Clinical trials: Functional Disability
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Neurofibromatosis Type 1
Functional Imaging and Reading Deficit in Children With NF1
A monocenter pilot study on the acceptability and feasibility of a functional MRI protocol in children with NF1 with or without reading disabilities.
- Trial name
- NCT02422732
- Testing
- Neuropsychological assessments, morphological and functional MRI (fMRI), genetic analysis
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Toulouse
Learning Disabilities, Cerebral Palsy
Efficacy of AAC for Functional Communication
There is a considerable number children who are unable to speak, and our currently not being provided with any AAC options in their therapeutic facilities.
- Conditions
- Learning Disabilities, Cerebral Palsy, Down Syndrome
- Trial name
- NCT04583332
- Testing
- Rhymes, Individual Items in Rhymes, Objects
- Where
- Pakistan
- Volunteers
- 12 people
- Sponsor
- Riphah International University
Down Syndrome, Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Many individuals with Down syndrome (DS) have breathing problems during sleep. This is called obstructive sleep apnea syndrome (OSAS).
- Trial name
- TRIO (NCT01808508)
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Children's Hospital of Philadelphia
Developmental Delay
Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
Background: People show changes in brain activity when they watch other people do actions. This may be part of early social and communication skills.
- Trial name
- NCT03307317
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Motor Coordination or Function; Developmental Disorder
Project for Cognitive Advancement in Infants With Neuromotor Disorders
The purpose of this longitudinal study is to examine the ongoing interaction between the domains of cognitive and motor development in infants with neuromotor disability, and to compare outcomes of two groups of infants receiving…
- Trial name
- CAN-Do (NCT02673658)
- Testing
- Motor + problem solving, body weight support training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duquesne University
Fragile X Syndrome
Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome
To explore the efficacy, safety and tolerability of STX209 (arbaclofen) administered for the treatment of social withdrawal in adolescents and adults with fragile X syndrome (FXS)
- Trial name
- Harbor-A (NCT01282268)
- Testing
- arbaclofen
- Where
- 24 sites in United States
- Volunteers
- 125 people
- Sponsor
- Seaside Therapeutics, Inc.
Down Syndrome
Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome
The aim of the study is to evaluate the clinical efficacy of a known diuretic drug, Bumetanide, in terms of improvement of memory and psychological functioning in children and adolescents with Down syndrome (DS), in order to…
- Trial name
- NCT06465823
- Testing
- Bumetanide
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Stefano Vicari
Neuromuscular Diseases, Physical Disability
Physical Status and Upper Airway Function in Neuromuscular Patients
Inside of studies that report an upper airway function impaired, the upper limb strength has been demonstrated to be determinant in breath, speech and swallow performance.
- Conditions
- Neuromuscular Diseases, Physical Disability, Airway Disease
- Trial name
- NCT04473612
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cornelia de Lange Syndrome
Evaluation of Autonomic Function in Individuals With Cornelia de Lange Syndrome (CdLS)
Based on survey data, individuals with Cornelia de Lange Syndrome (CdLS) often experience symptoms of autonomic dysfunction however there are no reported studies in which these patients have had objective testing of the autonomic…
- Trial name
- NCT03113877
- Testing
- Autonomic Dysfunction Testing
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Cerebral Palsy (CP), Hand Functions
Hand-10 Questionnaire in Children With Unilateral Cerebral Palsy
A Turkish version of the Hand-10 (unabbreviated) questionnaire has been developed, but its validity and reliability in cerebral palsy has not yet been proven.
- Trial name
- NCT06887530
- Testing
- Hand-10 questionnaire and ABILHAND-kids questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gazi University
Mental Retardation
Effects of Different Dual-Task Exercises in Children With Mild Mental Retardation
The purpose of this study is to investigate the effects of motor-motor and motor-cognitive dual-task exercises applied to children with mild mental retardation on their functional mobility, balance, cognitive function, and…
- Trial name
- NCT07028333
- Testing
- Motor-Motor Dual Task Exercise Group, Motor-Cognitive Dual Task Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Istanbul University - Cerrahpasa
Intellectual Impairment
Effects of Balance Training on Gait and Functional Strength in Children With Intellectual Disabilities
Intellectual impairment is a developmental condition that first appears in childhood and causes substantial intellectual or cognitive limitations as well as inadequate adaptation to the demands of daily life.
- Trial name
- NCT05922215
- Testing
- Dynamic Balance training, Static balance training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Sickle Cell Disease, Pain
Preliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCD
Pain is the primary complication of sickle cell disease (SCD), including vaso-occlusive crises and more persistent, chronic pain.
- Trial name
- NCT04388241
- Testing
- The Balance Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's National Research Institute
Down Syndrome, Balance Impairment
Vestibular Stimulation Versus Foot Intrinsic Muscle Exercises in Children With Down Syndrome
This study will compare the effects of vestibular stimulation exercises and foot intrinsic muscle exercises on balance and functional mobility in children with Down syndrome aged 4-15 years.
- Conditions
- Down Syndrome, Balance Impairment, Functional Mobility
- Trial name
- VESTIB-FIME (NCT07778654)
- Testing
- Vestibular Stimulation Exercises, Foot Intrinsic Muscle Exercises
- Volunteers
- 48 people
- Sponsor
- Shalamar Institute of Health Sciences
Down Syndrome (DS), Balance Assessment
Effects of a Structured Physical Activity Program on Balance and Functional Performance in Children With Down Syndrome
Children with Down syndrome commonly exhibit hypotonia, impaired balance, and reduced functional mobility. This study aimed to evaluate the effects of a structured yoga-based physical activity program on balance and functional…
- Conditions
- Down Syndrome (DS), Balance Assessment, Physical Activities, Yoga
- Trial name
- DS-YOGA (NCT07534085)
- Testing
- Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ankara University
Anemia Acute, Fatigue
ABC - A Post Intensive Care Anaemia Management Trial
On discharge from intensive care (ICU) patients are often severely anaemic (have a low level of haemoglobin (Hb) in their red blood cells (RBC)). Anaemia can persist for many months making patients feel tired and fatigued.
- Conditions
- Anemia Acute, Fatigue, Physical Disability, Quality of Life
- Trial name
- NCT04591574
- Testing
- Red Blood Cells (Transfusion)
- Where
- United Kingdom
- Volunteers
- 346 people
- Sponsor
- University of Edinburgh
Intellectual Disability, Mild
Biofeedback Training's Impact on Cognitive and Motor Skills in Kids With Intellectual Disabilities
The expected outcome of the study is to confirm or reject the hypothesis that traditional rehabilitation in combined with biofeedback training produces better results in improving motor and cognitive functions, relative to…
- Trial name
- NCT06120686
- Testing
- Biofeedback method, Conventional therapy program
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Aleksandra Kiper
Healthy Volunteers
Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities
This study will evaluate new assessment tools and equipment and new ways of using existing tools and equipment in the NIH Clinical Center s Rehabilitation Medicine Department in order to maximize patients function.
- Trial name
- NCT00747955
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)