Clinical trials: Fibroids
Uterine Fibroids (UF), Microwave Ablation
Safety and Efficacy of Microwave Ablation Alone Versus Microwave Ablation Combined With Chemical Ablation in the Treatment of Uterine Fibroids: A Prospective, Multicenter Study
Uterine fibroids are the most common benign tumors in women of reproductive age, with a prevalence of 20%-50%, often causing menorrhagia, anemia, pelvic pain, and pressure symptoms that markedly impair quality of life.
- Conditions
- Uterine Fibroids (UF), Microwave Ablation, Ultrasound
- Trial name
- NCT07754877
- Testing
- Microwave ablation combined with chemical ablation, Microwave ablation
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Aerospace Center Hospital
Myomectomy, Fibroid Uterus
Risk of Hysterectomy at Time of Myomectomy
Uterine fibroids are the commonest tumor affecting the female reproductive tract and many instances they are asymptomatic but in some women there does appear to be an association with heavy menstrual blood loss and possibly…
- Conditions
- Myomectomy, Fibroid Uterus, Hysterectomy
- Trial name
- NCT07365969
- Where
- Egypt
- Volunteers
- 293 people
- Sponsor
- Ain Shams University
Fibroid Uterus
Robot-Assisted Laparoscopic Myomectomy Is an Improvement Over Laparotomy in Patients With a Limited Number of Fibroids
This is a retrospective, case-control study of 75 patients having undergone a robotic-assisted laparoscopic myomectomy were compared to patients having undergone myomectomy via laparotomy.
- Trial name
- NCT00910468
- Testing
- Robot-assisted Laparoscopic myomectomy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ascher-Walsh, Charles, M.D.
Uterine Fibroid, Pregnancy Related
Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study
The frequency of women presenting with a combination of uterine fibroids and pregnancy is in-creasing nowadays. Uterine fibroids in pregnancy are an unfavorable condition in themselves and being reactive to hormonal stimuli…
- Trial name
- LPTM-UFs-P (NCT06009562)
- Testing
- Laparotomic myomectomy during pregnancy
- Where
- Russia
- Volunteers
- 28 people
- Sponsor
- University of Palermo
Uterine Leiomyoma
Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma
The investigators want to know whether the intravenous ascorbic acid would reduce the blood loss during laparoscopic myoma surgery.
- Trial name
- NCT01715597
- Testing
- ascorbic acid, Normal saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Leiomyomas
Diffusion -and Perfusion Weighted MRI for Response Prediction of Symptomatic Leiomyomas Following Uterine Artery Embolization
It is known that volumetric response of leiomyomas following uterine artery embolization correlates well with patients clinical outcome.
- Trial name
- NCT01514617
- Testing
- Diffusion -and perfusion weighted MRI including iv contrast agent injection
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Adenomyosis, Endometriosis
Risk Factors and Disorders Linked to Uterine Adenomyosis on MRI in Reproductive-Age Women
The goal of this observational case-control study is to identify risk factors and associated conditions related to adenomyosis in women of reproductive age.
- Conditions
- Adenomyosis, Endometriosis, Leiomyoma (Uterine Fibroids), Ovarian Cysts
- Trial name
- NCT06697444
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Mashhad University of Medical Sciences
Leiomyoma
Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids
The goal of this study is to develop additional long term data to evaluate the safety and effectiveness of this treatment. Indications for use for this system is: 'The ExAblate is intended to ablate uterine fibroid tissue in pre…
- Trial name
- NCT00131365
- Testing
- ExAblate 2000
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- InSightec
Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping
Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping: A Cross Sectional Observational Study
Three-Dimensional Ultrasonography versus Magnetic Resonance Imaging for Fibroid Mapping: A Cross sectional Observational study
- Trial name
- NCT05505331
- Testing
- three-Dimensional ultrasonography, Magnetic resonance imaging, myomectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Endocrine Disease, Infertility
Evaluation of Women With Endocrine and Reproductive-Related Conditions
This study was designed to allow inpatient and outpatient evaluation of women with a variety of reproductive and endocrine-related disorders for purposes of research and physician education.
- Conditions
- Endocrine Disease, Infertility, Leiomyoma, Endometriosis
- Trial name
- NCT00001850
- Where
- United States
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Secondary Dysmenorrhea, Dysmenorrhea
Iyengar Yoga Therapy for Dysmenorrhea and Endometriosis
The purpose of this clinical trial is to look at the effectiveness of prescribing yoga classes to patients with dysmenorrhea (irregular or painful periods), or other menstrual disorders on patients' self reported pain and quality…
- Conditions
- Secondary Dysmenorrhea, Dysmenorrhea, Dysmenorrhea Secondary, Polycystic Ovary Syndrome
- Trial name
- NCT03784976
- Testing
- Iyengar Yoga Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Illinois at Urbana-Champaign
Uterine Fibroid, Uterine Sarcoma
Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids
Myomectomy was preferably applied in females with reproductive requirements, which could be achieved by transumbilical laparoendoscopic single-site surgery (TU-LESS) or multi-port laparoscopic surgery (MPLS).
- Conditions
- Uterine Fibroid, Uterine Sarcoma, Uterine Leiomyosarcoma
- Trial name
- NCT06244251
- Testing
- TU-LESS, MPLS
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- West China Second University Hospital
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Leiomyoma
Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization
Uterine fibroid embolization (UFE) is now an accepted treatment of uterine fibroids. However the procedure is often very painful and, in many centres, patients are admitted overnight with patient controlled analgesic (PCA) pumps…
- Trial name
- NCT02270255
- Testing
- Superior hypogastric nerve block, 0.75% Ropivacaine, Subcutaneous injection
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Uterine Fibroid
Evaluating Efficacy of Intravenous Carbetocin Versus Intramyometrial Injection of Adrenaline in Reducing Blood Loss
Uterine fibroids, affecting 20-50% of all women ,and are benign tumors that arise from myometrial cells of the uterine smooth muscle tissue.
- Trial name
- NCT05986266
- Testing
- Carbetocin
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Egymedicalpedia
Uterine Fibroid, Myoma;Uterus
INTERVENTION WITH TRANEXAMIC ACID TO REDUCE HAEMORRHAGE DURING LAPAROSCOPIC MYOMECTOMY
This research is planned as a randomised double-blind controlled trial. interventions to reduce haemorrhage during laparoscopic myomectomy for fiboids is important.
- Conditions
- Uterine Fibroid, Myoma;Uterus, Tranexamic Acid Adverse Reaction
- Trial name
- NCT04192643
- Testing
- Tranexamic Acid 100 MG/ML
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alkü Alanya Education and Research Hospital
Uterine Fibroid
Design of an Intra-operative Blood Conservation Pathway at Open Myomectomy
Uterine fibroids are benign uterine masses that can be removed through a surgical procedure called a myomectomy. Myomectomy is often associated with a significant amount of blood loss for the patient.
- Trial name
- NCT03211481
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Renal Tumor Histology, Kidney Cancer
Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes
This study will investigate the frequency, clinical phenotype, management and molecular genetic defects of heritable kidney cancer syndromes. Families with kidney cancer with known or suspected genetic basis will be enrolled.
- Conditions
- Renal Tumor Histology, Kidney Cancer, Renal Cell Carcinoma, Familial Renal Cancer
- Trial name
- NCT05534854
- Testing
- Gene test
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Uterine Myoma, Surgery, Laparoscopic
Safety and Efficacy of Using a Novel Full Visual Access Platform System in Transvaginal Hysterectomy
The modified vNOTES hysterectomy was accomplished and validated for efficacy and safety using a multi-access vaginal confinement instrument with a fully visualised vaginal access platform.
- Trial name
- NCT06658145
- Testing
- Vnotes surgery using fully visualised surgical instruments, Vnotes surgery using traditional surgical instruments
- Where
- China
- Volunteers
- 94 people
- Sponsor
- China-Japan Friendship Hospital