Clinical trials: Extremity
Cerebral Palsy
Effectiveness of Unilateral Versus Bilateral Intensive Training in Children With Cerebral Palsy
This 3-year research project aims to investigate and compare the immediate and long-term treatment effectiveness as well as motor improving curve and potential predictors of the unimanual intensive training and bimanual intensive…
- Trial name
- NCT02808156
- Testing
- unilateral upper limbs intensive training, bilateral upper limbs intensive training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Postural Orthostatic Tachycardia Syndrome (POTS), Syncope
Abdominal and Lower Extremity Compression During Tilt Table Testing in Adolescent POTS Patients
Postural orthostatic tachycardia syndrome (POTS) is a common cause of orthostatic intolerance in adolescents and adults. Compression stockings are commonly recommended as a treatment modality for POTS, but the effects of…
- Trial name
- NCT01795469
- Testing
- Zoex compression garment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nationwide Children's Hospital
Trauma Patients
Limb Salvage in Peripheral Arterial Trauma Patients
The aim of this study is to determine risk factors associated with failure of limb salvage in patients with periphral arterial injuries with or without attempts of revascularization.
- Trial name
- NCT06787495
- Testing
- Arterial repair
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mekhael Rezk Abd-Elmalak
Lower Limb Ischemia
Endovascular Management of Combined Common Femoral and Superficial Femoral Arteries Lesions
The purpose of this study is to evaluate the technical feasibility, safety, and 1-year clinical efficacy of the endovascular treatment of patients with atherosclerotic common femoral artery (CFA) obstructions with associated…
- Trial name
- NCT05569369
- Testing
- angioplasty and stenting
- Volunteers
- 25 people
- Sponsor
- Sohag University
Multiple Sclerosis, Spasticity, Muscle
" Treating MS Patients With Lower Extremity Spasticity Using Dysport"
The purpose of this study is to determine whether Dysport® (abobotulinumtoxinA) injections for lower extremity spasticity showed a significant reduction of lower extremity spasticity after being injected with Dysport®…
- Trial name
- NCT03585569
- Testing
- Abobotulinumtoxin A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Neurology Center of New England P.C.
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3
Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb
Spinal cord stimulation (SCS) has shown remarkable efficacy in restoring motor function in people with spinal cord injury by recruiting afferent input to enhance the responsiveness of spared neural circuits to residual cortical…
- Conditions
- Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy 4
- Trial name
- NCT06300996
- Testing
- Spinal Cord Stimulator (Octopolar Medtronic Vectris Leads)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Marco Capogrosso
Necrotizing Fasciitis
Outcome and Related Factors of Necrotizing Fasciitis of the Limb
Soft tissue necrotizing fasciitis of limbs are lethal infections and associated with high morbidity and mortality rates. The purpose of this study is to determine the clinical manifestations and factors affected the treatment…
- Trial name
- NCT00538577
- Where
- Iran
- Volunteers
- 25 people
- Sponsor
- Tehran University of Medical Sciences
Clubfeet, Adolescent Idiopathic Scoliosis
Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet
While studies have shown that better outcomes are associated with brace wear compliance in the scoliosis and clubfoot populations, compliance rates are still poor.
- Trial name
- NCT02755766
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Shriners Hospitals for Children
Hemiplegic Cerebral Palsy
Virtual Reality With Mirror Therapy on Upper Limb Function
The goal of this clinical trial is to address the effect of (Virtual Reality) and (Mirror Therapy) together on upper limb function in hemiplegic Cerebral Palsy children , male or female ranged between 3 to 10 years of age .
- Trial name
- NCT06728475
- Testing
- virtual reality, mirror therapy, virtual reality with mirror therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Limb-Girdle Muscular Dystrophy, Social Competence
Telecare Psychosocial and Cognitive Intervention for Children and Adolescents With Limb-Girdle Muscular Dystrophy
This clinical trial aims to evaluate the efficacy of a telecare-mediated psychosocial and cognitive intervention for children and adolescents aged 7 to 17 with limb-girdle muscular dystrophy.
- Conditions
- Limb-Girdle Muscular Dystrophy, Social Competence, Self Esteem, Health Related Quality of Life
- Trial name
- TPCLGMD (NCT07711730)
- Testing
- Neuro-psychosocial teleassistance program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Deusto
Upper Limb Deformities, Congenital
Customized Self-Controlled Power-Driven or Mechanical Orthoses for the Upper Limb - A Pilot Study
Patients with congenital or acquired upper limb structural abnormalities and peripheral nerve or brachial plexus palsies have significant loss of function.
- Trial name
- NCT04199975
- Testing
- Orthoses
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Tendinopathy
The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy
The purpose of this study is to determine differences in lower extremity landing biomechanics and real-world physical activity between individuals with patellar tendinopathy compared to individuals without patellar…
- Trial name
- NCT03262181
- Testing
- Isometric Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Erb's Palsy
Neuromuscular Electrical Stimulation With and Without Constraint Induced Movement Therapy in Erb's Palsy
Erb's Duchenne paralysis constitutes the single commonest form of brachial plexus injury, brachial plexus injury (BPI) is unfortunately a rather common injury in newborn children.
- Trial name
- NCT05723042
- Testing
- EMS with CIMT, EMS
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Osteomyelitis Chronic, Bone Defects
Pre-Surgery Rehab for a Child With Humeral Head and Shaft Deformity: A Case Report
The goal of this observational study (single-patient case report) is to learn whether a structured pre-operative physical therapy rehabilitation program can improve shoulder function, reduce pain, and improve quality of life in…
- Trial name
- NCT07283302
- Testing
- Transcutaneous Electrical Nerve Stimulation, Low-Level Laser Therapy, Manual Therapy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Cairo University
Muscular Dystrophies, Limb-Girdle
A Study of SRP-9005 in Limb Girdle Muscular Dystrophy Type 2C/R5 Pediatric and Adult Participants
This is a study of a single systemic dose of SRP-9005 in pediatric and adult participants with limb girdle muscular dystrophy type 2C/R5 (LGMD2C/R5).
- Trial name
- COMPASS (NCT06952686)
- Testing
- SRP-9005, Corticosteroid
- Where
- United States
- Sponsor
- Sarepta Therapeutics, Inc.
Stroke
Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke Patients
RATIONALE: The previous study resulted that the gait training using Functional Electrical Stimulation (FES) improved the ankle joint function and the walking ability for the chronic stroke patients with foot drop.
- Trial name
- PLEASURE (NCT02897752)
- Testing
- gait training with WA, usual gait training
- Where
- 24 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Hearing Impaired Children
Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment
Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving.
- Trial name
- NCT06198049
- Testing
- Pilates Training, Balance Proprioception Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Spinal Muscular Atrophy (SMA)
Effects of Different Stiffness Settings During Robotic Isokinetic Training in Children With SMA
This randomized, within-participant, contralateral-limb-controlled clinical trial will compare individually optimized compliant and rigid stiffness settings of a portable isokinetic knee training robot in children with spinal…
- Trial name
- NCT07822711
- Testing
- Portable Isokinetic Knee Training Robot With an Individually Optimized Compliant Setting, Portable Isokinetic Knee Training Robot With a Rigid Setting
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
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