Clinical trials: Extremity
Cutaneous Melanoma, Anatomical Pathological Condition
Location of Lower Limb Cutaneous Melanomas as a Prognostic Factor.
Observational study to know the relevance of specific anatomical location of cutaneous melanoma on lower limbs.
- Trial name
- NCT04625491
- Testing
- Observational
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Cardiac Surgery, Central Venous Catheter Thrombosis
Continuous Heparin Infusion to Prevent Catheter-related Thrombosis
Catheter-related thrombosis could impair blood flow in the vein, block the central venous catheter, induce catheter-related infection or venous thromboembolism in the deep veins or pulmonary vessels, which furthermore progress…
- Conditions
- Cardiac Surgery, Central Venous Catheter Thrombosis, Heparin
- Trial name
- NCT04767113
- Testing
- Heparin sodium, Normal saline
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Guangdong Provincial People's Hospital
Chronic Limb-Threatening Ischemia, Colorectal Carcinoma
Comparison of Outcomes of Patients With Stage IV Chronic Limb-threatening Ischemia and Colorectal Cancer
Colorectal cancer (CRC) and chronic limb-threatening ischemia (CLTI) are relatively frequent and potentially fatal diseases. However, studies that are comparing clinical outcomes between CRC and CLTI patients in more advanced…
- Conditions
- Chronic Limb-Threatening Ischemia, Colorectal Carcinoma, Colorectal Carcinoma Metastatic in the Liver
- Trial name
- NCT05116696
- Testing
- For chronic limb-threatening ischemia (CLTI) patients revascularisation surgery; for colorectal liver metastasis (CRLM) patients metastatic liver surgery
- Where
- Serbia
- Volunteers
- 836 people
- Sponsor
- Clinical Centre of Serbia
Sarcoma, Myxofibrosarcoma
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm or leg using a technique called…
- Conditions
- Sarcoma, Myxofibrosarcoma, Undifferentiated Pleomorphic Sarcoma, Alveolar Soft Part Sarcoma
- Trial name
- NCT04332874
- Testing
- Isolated Limb Infusion, Pembrolizumab, infusion of melphalan and dactinomycin
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Invasive Meningococcal Disease
Can we Reduce the Number of Vaccine Injections for Children?
This open label randomised controlled study will evaluate the induction of immunity following varying schedules of vaccination with glyco-conjugate Neisseria meningitidis serogroup C (MenC) vaccines in infancy.
- Trial name
- MALTA (NCT01129518)
- Testing
- Glyco-conjugate Neisseria meningitidis serogroup C (MenC) vaccine, Routine schedule immunisations except monovalent MenC vaccine
- Where
- United Kingdom
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cerebral Palsy, Spastic
Effect of Pully System on Hemiplegic Children
Introduction Cerebral palsy (CP) is a group of sensory, motor, and postural disorders caused by non-progressive brain injury in early development.
- Trial name
- NCT06434246
- Testing
- pulley system exercise regimen, physical therapy program for CP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kafrelsheikh University
Lower Urinary Tract Symptoms, Posture Disorders in Children
Examination of Trunk and Lower Extremity Biomechanics in Children With LUTD.
This study aimed to examine trunk and lower extremity biomechanics among children with lower urinary tract dysfunction (LUTD). It was targeted to pioneer including biomechanical changes into treatment if detected in the trunk and…
- Conditions
- Lower Urinary Tract Symptoms, Posture Disorders in Children, Muscle Weakness Condition, Urinary Incontinence in Children
- Trial name
- NCT05299827
- Testing
- The same evaluation methods were used for both groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Neuromotor Impairments
Physical Therapy for Montana Children With NMD Using Hippotherapy and the Equine Environment
The goal of this pilot clinical trial is to determine if physical therapy incorporating horses can improve the motor skills of the arms in children 6-17 years old with neuromotor disorders (such as cerebral palsy, spinal muscular…
- Trial name
- NCT06887647
- Testing
- Physical Therapy Using Hippotherapy and the Equine Environment, Standard Play-Based Physical Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Montana
Hemiplegic Cerebral Palsy, Mirror Hands
Mirror Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder that frequently impairs upper extremity motor control and hand function, resulting in limitations in daily activities.
- Conditions
- Hemiplegic Cerebral Palsy, Mirror Hands, Upper Extremity Dysfunction, Motor Activity
- Trial name
- NCT07734376
- Testing
- Mirror Therapy, Conventional Physiotherapy
- Volunteers
- 26 people
- Sponsor
- Marmara University
Lower Limb Ischaemia
Nasal High Flow Oxygen in Patients With Lower-Limb Ischaemia
A prospective, single arm pilot efficacy study designed to evaluate the physiological and symptomatic effects of normobaric Nasal High Flow (NHF) oxygen therapy in patients with lower limb ischaemia experiencing rest pain and/or…
- Trial name
- NCT07891208
- Testing
- Nasal high flow oxygen
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Pediatrics, Muscle Spasticity
BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity
This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric upper limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
- Trial name
- NCT01603615
- Testing
- Botulinum Toxin Type A
- Where
- 48 sites in United States, Canada and 7 more
- Volunteers
- 220 people
- Sponsor
- Allergan
Idiopathic Clubfoot (Talipes Equinovarus)
A Double-Blind, Randomized Control Trial Comparing Botulinum Toxin Type A (Botox) and Placebo in the Treatment of Idiopathic Clubfoot
The purpose of this study is to continue the work from the previous review study and determine the effectiveness of Botox in treating patients with idiopathic clubfoot by comparing outcomes of subjects treated with manipulation…
- Trial name
- NCT00152347
- Testing
- Botox
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of British Columbia
Evaluation of a New Prosthetic Socket Liner Material.
Evaluation of the Development of an Advanced, Conformable Prosthetic Socket, Study I
The purpose of this study is obtain prosthetist's feedback on the novel conformable socket material developed by Infoscitex, and determine if it is a viable alternative to current prosthetic socket liners.
- Trial name
- NCT01309347
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Infoscitex Corporation
Scoliosis
Relationship Between Spine Coronal Alignment and Lower Limb Biomechanical in Scoliosis
To examine the relationships between spine coronal alignment and lower limb biomechanical parameters in scoliotic adolescents
- Trial name
- NCT06276972
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 89 people
- Sponsor
- Delta University for Science and Technology
Stroke
AdaptRehab imVR: Exploring the Feasibility of imVR for Upper Limb Stroke Rehabilitation in Ethiopia
Stroke is a major cause of long-term disability worldwide, particularly in low- and middle-income countries (LMICs). Upper limb impairments following stroke can substantially limit an individual's ability to perform daily…
- Trial name
- imVR (NCT07412899)
- Testing
- Virtual Reality Headset with immersive exercises.
- Where
- Ethiopia
- Volunteers
- 18 people
- Sponsor
- Jimma University
Cerebral Palsy, Prosthesis User
Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy
The purpose of the study is to assess the effectiveness of an upper extremity prosthesis in improving the upper extremity function of children with cerebral palsy who have limited use of their hands.
- Trial name
- NCT03122171
- Testing
- Occupational Therapy Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Cerebral Palsy
Project Falcon: Exploring a Virtual Reality-based Video Game for Young People With Cerebral Palsy
This study seeks to 1) adapt a low-cost controller, the Novint Falcon, and a set of video games that would provide rehabilitative feedback for young people with cerebral palsy, and 2) explore feasibility of the Falcon system and…
- Trial name
- NCT04298411
- Testing
- Falcon
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Congenital Muscular Torticollis
The Effects of Weight Shift Training on the Symmetry of Upper Extremity Weight Bearing in the Prone Position in Infants With Congenital Muscular Torticollis
Congenital muscular torticollis(CMT) is a common musculoskeletal condition in infancy that may result in asymmetrical posture and weight-bearing patterns, limited cervical range of motion, and delayed motor development.
- Trial name
- NCT07663721
- Testing
- Weight Shift Training, Stretching Exercise
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Sahmyook University
CHILD Syndrome
Effects of Alexander Technique in Children With Upper Cross Syndrome.
This randomized clinical trial will involve 50 participants aged 13 to 16, recruited from Faisal Hospital Faisalabad and different schools nearby.
- Trial name
- NCT07248748
- Testing
- Alexander technique, Corrective exercises
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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