Clinical trials: Eye Care
Myopia, Conjunctivitis
Zanzibar Arts for Children's Eyesight Pilot Trial
In Zanzibar, around 22,000 children (4% of those aged 6 to 12) need treatment for eye issues like conjunctivitis or require glasses. A 2017 study found that 42% of rural children needing glasses didn't have them.
- Conditions
- Myopia, Conjunctivitis, Hyperopia
- Trial name
- ZANZI-ACEII (NCT06469697)
- Testing
- School music broadcast, Community music broadcast
- Where
- Tanzania
- Volunteers
- 1,295 people
- Sponsor
- Queen's University, Belfast
Autism
Validation of Indiana's Early Evaluation Hub System
The investigators' objective is to test an innovative method of autism diagnosis that integrates clinical evaluation and assessment of biobehavioral markers in a large high-risk community-referral sample of children in the…
- Trial name
- EAER21 (NCT06586788)
- Testing
- Eyelink Portable Duo, Integrated PCP Diagnosis and Eye-tracking Biomarker
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- Indiana University
Amblyopia, Strabismus
Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening
Amblyopia ("lazy eye") and strabismus (misaligned eyes) are medical eye conditions that combine as the leading causes of preventable vision loss in children.
- Trial name
- NCT02536963
- Testing
- Pediatric Vision Scanning device, Reference examination
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Retinopathy of Prematurity (ROP)
Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP)
The main purpose of this study is to evaluate the long-term efficacy and safety outcomes following short-term exposure to rhIGF-1/rhIGFBP-3 versus standard neonatal care in Study ROPP-2008-01 (NCT01096784).
- Trial name
- PEDAL (NCT02386839)
- Testing
- rhIGF-1/rhIGFBP-3
- Where
- 16 sites in United States, Italy and 4 more
- Volunteers
- 76 people
- Sponsor
- Shire
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Cortical Visual Impairment
Remote Access: Cortical Visual Impairment
This study aims to compare the efficacy of an in-home telehealth-based intervention to standard care for children with cortical visual impairment and their caregivers and to assess the feasibility and acceptability of an in-home…
- Trial name
- NCT03957980
- Testing
- Occupational therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myopia, Outdoor Activity
Vision Care Intervention for Lower Grade School Children in Taiwan
The purpose of this study is making use of school policy- recess outside classroom (ROC7-11) for increasing the time spent outdoor during recess and encouraging children spent time outdoor up to 11 hours in each week to…
- Conditions
- Myopia, Outdoor Activity, Policy of Recess Outside Classroom
- Trial name
- NCT02082743
- Testing
- Outdoor activity in recess time
- Where
- Taiwan
- Volunteers
- 1,020 people
- Sponsor
- Chang Gung Memorial Hospital
Stress, Psychological, Inflammatory Bowel Diseases
Introduction of Microsystems in a Level 3 Neonatal Intensive Care Unit
The advancement in life-saving technologies and clinical expertise in the care of extremely premature infants, have resulted in the development of large neonatal intensive care units (NICU).
- Conditions
- Stress, Psychological, Inflammatory Bowel Diseases, Lung Diseases, Infant Nutrition Disorders
- Trial name
- NCT02912780
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McMaster Children's Hospital
Quality Improvement, Appointments and Schedules
Enhancing Operational Efficiency in Eye Care Services
Pushpagiri Vitreo Retina Institute (PVRI) based in Secunderabad is a tertiary care eye hospital providing specialty eye care services since 2007.
- Conditions
- Quality Improvement, Appointments and Schedules, Operations Research Workflow
- Trial name
- NCT07416864
- Testing
- Health service Optimization
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Seva Canada Society
Glaucoma
Patient Performance on Virtual Reality Visual Field Devices as Compared to Standard of Care
The purpose of this research is to study the effectiveness and patient experience when measuring visual fields using virtual reality goggles.
- Trial name
- NCT04994457
- Testing
- Virtual Reality Visual Field, Standard Automated Perimetry
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Miami
Amblyopia
CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY
Screening A child is considered for the study after undergoing a standard of care and study specific eye examinations (by a study investigator as part of standard of care) that identifies amblyopia appearing to meet the…
- Trial name
- NCT04785690
- Testing
- CureSight, Patching
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NovaSight
Anxiety, Strabismus
Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?
The hypothesis is that pediatric patients with increased levels of anxiety on the day of surgery, in particular at point of anesthetic induction, will demonstrate decreased compliance with assessment in ophthalmology clinic…
- Conditions
- Anxiety, Strabismus, Compliance
- Trial name
- NCT02704442
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Queen's University
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in gas permeable lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912781
- Testing
- FID 120947A contact lens disinfecting solution, Boston Simplus multi-action solution, Gas permeable contact lenses
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia
Pilot Study on the Adaptation and Tolerance of Essilor® Myopia-control Spectacle Lenses
This observational pilot study aims to evaluate the adaptation and tolerance of Essilor® Stellest® myopia-control spectacle lenses in children with progressive myopia.
- Trial name
- STELLAR (NCT07340931)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Retinopathy of Prematurity (ROP)
The Effect of Two Non-Pharmacological Methods on Pain During Retinopathy Examination
The goal of this randomized controlled trial is to determine the effect of reverse kangaroo care position and ROP (Retinopathy of Prematurity) position applied during ROP examination in premature infants on pain.
- Trial name
- NCT06694103
- Testing
- Reverse Kangaroo Care Position, ROP Position
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sinem Basdemir
Diabetic Retinopathy, Glaucoma
AI for the Detection of Retinal Disease and Glaucoma in Patients With Diabetes Mellitus in Primary Care
Background: Diabetic retinopathy (DR) is one of the most important causes of blindness worldwide, especially in developed countries.
- Conditions
- Diabetic Retinopathy, Glaucoma, Age-Related Macular Degeneration, Choroidal Nevus
- Trial name
- NCT04132401
- Testing
- algorithm
- Where
- Spain
- Volunteers
- 902 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Diabetes, Diabetic Retinopathy
Improve Timely Referral Flow and Compliance of Diabetic Retinopathy Patients
An effective referral system helps to ensure a close relationship between all levels of the health system and ensures clients receive optimum care at the appropriate level and at affordable cost, and hospital facilities are used…
- Trial name
- NCT04834648
- Testing
- Structured Counseling
- Where
- Nepal
- Volunteers
- 150 people
- Sponsor
- Seva Foundation
Viral Conjunctivitis
ADenoVirus Initiative Study in Epidemiology in Italy
The objectives of this study is to assess the characteristics and frequency of adenovirus conjunctivitis in a population of male and female patients from one year of age who present signs and symptoms of acute conjunctivitis.
- Trial name
- NCT03055065
- Where
- Italy
- Volunteers
- 241 people
- Sponsor
- NicOx
Retinopathy of Prematurity, Neurodevelopmental Disorders
Analyzing Retinal Microanatomy in ROP
Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that may impact vision in vulnerable preterm neonates for a lifetime.
- Conditions
- Retinopathy of Prematurity, Neurodevelopmental Disorders, Macular Edema
- Trial name
- BabySTEPS (NCT02887157)
- Testing
- Swept Source OCT, Magnetic Resonance Imaging, Scavenged blood collection
- Where
- 4 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Duke University
Strabismus
Japanese Strabismus Outcomes Assessment and Research Group Study
This retrospective study constructs the largest multicenter registry of strabismus care in Japan. The registry evaluates real-world surgical and conservative treatment outcomes, safety, and natural history for various types of…
- Trial name
- J-SOAR (NCT07763457)
- Testing
- Strabismus Surgery, Conservative Treatment or Observation
- Where
- Japan
- Volunteers
- 10,000 people
- Sponsor
- Kyoto University, Graduate School of Medicine