Extremity, Wrestling
- Trial name
- NCT06244030
- Testing
- core stabilization group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Okan University
Deformity, Defect, Congenital
Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Orthofix Srl put the JPS on the European market (2019) by the mean of a pre-market clinical evaluation made under the Medical Device Directive (MDD) requirements that were based on the analysis of the scientific literature of…
- Conditions
- Deformity, Defect, Congenital, Trauma
- Trial name
- JPS (NCT05245617)
- Testing
- JuniOrtho™ Plating System™
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Orthofix s.r.l.
Cerebral Palsy
Initial Outcomes of Robotic Lower Extremity Exoskeleton Use by a Non-ambulatory Child With CP
There are very few evidence-based interventions for children with cerebral palsy who cannot walk. The Trexo-Home is a device that is newly available for rent by families, but its impact is unknown.
- Trial name
- NCT04251390
- Testing
- trexo Home
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Calgary
Lower Extremity Muscles Biomechanical Properties and Joint Range of Motion in Swimmers
Comparison of Lower Extremity Parameters in Monofin and Bi-fin Swimmers.
The purpose of this study is to compare the leg muscle features and joint movements of swimmers who use a single large fin (monofin) versus those who use two fins (bi-fins).
- Trial name
- NCT07621913
- Testing
- Measuring of the biomechanical properties of muscles with MyotonPro, Measurement of the length of the lower extremity with a tape measure., Measuring the range of motion of the lower extremity joints with a digital goniometer
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Limb-girdle Muscular Dystrophy
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4
This is a multicenter, global study of the effects of a single systemic dose of SRP-9003 on beta-sarcoglycan (β-SG) gene expression in participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- EMERGENE (NCT06246513)
- Testing
- SRP-9003, Glucocorticoid
- Where
- 10 sites in United States, Belgium and 4 more
- Volunteers
- 17 people
- Sponsor
- Sarepta Therapeutics, Inc.
Upper Extremity Fracture
Brachial Plexus Block in Children and Adolescents
This study involves a retrospective evaluation of brachial plexus anaesthesia in children and adolescents (patients under the age of 18) undergoing surgical procedures of the upper extremity following trauma.
- Trial name
- NCT03842423
- Testing
- Brachial Plexus Anaesthesia
- Where
- Austria
- Volunteers
- 2,760 people
- Sponsor
- Medical University of Vienna
IV Drug Usage
Efficiency of IV Dexamethasone, Administered After a Lower Limb Blockade, on the Post Operative Pain in Children
Intravenous dexamethasone (IV) can be used alone in adults as an adjunct to peri-nerves blocks, for diffusion blocks. In pediatrics, dexamethasone is used daily according to the assessment of the anesthetist, by extension of the…
- Trial name
- DEXPED (NCT03618173)
- Testing
- Dexamethasone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Craniosynostoses, Crouzon Syndrome
ASO Treatment for Syndromic Craniosynostoses
Syndromic craniosynostoses (SCS) are rare genetic disorders defined by premature cranial suture fusion, resulting in abnormal craniofacial development and constrained brain growth.
- Conditions
- Craniosynostoses, Crouzon Syndrome, Saethre Chotzen Syndrome, Muenke Syndrome
- Trial name
- NAUTILUS (NCT07535372)
- Testing
- Design of patient specific ASO
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstetric Brachial Plexus Injury
The Effects of Virtual Reality Patients With Obstetric Brachial Plexus Injury
Obstetric brachial plexus injury is the flask paralysis of the arm, which emerges from a difficult birth. This results from the damage to the nerves from the C5 cervical root to T1.
- Trial name
- NCT04605601
- Testing
- Virtual reality treatment, conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Emine Atıcı
Bone Neoplasm, Rehabilitation
Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.
The aim of the present study is to describe the course of functional recovery of patients with musculoskeletal tumours and undergone resection and reconstruction operations of lower limbs in the first six months post-surgery…
- Trial name
- FISIO-ONCO (NCT06376539)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lysosomal Storage Disease, Cholesterol Metabolism
Study of Inborn Errors of Cholesterol Synthesis and Related Disorders
This study will investigate the cause and medical problems associated with a group of genetic disorders known as inborn errors of cholesterol synthesis, in which the body does not produce cholesterol.
- Trial name
- NCT00046202
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Milk Allergy
Characteristic and Evolution of an Atypical IgE-mediated Cow Milk Allergy Form With Hands and Feet Angio-oedema
Cow milk allergy is one of the most frequent food allergy among children. Cow milk protein's avoidance is needed until spontaneous recovery during the two first years of life.
- Trial name
- IgE-CMA (NCT04318483)
- Testing
- survey
- Volunteers
- 121 people
- Sponsor
- Fondation Lenval
Cerebral Palsy
"DOES MYOBLOC™ IMPROVE FUNCTIONAL HAND USE IN YOUNG CHILDREN WITH A HYPERTONIC UPPER EXTREMITY?"
In children with cerebral palsy, stiffness of the arm can develop early and delay or prevent the acquisition of normal hand skills.
- Trial name
- NCT00238641
- Testing
- Botulinum Toxin type B
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
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