Clinical trials: Fetal Health
Mother-to-child Transmission of HIV, Pregnancy
Trial to Improve Access to PMTCT Services and Reduce HIV Transmission From Mother to Child
The purpose of this study is to determine the effectiveness, cost-effectiveness, feasibility and acceptability of an enhanced community health worker (CHW) intervention and outreach system to improve antenatal care and PMTCT…
- Trial name
- FS (NCT01932138)
- Testing
- Enhanced CHW intervention, Standard of care
- Where
- Tanzania
- Volunteers
- 190,530 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Pregnancy, HIV Infections
Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women
This study will evaluate the effectiveness of CenteringPregnancy Plus, a group prenatal care treatment program with an HIV/sexually transmitted disease prevention component, in reducing health risk behaviors in pregnant teenagers…
- Conditions
- Pregnancy, HIV Infections, Sexually Transmitted Diseases
- Trial name
- NCT00628771
- Testing
- CenteringPregnancy Plus (CP+), Usual care
- Where
- 3 sites in United States
- Volunteers
- 1,233 people
- Sponsor
- Yale University
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Antenatal Care
Ethiopia Group Antenatal Care Study at the Health Post Level
The purpose of this study is to determine the acceptability, feasibility, and effectiveness of a group antenatal care (G-ANC) model introduced at the health post level compared to usual antenatal care (ANC) among women who report…
- Trial name
- ARC004 (NCT05054491)
- Testing
- Group Antenatal Care
- Where
- Ethiopia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Digital Health, Maternal Health Services
The Effect of Digitally Enabled District (DED 2.0) Ecosystem on the Completeness and Timeliness of Maternal and Neonatal Services in Primary Health Care
DED 2.0 is a stepped-wedge cluster-randomized trial testing whether an integrated digital health ecosystem (KuApps, a service-monitoring dashboard, AI-assisted OCR for handwritten records, two-way WhatsApp-based health…
- Conditions
- Digital Health, Maternal Health Services, Prenatal Care, Intensive Care, Neonatal
- Trial name
- DED (NCT07842224)
- Testing
- Digitally Enabled District (DED)
- Where
- Indonesia
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia
Childhood Obesity Prevention
Anthropometric Outcomes of a Mobile Health Intervention for Eating Behaviour and Lifestyle in Infancy
Lifestyle, activity, and feeding behaviours during early childhood set the foundation for subsequent lifelong metabolic health as an adult.
- Trial name
- NCT06457750
- Testing
- Feeding, Lifestyle, Activity Goals (FLAGs) Digital Health Application
- Where
- Singapore
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Periodontal Disease
Influence of Periodontal Treatment During Pregnancy in Adverse Pregnant Outcomes
The aim of this study is to evaluate the effects of treatment of periodontal disease during the second trimester of gestation in adverse pregnancy outcomes.
- Trial name
- NCT00893802
- Testing
- Scaling and root planning
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Perinatal Mortality
Global Network Implementation of Helping Babies Breathe (HBB)
The primary purpose of this pre-post evaluation is to test the impact on perinatal mortality (fresh stillbirths or early neonatal deaths) among births > 1500g of training birth attendants at health facilities in the Helping…
- Trial name
- NCT01681017
- Testing
- HBB/ENC Training and Equipment, HBB/ENC supplies
- Where
- 3 sites in India, Kenya
- Volunteers
- 70,704 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Antenatal Care
Strategies to Increase Antenatal Iron and Folic Acid Supplementation and Malaria Prophylaxis
Pregnancy increases the risk of malaria and nutritional deficiency. Despite some progress in ANC access over the past years, coverage of antenatal iron and folic acid supplementation (AIFAS) and intermittent preventive treatment…
- Trial name
- AIFASMaP (NCT04250428)
- Testing
- Demand intervention, Supply intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Centre Suisse de Recherches Scientifiques en Cote d'Ivoire
Patient Satisfaction
Group Based Care Versus Individual Care
The Study compares group based care versus individual given care-effects on patient satisfaction and health. Midwives will be randomized to either traditional antenatal care (Individual care) or group based antenatal…
- Trial name
- GBAC (NCT01224275)
- Testing
- group based care
- Where
- Sweden
- Volunteers
- 1,150 people
- Sponsor
- Karolinska Institutet
Pregnancy
Impact of the Model Health Behaviour Mother 1000 Days of Life Health Online-Based on Prenatal, Intranatal, and Postnatal
The goal of this quasi-experimental interventional study is to learn whether an online-based Health Behavior Mother intervention during the first 1000 days of life can improve maternal care behavior in third-trimester pregnant…
- Trial name
- NCT07462585
- Testing
- the Model Health Behaviour Mother 1000 Days of Life Health Online-Based on Prenatal, Intranatal, and Postnatal
- Where
- Indonesia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Siti Saidah Nasution
Child Development, Early Child Development
Intergenerational Risk and Resilience of Rohingya in Displacement
The iRRRd study is an ongoing prospective longitudinal prenatal birth cohort study based in Cox's Bazar, Bangladesh. Between February 2023 and March 2024, 2,888 pregnant women were enrolled (approximately 80% Rohingya refugees…
- Conditions
- Child Development, Early Child Development, Mental Health, PTSD - Post Traumatic Stress Disorder
- Trial name
- iRRRd (NCT07758283)
- Where
- Bangladesh
- Volunteers
- 2,200 people
- Sponsor
- New York University
Antenatal Care, Pregnancy Complications
A Culturally Adapted Digital Intervention to Promote Maternal Care Utilization Using Multifaceted Approaches
Maternal healthcare utilization is crucial for reducing maternal mortality, yet remains low in many underserved regions. The CALCIUM intervention, a culturally tailored, digital platform-integrated intervention, was developed to…
- Conditions
- Antenatal Care, Pregnancy Complications, Pregnancy Outcomes
- Trial name
- NCT07091188
- Testing
- Health education, capacity building and economic incentives
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Jiayao Xu
Maternal Health Services
A Cluster Randomized Controlled Intervention to Improve Institutional Birth Rate in a Rural District of Ethiopia
Despite the efforts from the government, maternal healthcare services utilization is far below the recommended level in Ethiopia with a high urban-rural disparity.
- Trial name
- NCT05385380
- Testing
- Safe motherhood Promotion
- Where
- Ethiopia
- Volunteers
- 727 people
- Sponsor
- Prof Yves Jacquemyn
Stillbirth, Neonatal Death
Accelerating Newborn Survival in Ghana Through a Low-dose, High-frequency Health Worker Training Approach
This study assesses the effect of a low-dose, high-frequency training approach on long-term evidence-based skill retention among skilled birth attendants and impact on adverse birth outcomes at hospitals in Ghana.
- Trial name
- NCT03290924
- Testing
- Low dose high frequency health worker training approach, Active Comparison
- Volunteers
- 40 people
- Sponsor
- Jhpiego
Pregnancy, Fetal and Neonatal Health
Outcome of Fetal Spina Bifida
Neural tube defects are one of the most prevalent congenital abnormalities, surpassed only by cardiac malformations. Spina bifida accounts for the majority of the neural tube defects and is comprised of a wide spectrum of…
- Trial name
- NCT01100697
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- University of Luebeck
Partner HIV Testing, Couple HIV Counseling
Couple-oriented Prenatal HIV Counseling in Low and Medium HIV Prevalence Countries
ANRS 12127 Prenahtest is an intervention trial conducted in four countries (Cameroon, Dominican Republic, Georgia and India), where pregnant women are randomized during prenatal care to receive either standard post-test HIV…
- Conditions
- Partner HIV Testing, Couple HIV Counseling, Couple Communication, HIV Incidence
- Trial name
- Prenahtest (NCT01494961)
- Testing
- Couple-oriented post-test HIV counseling
- Where
- 4 sites in Cameroon, Dominican Republic and 2 more
- Volunteers
- 1,943 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Friedreich Ataxia
A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies
In this study, researchers will learn more about the safety of BIIB141, also known as omaveloxolone or SKYCLARYS. This is a drug available for doctors to prescribe for people with Friedrich's Ataxia, also known as FA.
- Trial name
- NCT06628687
- Testing
- Omaveloxolone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Biogen
Pregnancy Related
The Effects of Using Virtual Reality Glasses During the Non-Stress Test
The aim of this study to determine the effect of virtual reality glasses use on anxiety, stress and fetal well-being during the non-stress test.
- Trial name
- NCT05711875
- Testing
- Virtual Reality (VR) glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Inonu University
HIV Infection
Prevention, Access to Rights, Catch-up Vaccination, Treatment of Conditions During Pregnancy and for Children
Insufficient screening and diagnostic delay play a significant role in sustaining the HIV epidemic by France. Gender inequalities major factors reinforce social inequalities in order to of heterosexual men born abroad the most…
- Trial name
- PARTAGE (NCT05085717)
- Where
- France
- Volunteers
- 1,347 people
- Sponsor
- Raincy Montfermeil Hospital Group