Clinical trials: Focus of Study
Adrenocortical Carcinoma, Localized Resectable Neuroblastoma
Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
This natural history study is collecting health information about infants with adrenal masses found on prenatal and/or neonatal imaging.
- Conditions
- Adrenocortical Carcinoma, Localized Resectable Neuroblastoma, Precancerous Condition
- Trial name
- NCT00445718
- Testing
- computed tomography, 3-Tesla magnetic resonance imaging, Abdominal Sonogram
- Where
- 45 sites in United States, Australia and 1 more
- Volunteers
- 97 people
- Sponsor
- Children's Oncology Group
Hope, Nursing
The Effect of the Solution-Focused Approach on Social Participation Skills and Hope in Children Living in Residential Care Objective: This Study Aimed to Evaluate the Effect of a Solution-focused Approach Program on the Hope Levels and Social Participation Skills of Children Living in Institutional
his study examined whether a solution-focused approach program could improve hope and social participation skills in children living in institutional care.
- Conditions
- Hope, Nursing, Social Acceptance
- Trial name
- NCT07135908
- Testing
- solution-oriented approach
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
The Study Will Focus on no Specific Conditions
Abstract' Content and GPs' Confidence in the Conclusion
Objective: The aim of this study is to assess the impact of reporting, in abstracts of randomized controlled trials, 1) the funding sources and 2) the conflicts of interest (COIs) of the authors on General Practitioners'…
- Trial name
- ACOPI (NCT01679873)
- Testing
- Assess one type of abstract in the randomized arm
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Hotel Dieu Hospital
Partial Epilepsy
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
Primary objective: To evaluate the safety and tolerability of cenobamate in pediatric subjects 2-17 years of age with partial-onset (focal) seizures
- Trial name
- NCT05067634
- Testing
- Xcopri
- Where
- 35 sites in United States, Australia and 5 more
- Volunteers
- 154 people
- Sponsor
- SK Life Science, Inc.
Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Study of Tumor Samples From Patients With Ewing Sarcoma
This laboratory study is looking at tumor samples from patients with Ewing sarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and…
- Trial name
- NCT00898053
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Oncology Group
Neuroblastoma
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00017368
- Testing
- filgrastim, sargramostim, carboplatin
- Where
- 9 sites in United States, Australia
- Volunteers
- 42 people
- Sponsor
- Children's Oncology Group
The Focus of Study is to Elucidate Which Are the Factors Requiring the Duodenostomy and Which Postoperative Course is for These Patients
Duodenostomy to Treat Duodenal Perforation
In this study the investigators focused on duodenal perforations, requiring a tube duodenostomy and have analyzed the main features, that have influenced the surgical choices. Five patients were enrolled.
- Trial name
- NCT05359029
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Foggia
Brain Tumor, Central Nervous System Tumor
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
RATIONALE: Sodium thiosulfate may reduce or prevent hearing loss in young patients receiving cisplatin for cancer. It is not yet known whether sodium thiosulfate is more effective than no additional treatment in preventing…
- Conditions
- Brain Tumor, Central Nervous System Tumor, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
- Trial name
- NCT00716976
- Testing
- sodium thiosulfate, examination
- Where
- 76 sites in United States, Australia and 1 more
- Volunteers
- 131 people
- Sponsor
- Children's Oncology Group
Anemia
Appropriate Complmentary Feeding Strategies in Infants
The purpose of this study has been to understand the prevalence of under nutrition and develop effective interventions for improving growth and micronutrient status of infants receiving complementary foods.
- Trial name
- CFS (NCT01412411)
- Testing
- Nutritionl Education, Oral Iron Supplementation along with Nturition Eductaion, Multiple micronutrient fortification plus Nutrition Education
- Where
- Pakistan
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma
This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with…
- Conditions
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Trial name
- NCT01825902
- Testing
- fluorine F 18 fluorothymidine, fludeoxyglucose F 18, positron emission tomography
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion
A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease
This is a parallel, Phase 2a, double-blind, 6-arm study for the treatment of primary focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD).
- Trial name
- RESULT (NCT06500702)
- Testing
- frexalimab, brivekimig, rilzabrutinib
- Where
- 79 sites in United States, Argentina and 20 more
- Volunteers
- 84 people
- Sponsor
- Sanofi
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
Localized Scleroderma
Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized Scleroderma
The study aims at evaluating the efficacy of the fractional carbon dioxide laser as a new modality for treatment of localized scleroderma and to compare its results with the well established method of UVA 1 phototherapy.
- Trial name
- NCT02002897
- Testing
- Fractional carbon dioxide laser, Ultraviolet A1 phototherapy (UVA1)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Focal Segmental Glomerulosclerosis, Minimal Change Disease
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and tablets, and assess changes in proteinuria after once-daily dosing over 108 weeks.
- Conditions
- Focal Segmental Glomerulosclerosis, Minimal Change Disease, Immunoglobulin A Nephropathy, IgA Vasculitis
- Trial name
- EPPIK (NCT05003986)
- Testing
- Sparsentan
- Where
- 47 sites in United States, Germany and 6 more
- Volunteers
- 67 people
- Sponsor
- Travere Therapeutics, Inc.
Focus of Study: Cognitive Surgical Skill Acquisition
Educational Study of Multimedia in Surgical Skills Training in Colorectal Surgery
To practice independently surgeons require competency in surgical skills, encompassing a combination of technical and non-technical skills.
- Trial name
- NCT01866436
- Testing
- Multimedia group, Study Day Group
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Electroencephalography, Refractory Epilepsy
Clinical Utility of ESI in Presurgical Evaluation of Patients With Epilepsy
This study evaluates to what extend electrical source imaging (ESI) provides nonredundant information in the evaluation of epilepsy surgery candidates.
- Conditions
- Electroencephalography, Refractory Epilepsy, Brain Imaging, Surgery
- Trial name
- CUESIPE (NCT03533530)
- Testing
- Low-density ESI (LD ESI), High-density ESI (HD ESI), No electrical source imaging (ESI)
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Epilepsy, Complex Partial Seizures
An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures.
The purpose of this open-label extension study is to demonstrate that RWJ-333369 is safe as long-term add-on treatment of partial onset seizures.
- Conditions
- Epilepsy, Complex Partial Seizures, Epilepsy, Complex Partial, Epilepsies, Partial
- Trial name
- NCT00991757
- Testing
- carisbamate
- Volunteers
- 991 people
- Sponsor
- SK Life Science, Inc.
Epilepsies, Epilepsies, Focal
Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies
With this study the Investigator expects to develop a precise patient-centered model of care by means of home ultra-long-term EEG monitoring with a minimally invasive wearable EEG device (sqEEG).
- Conditions
- Epilepsies, Epilepsies, Focal, Epileptic Encephalopathy
- Trial name
- EMIRE (NCT06855901)
- Testing
- Ultra-longterm EEG monitoring at home by means of a scubscalp electrode implant.
- Where
- 4 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Drug-resistant Focal Epilepsies in Pediatric Population
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
Brain somatic mutations are increasingly recognized as a major cause of focal epilepsies. These include mTOR pathway mutations underlying cortical malformations such as focal cortical dysplasia and hemimegalencephaly, and SLC35A2…
- Trial name
- GENEPHY (NCT02890641)
- Testing
- Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Benign Prostate Hypertrophy(BPH)
Transurethral Focal Laser Ablation Versus Transurethral Prostatectomy For Management Of Benign Prostatic Obstruction
Introduction and objectives: Laser prostatectomy has become an increasingly popular and effective alternative to transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH).-.
- Trial name
- NCT07196475
- Testing
- FOCAL LASER ABLATION OF PROSTATE
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ain Shams University