Clinical trials: Functional Constipation
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Functional Constipation in Children
Preliminary Results of Laparoscopic Assisted Transanal Proximal Rectosigmoidectomy Combined With Malone Antegrade Continence Enema for the Management of Intractable Functional Constipation in Children
Technique for surgical management of intractable functional constipation
- Trial name
- NCT07180680
- Testing
- laparoscopic assisted transanal proximal rectosigmoidectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Functional Gastrointestinal Disorders, Infant Conditions
Prevalence of FGIDs and Probiotics Study
This is a study to evaluate the prevalence of FGIDs in infants using the Thai version of Rome IV diagnostic questionnaire for functional gastrointestinal disorders in infants and evaluate the efficacy of Limosilactobacillus…
- Trial name
- PROOF (NCT06309199)
- Testing
- Biogaia
- Where
- Thailand
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Constipation - Functional
Acupuncture Versus Biofeedback Training on Bowel Motility in Children With Functional Constipation
: Functional constipation is the most common gastrointestinal disorder affecting about 14 % of the global population and it negatively impacts the quality of life of those affected (Suares and Ford,2011).
- Trial name
- NCT06618326
- Testing
- Acupuncture, biofeedback
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Constipation - Functional
Evaluation of the Effectiveness of a Mobile Application in the Treatment of Children With Functional Constipation
This randomized, double-blind clinical trial evaluates the effectiveness of use of a mobile health application in supporting the treatment of functional constipation in children aged 4 to 18 years.
- Trial name
- NCT07025135
- Testing
- comparison between use of mobile app, Patient-caregiver dyad using printed recommendations
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk
Constipation, Constipation Chronic Idiopathic
A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding chronic constipation
- Conditions
- Constipation, Constipation Chronic Idiopathic, Constipation - Functional, Constipation (Excl Faecal Impaction)
- Trial name
- NCT04148248
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Constipation - Functional, Constipation
A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation
The goal of this pilot feasibility randomized controlled trial is to determine whether Actazin (kiwifruit extract) is a feasible and effective alternative to polyethylene glycol 3350 (PEG 3350) for maintenance therapy in children…
- Conditions
- Constipation - Functional, Constipation, Constipation Aggravated
- Trial name
- NCT06836024
- Testing
- Actazin chewable tablet, PEG 3350, Chewable Tablet
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Infantile Colic, Constipation - Functional
Bowel And Bladder Function in Infant Toilet Training
The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age.
- Conditions
- Infantile Colic, Constipation - Functional, Bladder Dysfunction, Toilet Training
- Trial name
- BABITT (NCT04082689)
- Testing
- Assisted Infant Toilet Training
- Where
- 6 sites in Sweden
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Functional Constipation (FC)
Acupuncture for Children with Functional Constipation
Background of the study: Functional constipation (FC) is common in children and poses a significant burden to patients, their families and the healthcare system.
- Trial name
- ACU-PILOT (NCT06836362)
- Testing
- Acupuncture treatment
- Volunteers
- 18 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Functional Gastrointestinal Disorders
Evolution of Functional Gastrointestinal Disorders in Infants Fed With a New Infant Formula
This study aims to assess the evolution of functional gastrointestinal disorders (FGIDs) in infants fed with a new infant formula, using the Gastrointestinal (GI) and gastroesophageal reflux (GER) (GIGER) scale through an…
- Trial name
- NCT06488274
- Testing
- New infant formula
- Where
- 4 sites in France
- Volunteers
- 139 people
- Sponsor
- United Pharmaceuticals
Functional Constipation, Therapeutic Touch
Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children
The aim of the study is to determine the effect of therapeutic touch on functional constipation in infants and young children.
- Conditions
- Functional Constipation, Therapeutic Touch, Infants, Children
- Trial name
- NCT06353841
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Constipation - Functional, Pediatric
Comparison of Two Interventions in Children with Functional Constipation
The purpose of this study; to compare the effects of therapeutic motor control interventions and conventional treatment in children with functional constipation on symptoms, spinal posture and mobility and trunk muscles endurance.
- Trial name
- NCT05371678
- Testing
- Therapeutic motor control interventions, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Abant Izzet Baysal University
Functional Constipation, Irritable Bowel Syndrome With Constipation
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria…
- Trial name
- NCT04026113
- Testing
- Linaclotide
- Where
- 115 sites in United States, Belgium and 12 more
- Volunteers
- 438 people
- Sponsor
- AbbVie
Functional Constipation, Fecal Incontinence in Children
Effect of MiniGo As Add-on to Oral Laxatives for Children with Constipation and Fecal Incontinence
The goal of this clinical trial is to compare combination therapy with low volume trans anal irrigation (TAI) and oral laxatives to monotherapy with oral laxatives in children with functional constipation and fecal incontinence.
- Trial name
- NCT05570318
- Testing
- Polyethylene Glycols, Low volume trans anal irrigation
- Where
- 3 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Functional Constipation in Children
Is Vitamin D Deficiency Linked to Functional Constipation In Children
Constipation is one of the most common causes of patient visits to pediatric clinics. Prevalence of constipation is estimated between 1.9-27.2% in the USA (Rasquin et al., 2006).
- Trial name
- NCT06657313
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Gastrointestinal Disorder, Functional, Regurgitation, Gastric
Transition to Infant Formula Feeding on Gastrointestinal Regurgitation (TIGER) Study
To compare the frequency of regurgitation and other digestive outcomes between infants who receive an infant formula based on whole goat milk and an infant formula based on cow milk proteins during the transition period from…
- Conditions
- Gastrointestinal Disorder, Functional, Regurgitation, Gastric, Colic, Infantile, Constipation - Functional
- Trial name
- TIGER (NCT05363553)
- Testing
- Infant formula based on whole goat milk, infant formula based on cow milk proteins
- Where
- Thailand
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Dairy Goat Co-operative (N.Z.) Limited
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Constipation - Functional
Effect and Safety of the Dietary Supplement Mannite in Pediatric Patients With Chronic Functional Constipation
Functional constipation is a widely prevalent pediatric issue, with a prevalence in some studies as high as 32.2%. Treatment consists of a combination of behavioral and pharmacological interventions (mainly, administration of…
- Trial name
- MANNAPED (NCT06404853)
- Testing
- Manna
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Functional Constipation, Fecal Impaction
Comparison of Efficacy & Tolerability Of PEG 4000 Versus PEG 3350+ Electrolytes for Pediatric Fecal Disimpaction
Childhood constipation is a common but serious gastrointestinal disorder prevalent worldwide. In 90-95% of children, it is of functional origin.
- Conditions
- Functional Constipation, Fecal Impaction, Constipation - Functional, Constipation Chronic Idiopathic
- Trial name
- NCT06349031
- Testing
- Administration of Polyethylene Glycol (PEG) 4000 as per treatment allocation to participants, Administration of Polyethylene Glycol (PEG) 3350 + Electrolyte as per treatment allocation to participants
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Medical Sciences and SUM Hospital