Clinical trials: Functional Disorder
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a MNP
The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient…
- Trial name
- ZEED2 (NCT02758444)
- Testing
- Micronutrient Powder (MNP) + 15 mg Zn, MNP + 10 mg Zn, MNP + 5 mg Zn
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hemophagocytic Lymphohistiocytosis, X-Linked Lymphoproliferative Disorders
Stem Cell Transplant for Immunologic or Histiocytic Disorders
This study tests the clinical outcomes of a preparative regimen of fludarabine (FLU), anti-thymocyte globulin (ATG)/or Campath, and melphalan; followed by hematopoietic stem cell transplant, and a post transplant regimen of…
- Conditions
- Hemophagocytic Lymphohistiocytosis, X-Linked Lymphoproliferative Disorders, Chediak-Higashi Syndrome, Griscelli Syndrome
- Trial name
- NCT00176865
- Testing
- Stem Cell Transplant, Fludarabine, Melphalan
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Multiple Sclerosis
Body Awareness, Trunk Stability, and Arm Function in MS
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
- Trial name
- NCT07151534
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Complex Regional Pain Syndrome I of Upper Limb, Pain
THE EFFECTS OF FUNCTIONAL ELECTRICAL STIMULATION-ASSISTED BICYCLE ERGOMETRY IN PATIENTS DIAGNOSED WITH COMPLEX REGIONAL PAIN SYNDROME.(CRPS)
The goal of this clinical study is to evaluate the effectiveness of functional electrical stimulation (FES)-assisted cycling in patients with post-stroke Complex Regional Pain Syndrome (CRPS) Type 1.
- Trial name
- CRPS (NCT07570199)
- Testing
- Functional Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zeynep Nur Köseoğlu
Anterior Cruciate Ligament Injury, Quadriceps Dysfunction
Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
FROM RISK FACTORS TO THE PREVENTION OF LONG-TERM CONSEQUENCES AFTER CRUCIATE LIGAMENT INJURY (ACL injury) - This is a research project where we seek new knowledge about why some people have a high risk and others a low risk of…
- Conditions
- Anterior Cruciate Ligament Injury, Quadriceps Dysfunction, Knee Joint Loading, Anterior Cruciate Ligament Reconstruction
- Trial name
- ExeLoadBioPTOA (NCT06892899)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- May Arna Risberg
Behavioral and Emotional Disorder With Onset in Childhood
Emotional Dysregulation and Other Psychopathological Dimensions in Clinical Preschoolers
The purpose of the study is to investigate the emotional-behavioral dysregulation and its possible correlation with the main demographic and psychopathological variables in a sample of preschool children with internalizing and…
- Trial name
- NCT07805668
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Fondazione Stella Maris
Ophthalmological Disorder
Effect of Binocular Treatment Using a Dichoptic Reading Application in Children With Convergence Insufficiency.
Convergence insufficiency is a common disorder of binocular vision that can appear as early as childhood after visual effort, and is often associated with a variety of symptoms such as eyestrain, headaches, blurred vision and…
- Trial name
- ALEDICE (NCT06465615)
- Testing
- Self-education with dichoptic reading on tablet, Conventional orthoptic rehabilitation
- Volunteers
- 26 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Type 1
Influence of Vitamin D on Vascular Function in Adolescents and Young Adults With Type 1 Diabetes
The purpose of this study is to study the role of low vitamin D levels on the health of blood vessels or vascular function in adolescents and young adults with type 1 diabetes.
- Trial name
- NCT01103817
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- The Hospital for Sick Children
Painful Osteoarthritis of the Knee
Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.
Pharmacological treatment of pain due to osteoarthritis of the knee often proves to be inadequate and/or cause intolerable side effects.
- Trial name
- NCT02688543
- Testing
- RF treatment, radiofrequency ablation, ultrasound
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital General de Jerez de la Frontera
Eustachian Tube Dysfunction
Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
The aim of this study is to determine which of the many Eustachian tube function tests (or combination of tests) is most helpful in finding out what is causing ear problems in children and adult patients with middle-ear diseases…
- Trial name
- NCT01974726
- Testing
- ET Stress test, Sonotubometry, Forced Response Test (FRT)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dwarfism, Turner's Syndrome
The Effects of Hormones in Growth Hormone-Treated Girls With Turner Syndrome
Turners Syndrome is a genetic condition in females that is a result of abnormal chromosomes. Patients with Turner syndrome are typically short, have abnormal physical features, and lack the physical changes normally associated…
- Trial name
- NCT00001343
- Testing
- Humatrope, Oxandrolone
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteogenesis Imperfecta (OI), Osteogenesis Imperfecta
Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta
This prospective observational investigation will examine the incidence and progression of cardiologic findings in individuals with OI across different age groups.
- Trial name
- OI Cardio (NCT07287241)
- Testing
- Imaging evaluation, Echocardiography
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli
Heart Defect, Congenital, Executive Dysfunction
Executive Function Intervention for Children With Complex Congenital Heart Disease
Children with complex congenital heart disease (cCHD) nowadays survive thanks to medical advances into their teenage years and adulthood. However, many of them have difficulties with so-called executive functions.
- Trial name
- E-Fit Heart (NCT07692958)
- Testing
- E-Fit Intervention
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Bea Latal
Aplastic Anaemia (AA), Allogeneic Haematopoietic Stem Cell Transplantation
Clinical Study on the Preservation of Ovarian Function in Patients With Aplastic Anemia Following Allogeneic Hematopoietic Stem Cell Transplantation Using Goserelin
This study is a prospective, randomized, controlled, multicenter clinical trial. It plans to enroll 132 female SAA patients aged 14-50 years from multiple medical centers nationwide who are scheduled to undergo allo-HSCT.
- Conditions
- Aplastic Anaemia (AA), Allogeneic Haematopoietic Stem Cell Transplantation, Ovarian Insufficiency
- Trial name
- NCT07552506
- Testing
- Goserelin Depot
- Where
- 5 sites in China
- Volunteers
- 132 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Thyroid Cancer
The Effect of the Number of Central Lymph Nodes on Changes in Parathyroid Function
This study collected data from patients who underwent thyroidectomy in the Breast and Thyroid Surgery Department of Shandong Provincial Hospital from January 2020 to December 2023 by reviewing medical records.
- Trial name
- NCT06432244
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shandong Provincial Hospital
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Demyelinating Diseases of the Central Nervous System, Child
Core Stability, Functional Capacity, Balance, Strength, and Fatigue in Pediatric Demyelinating Diseases
This study aims to evaluate balance ability, core stability, functional capacity, lower extremity muscle strength, and fatigue levels in children diagnosed with central nervous system demyelinating diseases, in order to…
- Conditions
- Demyelinating Diseases of the Central Nervous System, Child, Core Stability, Balance
- Trial name
- PEDI-CORE (NCT07654738)
- Testing
- No ADT
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Preterm, Parent-Child Relations
Sensory Optimization of the Hospital Environment
The long-term goal of this project is to improve the health and well-being of preterm infants and their parents. Although there is evidence to support positive multisensory interventions in the NICU, these interventions are often…
- Conditions
- Preterm, Parent-Child Relations, Parents, Development, Infant
- Trial name
- SOOTHE (NCT05230199)
- Testing
- SENSE multisensory program, Monitored standard of care
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- University of Southern California
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